Clinical perspectives on the combination of D-cycloserine and cognitive-behavioral therapy for the treatment of anxiety disorders

In a particular success for translational research agendas, characterization of the neuronal circuits underlying fear extinction, and basic research in animal extinction paradigms, has led to intervention studies examining the use of D-cycloserine (DCS) to enhance therapeutic learning from exposure-based cognitive-behavioral therapy (CBT). In this article, we review these intervention studies, and discuss DCS augmentation of CBT relative to more traditional combination-treatment strategies in the treatment of anxiety disorders. We offer an accounting, based on evidence for internal context effects, of current limitations in the combination of antidepressant or benzodiazepine medications with CBT and discuss the advantages of isolated-dosing strategies with DCS relative to these limitations. This strategy is contrasted with the chronic-dosing applications of DCS for schizophrenia and Alzheimer's disease, and future directions for isolated-dosing strategies are discussed.     

Classification of adults with problematic internet experiences: linking internet and conventional problems from a clinical perspective.

This article utilizes data from clinical reports of 929 adults to examine whether various problematic Internet experiences are distinctly different from or extensions of conventional problems. A TwoStep Cluster Analysis identified three mutually exclusive groups of adults, those with (1) online relationship problems and victimization; (2) online and offline problems; and (3) marital discord. Results suggest some initial support for the idea that problematic Internet experiences are often extensions of experiences and behaviors that pre-date the Internet. However, the Internet may be introducing some qualitatively new dimensions-such as an increased severity, an increased frequency, or unique dynamics-that require new responses or interventions.     

Primary or "specific" language impairment and children learning a second language

We review empirical findings from children with primary or "specific" language impairment (PLI) and children who learn a single language from birth (L1) and a second language (L2) beginning in childhood. The PLI profile is presented in terms of both language and nonlinguistic features. The discussion of L2 learners emphasizes variable patterns of growth and skill distribution in L1 and L2 which complicate the identification of PLI in linguistically diverse learners. We then introduce our research program, designed to map out common ground and potential fault lines between typically developing children learning one or two languages, as compared to children with PLI.     

The relationship between contrast sensitivity, gait, and reading speed in Parkinson's disease

Parkinson's disease (PD) results in reduced walking speed and visual difficulties, including difficulty reading (Davidsdottir, Cronin-Golomb, & Lee, 2005). PD is characterized by a reduction in dopamine, which is instrumental in determining a person's contrast sensitivity (CS). This study assessed the relationship between CS, gait (step length and walking speed), and reading speed in 18 non-demented PD volunteers with normal acuity. We found that CS correlated with walking speed (r = .57, p = .01), step length (r = .53, p = .02), and reading speed (r = .54, p = .02). Visual acuity (which has not been tied to dopamine in the same way) correlated with reading speed (r(s) = -.65, p = .004), but not with gait measures. We also assessed the contribution of age, education, and cognitive status (Shipley Institute of Living Scale) to these variables. We conclude that CS and age both play an important role in determining gait in PD, while reading speed is related to both acuity and CS, but not age.     

From Speechlessness to Presence

Spiritual direction, or the directed art of inner conversation, emerges from a psychological inflection in which we learn that radical inner otherness is the fuel of spirit. Spirit, manifesting between self and other incarnates through and in the subject, as well as through the other encountered as authentic subject. One individuates, then, by relating to the Self as a desiring subject. Moving in the direction of spirit, we push back dimension by dimension to get to one dimension. Eventually, we may encounter a numinous silence, an emptiness that is full.     

THE SOCIAL CONSTRUCTION OF EMOTIONS IN THE BHAGAVAD GĪTĀ

Religious texts and historical narratives are instrumental in defining appropriate emotions and moral reasoning in a culture. In the Bhagavad Gı tā, the warrior Arjuna is faced with a twofold dilemma: are his emotions appropriate and should emotions influence his actions? The Gı tā is thought to be a redacted text with three primary layers: the original verses, the Sāmkhya/Yoga layer, and the devotional bhakti layer. Cross‐cultural psychological theories of emotions are employed to analyze the layers of the Gı tā. It is argued that each of the three layers corresponds with one of three possible moral codes as proposed by R. A. Shweder and his colleagues (1997; 2000) : the Ethic of Autonomy (promoting personal well‐being and avoiding shame); the Ethic of Community (maintaining social order and emotional detachment); and the Ethic of Divinity (upholding cosmic order and endorsing emotional devotion). These three perspectives remain relevant for deciding emotionally laden moral dilemmas today.