Neuroimaging studies in eating disorders

The understanding of the eating disorders (EDs) anorexia (AN) and bulimia nervosa (BN) has undergone remarkable advancements in the past decade. Most studies that have been done in AN show brain gray and white matter volume loss during the ill state that, at least in part, remit with recovery. Similar patterns occur for brain phospholipids assessed using magnet resonance spectroscopy (MRS). Imaging studies have been used to provide functional information regarding serotonin neuroreceptor dynamics, regional cerebral blood flow, or cerebral glucose metabolism. Such studies have implicated cingulate, frontal, temporal, and parietal regions in AN. Investigators have found that challenges such as food and body image distortions may activate some of these regions, raising the possibility that such studies may shed light on puzzling AN symptoms, such as body image distortions or extremes of appetitive behaviors. Emerging data suggest these disturbances persist after recovery from AN, suggesting the possibility that these are traits that may create a vulnerability to develop an ED. While fewer studies have been done in BN or binge eating disorder, there may be disturbances of serotonin metabolism in similar brain regions. Taken together, these findings give promise for future investigations with the hope of delineating brain pathways that contribute to the etiology of EDs     

Context specificity of conditioning and latent inhibition: Evidence for a dissociation of latent inhibition and associative interference

Conditioning may generalize from one context to another when latent inhibition (the effect on subsequent conditioning of prior unreinforced exposure to the stimulus) does not. Experiment 1 studied conditioned approach and licking by rats to a stimulus paired with the delivery of water and confirmed that latent inhibition could be abolished by a change of context, while prior aversive conditioning to the stimulus, produced by pairing it with mild shock, interfered with the acquisition of conditioned approach and licking regardless of this change of context. Thus even when conditioning and latent inhibition were measured in the same way, the former generalized across contexts, and the latter did not. Experiment 2 showed that the effects not only of unreinforced exposure to a stimulus but also of presentation of the stimulus uncorrelated with the delivery of water were confined to the context in which they occurred. Thus the generalization of conditioning from one context to another and the failure of latent inhibition to generalize cannot be attributed to the occurrence of rein-forcers during conditioning and their absence in latent inhibition. This conclusion was confirmed in Experiment 3, where animals received both aversive conditioning trials and unreinforced presentations of other stimuli in the treatment phase of the experiment, but were then conditioned to one of these stimuli paired with water. Once again, the effects of aversive conditioning transferred perfectly from one context to another, while those of unreinforced presentations did not. Latent inhibition, these results suggest, is not easily explained by supposing that animals associate an unreinforced stimulus with zero consequences and have to unlearn this association when the stimulus is then paired with a reinforcer.     

Hermeneutic analysis of virtuous exemplar narratives of Cambodian-American Buddhists and Christians

Virtuous exemplars embody the virtues of a cultural community, a dynamic, contextual understanding that is best explored by critical hermeneutic analysis. In order to describe their lives and refine the mental-health treatment of Cambodian immigrants, 12 virtuous exemplars from a Cambodian-American Buddhist and 12 from a Cambodian-American Christian population were interviewed. Grounded theory and a mixed-methods analysis were used. Rigor-enhancing strategies include triangulation, collaboration, member checking, and researcher reflexivity, as well as interviewing a comparison group of 12 Euro-American Christians. Cambodian-American Buddhists and Christians take their religion seriously, and it influences their daily lives. These Buddhists focus on perseverence in the present life and gaining merit for the next. The Christians focus on serving God and nurturing relationships in this life. They report that they are more different from the Cambodian-American Buddhists than Latent Semantic Analysis indicates, providing evidence of both religious and cultural distinctives among the subgroups.     

Generation to Generation: Passing on Religious and Spiritual Beliefs and Practices

Many families face difficulties in maintaining healthy relationships. Past research has identified that religious and/or spiritual beliefs and practices can enhance family well-being. Research has also shown that religious and/or beliefs and practices can shape the aging process. Yet there exists little information on the methods through which religious and/or spiritual beliefs are passed on to future generations. This study utilized Eriksonian conceptual ideas, and grounded theory methods to conduct interviews with 13 older adults on the process through which religious and/or spiritual beliefs are passed on to children and grandchildren. Ideas are discussed for practitioners based on study findings.     

Development of the Motivators of and Barriers to Health-Smart Behaviors Inventory

The Motivators of and Barriers to Health-Smart Behaviors Inventory (MB-HSBI) was developed for use in identifying self-reported motivators of and barriers to the following health-promoting behaviors (called health-smart behaviors) that should occur daily to help promote health and overcome illnesses/diseases: eating a healthy breakfast, eating healthy foods and snacks, drinking healthy drinks, and engaging in physical activity. The MB-HSBI was developed through several phases as part of a multisite study on modifying and preventing obesity. A central aspect of the larger study was to identify motivators of and barriers to the targeted health-smart behaviors among African American, Asian, Hispanic, and White adults. After establishing content validity and preliminary pilot testing, the MB-HSBI was administered to a national sample of 926 culturally diverse adults. Factor analyses and most of the internal consistency results supported multiple scales and subscales measuring motivators of and barriers to each of the targeted health-smart behavior domains. Scores correlated in expected directions with health self-efficacy and with importance of health-related behavioral goals. Pending further psychometric support of the MB-HSBI, this inventory or selected scales from it may serve as flexible and novel tools for (a) assessing motivators of and barriers to health-smart behaviors in community and clinical health promotion research studies and (b) developing assessment-based, culturally sensitive intervention programs that are customized to address the motivators of and barriers to health-smart behaviors identified in target communities, particularly those communities whose members are mostly racial/ethnic minorities and/or have low family incomes.     

The strength of the orienting response during blocking

In two experiments rats initially received appetitive Pavlovian conditioning with an auditory conditioned stimulus (CS). Subsequently this stimulus was presented in compound with a novel light and paired with the same appetitive reinforcer. In keeping with the outcome of many such experiments on blocking, there was very little evidence of appetitive conditioning during subsequent independent presentations of the light. Of main concern in the present experiments, however, was the influence of this training on the strength of the orienting response directed towards the light. When the light was first presented it elicited a strong orienting response. The strength of this response declined rapidly when the light was presented in compound with the previously trained auditory CS but more slowly when it was paired with the reinforcer either by itself or in conjunction with an initially neutral auditory stimulus. It is suggested that the extent to which the events following the light are accurately predicted determines the strength of orientation towards this stimulus.