恶性肿瘤的过度治疗及其防范

恶性肿瘤的过度治疗涉及到手术、放疗、化疗、靶向治疗、生物治疗等多个方面,严重影响了患者的生存质量。造成这一现象的原因是多方面的：患者由于对肿瘤的恐惧而形成过分关注;医生未及时更新治疗观念,过于注重对肿瘤的彻底杀伤,并对自己行医的过分保护;医院的不恰当管理。为了促进肿瘤治疗环境的合理化,我们应该防范过度治疗,加强宣传教育,完善医德医风,促进医疗改革的顺利完成。倡导合理、受益性治疗,使患者达到长期带瘤生存的目的。     

Are Christian/religious people poor tippers?

A web‐based survey was used to assess the relationships of religious faith and frequency of church attendance with tipping under conditions of good and bad service. Results indicated that Jews and those with no religion tipped more than Christians and members of other religions, but that the vast majority of Christians tipped at or above the normative 15% of bill size. Worship frequency also significantly interacted with service quality such that the tips of those who frequently worship vary with service quality less than the tips of those who worship less frequently. The practical implications of these results for service workers and restaurants or other service businesses with a large religious clientele are discussed.     

汶川地震三年半后中学生的感恩对创伤后成长的影响：社会支持的中介作用

采用感恩问卷、社会支持问卷和创伤后成长问卷对汶川地震三年半后的376名中学生进行调查,考察其感恩与社会支持对创伤后成长的影响,并检验社会支持在感恩与创伤后成长之间的中介作用。结果发现：（1）灾后中学生的创伤后成长水平较高,其中自我觉知的改变与人际体验的改变水平高于生命价值观的改变水平,女生人际体验的改变水平高于男生,初一学生的创伤后成长水平相对低于高年级学生;（2）感恩和社会支持可显著地正向预测创伤后成长;（3）社会支持在感恩与创伤后成长之间起着部分中介作用。这表明,汶川地震三年半后中学生的感恩可以直接正向预测创伤后成长,也可通过社会支持正向影响创伤后成长。     

Individual and Environmental Predictors of College Adjustment: Prevention and Intervention

In this study, an ecological model was used to expand the current understanding of what contributes to college adjustment. Individual and environmental variables, and their relative contributions to college adjustment, were explored. This study also included the additional feature of the examination of environmental variables as possible mediators between the individual variables and college adjustment. The sample included 240 college freshmen at a large urban university. As predicted, both groups of variables accounted for significant proportions of variance in college adjustment. Further, the combination of both groups explained a greater proportion of variance than did either group alone. Maladaptive coping and perceived university environment were the most essential to college adjustment. Surprisingly, social support and gender were not essential for college adjustment. However, the environmental variables proved to be significant partial mediators between the individual variables and college adjustment. Finally, possible interventions and suggestions for future research are outlined.     

慢性应激性抑郁发生中大鼠眶额叶多巴胺D1受体对谷氨酸及其NMDA受体的调节

本文旨在探讨慢性应激性抑郁发生过程中眶额叶多巴胺D1受体对谷氨酸(glutamic acid, Glu)及其N-甲基-D-天冬氨酸(N-methyl-D-aspartic acid, NMDA)受体的NR2B亚基的影响。实验通过建立慢性不可预见性温和应激(chronic unpredictable mild stress, CUMS)抑郁模型, 结合眶额叶微量注射多巴胺D1受体激动剂SKF38393和多巴胺D1受体拮抗剂SCH23390, 运用糖水偏爱测试、悬尾实验和敞箱实验等方法检测动物的行为表现, 采用高效液相色谱法(high-performance liquid chromatography, HPLC)和蛋白质免疫印迹法(Western blot, WB)来检测眶额叶内谷氨酸、多巴胺含量及NR2B和多巴胺D1受体的表达。结果显示, 与对照组相比, CUMS组大鼠表现出明显的抑郁样行为变化, 且眶额叶多巴胺含量降低, 其D1型受体表达降低, 谷氨酸含量升高, 其NMDA受体的NR2B亚基也明显上调; 注射SKF38393后可明显改善应激引起的抑郁样行为, 且眶额叶谷氨酸含量显著下降, NMDA受体的NR2B亚基表达也有所降低; 正常大鼠注射多巴胺D1受体拮抗剂SCH23390, 大鼠表现出和CUMS模型组相似的抑郁样行为, 且眶额叶谷氨酸含量升高, 其NMDA受体的NR2B亚基也明显上调。以上结果表明, 慢性不可预见性应激可能使眶额叶多巴胺释放减少, 从而使谷氨酸过量释放, NMDA受体过度激活, 导致抑郁发生。多巴胺抗抑郁作用是通过D1型受体抑制谷氨酸及其NMDA受体NR2B亚基表达来实现。     

Logit Model to Predict Outcomes of Litigated Employee Obesity Cases

Purpose  

Given that there are no specific legal protections for obese employees, the purpose of this study was to investigate the relationship between the litigated case characteristics and case outcomes when an employee is subjected to negative consequences in the workplace and subsequently sues the employer.     

网络成瘾症治疗方法研究进展

利用文献分析方法分析和总结了目前国内关于网络成瘾治疗方法的研究进展。简要回顾了网络成瘾症的概念、症状、诊断标准、分类和病因研究现状;介绍和分析了现有文献已报道的心理治疗、药物治疗、整合治疗单元、家庭治疗、社会支持治疗等方法;对网络成瘾治疗方法研究现状进行了讨论并提出了几点研究建议。     

医疗社会工作:现实意义和发展趋向

医疗社会工作是社会工作专业的重要实务领域之一,在西方发达国家的医疗事业中扮演着不可替代的角色,具有解决患者及其家属问题、处理医患关系,并促进公共卫生政策的改善等多种功能.从我国目前的发展来看,尚处于起步阶段,还有诸多需要努力的方面,包括完善相关政策、提高服务质量、修正教育模式、突出中国特色等.