The expression of c-Fos and colocalisation of c-Fos and glucocorticoid receptors in brain structures of low and high anxiety rats subjected to extinction trials and re-learning of a conditioned fear response

We designed an animal model to examine the mechanisms of differences in individual responses to aversive stimuli. We used the rat freezing response in the context fear test as a discriminating variable: low responders (LR) were defined as rats with a duration of freezing response one standard error or more below the mean value, and high responders (HR) were defined as rats with a duration of freezing response one standard error or more above the mean value. We sought to determine the colocalisation of c-Fos and glucocorticoid receptors-immunoreactivity (GR-ir) in HR and LR rats subjected to conditioned fear training, two extinction sessions and re-learning of a conditioned fear. We found that HR animals showed a marked decrease in conditioned fear in the course of two extinction sessions (16 days) in comparison with the control and LR groups. The LR group exhibited higher activity in the cortical M2 and prelimbic areas (c-Fos) and had an increased number of cells co-expressing c-Fos and GR-ir in the M2 and medial orbital cortex after re-learning a contextual fear. HR rats showed increased expression of c-Fos, GR-ir and c-Fos/GR-ir colocalised neurons in the basolateral amygdala and enhanced c-Fos and GR-ir in the dentate gyrus (DG) in comparison with LR animals. Our data indicate that recovery of a context-related behaviour upon re-learning of contextual fear is accompanied in HR animals by a selective increase in c-Fos expression and GRs-ir in the DG area of the hippocampus.     

On infinite EPR-like correlations

The paper investigates, in the framework of branching space–times, whether an infinite EPR-like correlation which does not involve finite EPR-like correlations is possible. The authors read earlier versions of this paper at the seminar ‘Chaos and Quantum Information’ at the Jagiellonian University in Kraków on April 16, 2007 and at the seminar ‘On Determinism’ at the University of Bonn on April 20, 2007.     

The Distance Function in Commutative ℓ-semigroups and the Equivalence in Łukasiewicz Logic

The equivalence connective in ukasiewicz logic has its algebraic counterpart which is the distance function d(x,y) =|x–y| of a positive cone of a commutative -group. We make some observations on logically motivated algebraic structures involving the distance function.     

Logic, Formal Methodology and Semantics in Works of Ryszard W��jcicki

For decades Ryszard Wójcicki has been a highly influential scholar in the community of logicians and philosophers. Our aim is to outline and comment on some essential issues on logic, methodology of science and semantics as seen from the perspective of distinguished contributions of Wójcicki to these areas of philosophical investigations.     

Positive effects of subclinical depression in prospective memory and ongoing tasks in young and old adults

Results reported in the literature show that depression can have either negative or neutral effects on prospective memory (PM). The goal of the present study was to broaden the analysis of depression-related effects on PM, with regard to the possibility that subclinical depression may have positive influence on PM. A total of 120 participants from four groups (young/old, subclinically depressed/non-depressed) completed event- and time-based PM tasks embedded in the linear orders task or stories task, respectively. In the event-based PM task no effects of depression were found, whereas depressed participants were more accurate in the time-based PM task, where higher monitoring during the last minute of the task was observed. It was also found that depressed participants built a mental model in the linear orders task more accurately than controls. Results of the present study are discussed with reference to the analytical rumination hypothesis.     

Influence of Religiosity on the Quality of Life and on Pain Intensity in Chronic Pancreatitis Patients After Neurolytic Celiac Plexus Block: Case-Controlled Study

The quality of life in patients with chronic pancreatitis (CP) is reduced due to their suffering of high levels of pain. It has been presented that quality of life can also be linked to religiosity and/or spirituality. The aim of this study is to assess the influence of religious practices on the quality of life and on the subjective level of pain in CP patients. Ninety-two patients (37 women and 55 men) with chronic pancreatitis were treated invasively for pain with neurolytic celiac plexus block (NCPB). The religiosity of the patients was recorded and served as a dichotomizer. Group 1 was for patients who claimed to have no contact with the church or to have very sporadic contact (N = 35 patients). Group 2 was for patients who claimed to have deep faith and were regular participants at church activities (N = 57 patients). Visual analogue scale was used to assess pain, while the quality of life was measured by using QLQ C-30 questionnaire adapted for chronic pancreatitis patients in Polish population. The patients were assessed prior to the pain-relieving intervention and subsequently 2 and 8 weeks after it. The intensity of pain was reduced in both groups significantly after performing the NCPB. Patients who declared a deep faith reported higher level of pain on the VAS scale prior to intervention than non-religious patients. Quality of life in both groups of patients significantly improved after NCPB. Following NCPB, global quality of life in patients who declared higher religiosity/church attendance was significantly higher (79.88) than for those patients who have no contact or sporadic contact with the church (44.21, P < 0.05). NCPB resulted in significant reduction of pain and increase in quality of life in both groups of patients with CP. Nevertheless, in the group declaring higher religiosity/church attendance, reported pain was higher, but, despite that, quality of life better. It may be concluded that religious practices might serve as an additional factor improving quality of life and coping in patients suffering from chronic pancreatitis.     

Gender Differences in Vivid Memories

Seventy-four adults (50% women) individually completed a memory questionnaire. They were given a definition of a flashbulb memory and were asked to describe their 3 most vivid memories. In addition, participants rated the described events for various characteristics (e.g., emotional load and personal importance) and provided their best estimate of the date of each event. Effects of gender on the content of vivid memories, their form, and their distribution were found. The influence of identity on the recollection of personal experiences and gender differences in the development of autobiographical memory are discussed.