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101.
Memory impairments and hippocampal modifications in adult rats with neonatal isolation stress experience 总被引:1,自引:0,他引:1
Kosten TA Karanian DA Yeh J Haile CN Kim JJ Kehoe P Bahr BA 《Neurobiology of learning and memory》2007,88(2):167-176
Early life events have profound consequences. Our research demonstrates that the early life stress of neonatal isolation (1-h individual isolation on postnatal days 2-9) in rats has immediate and enduring neural and behavioral effects. Recently, we showed neonatal isolation impaired hippocampal-dependent context conditioned fear in adult rats. We now expand upon this finding to test whether neonatal isolation impairs performance in inhibitory avoidance and in the non-aversive, hippocampal-dependent object recognition task. In addition to assessments of hippocampal-dependent memory, we examined if neonatal isolation results in cellular alterations in the adult hippocampus. This was measured with antibodies that selectively label calpain-mediated spectrin breakdown product (BDP), a marker of cytoskeletal modification that can have neuronal consequences. Neonatally isolated male and female rats showed impaired performance in both memory tasks as well as elevated BDP levels in hippocampal immunoblot samples. In tissue sections stained for BDP, the cytoskeletal fragmentation was localized to pyramidal neurons and their proximal dendrites. Interestingly, the hippocampal samples also exhibited reduced staining for the postsynaptic marker, GluR1. Neonatal isolation may render those neurons involved in memory encoding to be vulnerable to calpain deregulation and synaptic compromise as shown previously with brain injury. Together with our prior research showing enhanced striatal-dependent learning and neurochemical responsivity, these results indicate that the early experience of neonatal isolation causes enduring yet opposing region-specific neural and behavioral alterations. 相似文献
102.
Sarah M. Bannon Tenille C. Taggart Caitlin M. Kehoe K. Daniel O'Leary 《Personal Relationships》2020,27(2):385-400
The speed, or efficiency, in which people communicate is linked to positive interpersonal outcomes. However, no studies of communication efficiency have examined romantic partners, making it unclear whether efficient communication is linked to relationship satisfaction above and beyond previously identified communication skills (e.g., problem‐solving). We recruited dating couples (N = 56) to attend a laboratory session to complete survey measures and a collaborative communication task. Multilevel models demonstrated that both task efficiency (β = ?.36, p = .04) and self‐reported problem‐solving communication skills (β = .28, p = .002) were associated with relationship satisfaction. Results suggest that communication task efficiency can be meaningfully applied to the study of romantic relationships and couple communication skills. 相似文献
103.
Priscilla M. Schulz Patricia A. Resick L. Christian Huber Michael G. Griffin 《Cognitive and behavioral practice》2006,13(4):322-331
Opinions vary on the generalizability of empirically supported treatments to diverse populations in naturalistic settings and on the relative merits of delivering treatments through interpreters. The authors present statistical analyses of outcome data from a community mental health program that served foreign-born refugees resettled in the U.S. The program used a manualized, empirically supported treatment, Cognitive Processing Therapy, to address symptoms of PTSD in this population. Participants received psychological treatment in native languages either with a therapist who spoke their language or with a therapist who used an interpreter. Results demonstrated that treatment of PTSD was highly effective whether delivered directly or through an interpreter. 相似文献
104.
Martha C. Tompson Claudette B. Pierre Kathryn Dingman Boger James W. McKowen Priscilla T. Chan Rachel D. Freed 《Journal of abnormal child psychology》2010,38(1):105-117
Across development, maternal depression has been found to be a risk factor for youth psychopathology generally and youth depression
specifically. Maternal Expressed Emotion (EE) has been examined as a predictor of outcome among youth with depression. The
present study explored the associations between youth psychopathology and two predictors–maternal depression within the child’s
lifetime and maternal EE–in a study of children at risk for depression. One hundred and seventy-one youth, ages 8–12, and
their mothers participated. To assess maternal and youth psychopathology, dyads were administered structured diagnostic assessments,
and mothers and children completed self-report measures of their own depressive symptoms. In addition, mothers completed the
Achenbach Child Behavior Checklist–Parent Report Version (CBCL) for their children. Maternal EE was assessed based on the
Five Minute Speech Sample. History of maternal depression was associated with high maternal EE, and the combination of maternal
depression history and maternal EE was associated with children’s own reports of higher depressive symptoms. Current maternal
depressive symptoms were associated with mothers’ reports of children’s Internalizing scores on the CBCL, and maternal depression
history, current maternal depressive symptoms, and maternal EE were strongly associated with mothers’ reports of children’s
Externalizing and Total Problem scores on the CBCL. History of maternal depression and a rating of high or borderline Critical
EE (characterized by maternal critical comments and/or reports of a negative relationship) were independently associated with
children’s depression diagnoses. 相似文献
105.
Using interstimulus intervals (ISIs) of 125, 250, and 500 msec in trace conditioning of the rabbit nictitating membrane response, the offset times and durations of conditioned responses (CRs) were collected along with onset and peak latencies. All measures were proportional to the ISI, but only onset and peak latencies conformed to the criterion for scalar timing. Regarding the CR's possible protective overlap of the unconditioned stimulus (US), CR duration increased with ISI, while the peak's alignment with the US declined. Implications for models of timing and CR adaptiveness are discussed. 相似文献
106.
Previous research by Morris and Blanton (1994b) used the Denominational Support Service Checklist (DSSC) to determine whether or not denominations were providing support services in any organized/systematic way to the clergy and their wives in their denomination. The DSSC has a yes/no format containing 21 support services that are divided into four areas of support. The four areas of support services included psychological services (3), career development services (6), family oriented services (7), and financial services (5). As a follow-up to the previous study, the purpose of this study was to examine the perceptions of clergy husbands and their wives regarding the availability and importance of support services provided by their sponsoring denomination. The sample of the study included 136 ordained married clergy males and their non-clergy spouses (n=272) randomly selected from six denominations in the United States. The six denominations included the Southern Baptist Convention (SBC); Lutheran Missouri Synod (LMS); Church of God, Cleveland, Tennessee (COG); Seventhday Adventists (SDA); the American Baptist Church (ABC); and the Episcopal Church (EC). Each husband and wife completed The Perceived Availability of Denominational Support Services (PADSS) and The Perceived Importance of the Denominational Support Service (PIDSS). The PADSS has a yes/no format and the PIDSS is a 3 point Likert-type questionnaire that corresponds identically (e.g., 21 items divided into four support areas) with the DSSC. Findings from the study indicated that a majority of clergy and their wives perceived that their sponsoring denominations were not making available those services that they perceived were important. Additionally, gender differences in reports of availability and importance were found indicating that some denominations may not be providing support services that enhance the quality tof life for the entire clergy family system. Recommendations and suggestions are made to encourage and guide denominations in providing support services for clergy families. 相似文献
107.
Michelle Kehoe Helen Bourke-Taylor David Broderick 《Social Psychology of Education》2018,21(1):189-207
Students attending schools today not only learn about formal academic subjects, they also learn social and emotional skills. Whole-school restorative practices (RP) is an approach which can be used to address student misbehaviour when it occurs, and as a holistic method to increase social and emotional learning in students. The aim of this study was to explore the impact of RP on student behaviour from the perspectives of students and teachers. Six schools participated in interviews and focus groups. Students and teachers were asked about the use of RP and the impact on behaviour. Students and teachers identified five main themes: greater harmony, increased empathy towards others, awareness of one’s own behaviour and being accountable for that, increased respect, and reflective thinking. These aspects increase students’ social skills. This paper discusses a new framework which describes the positive impact of RP on student behaviour and thinking. The findings have broad implications for school communities and highlight the need to move towards more relational behaviour management approaches. 相似文献
108.
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110.
Priscilla Roth 《The International journal of psycho-analysis》2001,82(3):533-543
The author argues that there are distinctly different kinds of transference interpretation, each of which might be valid in particular circumstances in analysis, but which contain and imply different understandings of what is meant by a ‘transference interpretation’. She suggests that transference interpretations may be at any one of four different levels, and she describes these levels as ranging from interpretations that point to links between current events in the analysis and events from the patient's history, through interpretations that link events in the patient's external life to the patient's often unconscious phantasies about the analyst and the analysis, to interpretations that focus on the use of the analyst and the analytic situation to enact unconscious phantasy configurations, sometimes pulling the analyst into the enactment. Material from four consecutive sessions of an analysis is presented to illustrate how all levels of transference interpretation may be part of a lively and meaningful analysis, but how the level of interpretation may change as the level of understanding deepens within a session and from one session to the next. 相似文献