Temporal processing capabilities in repetition conduction aphasia

This study investigates the temporal resolution capacities of the central-auditory system in a subject (NP) suffering from repetition conduction aphasia. More specifically, the patient was asked to detect brief gaps between two stretches of broadband noise (gap detection task) and to evaluate the duration of two biphasic (WN-3) continuous noise elements, starting with white noise (WN) followed by 3 kHz bandpass-filtered noise (duration discrimination task). During the gap detection task, the two portions of each stimulus were either identical (“intra-channel condition”) or differed (“inter-channel condition”) in the spectral characteristics of the leading and trailing acoustic segments. NP did not exhibit any deficits in the intra-channel condition of the gap detection task, indicating intact auditory temporal resolution across intervals of 1–3 ms. By contrast, the inter-channel condition yielded increased threshold values. Based upon the “multiple-looks” model of central-auditory processing, this profile points at a defective integration window operating across a few tens of milliseconds – a temporal range associated with critical features of the acoustic speech signal such as voice onset time and formant transitions. Additionally, NP was found impaired during a duration discrimination task addressing longer integration windows (ca. 150 ms). Concerning speech, this latter time domain approximately corresponds to the duration of stationary segmental units such as fricatives and long vowels. On the basis of our results we suggest, that the patient’s auditory timing deficits in non-speech tasks may account, at least partially, for his impairments in speech processing.     

Kombination von Settings und Verfahren in der Psychotherapie

Literature research and own clinical experiences confirm the significance of a combined use of settings and methods in the area of inpatient and outpatient psychotherapy. For inpatient treatment, the combined use of methods, such as individual psychotherapy, group therapy, creative therapies, and sport, are an essential part of the treatment. In outpatient treatment, the regulations of the German insurance do not permit such combinations. Nevertheless, they occur and are often proactively initiated by the patients. The various combined use of psychotherapy and psychotropics is very well studied, but also the combination of settings, i.e. supplementary inpatient treatment, day treatment, and outpatient treatment have to be considered. While administering their therapies, psychotherapists should keep in mind possibly concurrently ongoing treatments as well as former therapies and their effects on the patients. With the exception of combinations with psychotropic treatment, there exist almost no empirical data in this important field.     

The influence of syllable onset complexity and syllable frequency on speech motor control

Functional imaging studies have delineated a "minimal network for overt speech production", encompassing mesiofrontal structures (supplementary motor area, anterior cingulate gyrus), bilateral pre- and postcentral convolutions, extending rostrally into posterior parts of the inferior frontal gyrus (IFG) of the language-dominant hemisphere, left anterior insula as well as bilateral components of the basal ganglia, the cerebellum, and the thalamus. In order to further elucidate the specific contribution of these cerebral regions to speech motor planning, subjects were asked to read aloud visually presented bisyllabic pseudowords during functional magnetic resonance imaging (fMRI). The test stimuli systematically varied in onset complexity (CCV versus CV) and frequency of occurrence (high-frequency, HF versus low-frequency, LF) of the initial syllable. A cognitive subtraction approach revealed a significant main effect of syllable onset complexity (CCV versus CV) at the level of left posterior IFG, left anterior insula, and both cerebellar hemispheres. Conceivably, these areas closely cooperate in the sequencing of subsyllabic aspects of the sound structure of verbal utterances. A significant main effect of syllable frequency (LF versus HF), by contrast, did not emerge. However, calculation of the time series of hemodynamic activation within the various cerebral structures engaged in speech motor control revealed this factor to enhance functional connectivity between Broca's area and ipsilateral anterior insula.     

Psychometric evaluation of the Multidimensional Assessment of Fatigue scale for use with pregnant and postpartum women

Although fatigue is a common experience for pregnant women and new mothers, few measures of fatigue have been validated for use with this population. To address this gap, the authors assessed psychometric properties of the Multidimensional Assessment of Fatigue (MAF) scale, which was used in 2 independent samples of pregnant women. Results indicated that the psychometric properties of the scale were very similar across samples and time points. The scale possesses a high level of internal consistency, has good convergent validity with measures of sleep quality and depression, and discriminates well from a measure of social support. Contrary to previous evaluations of the MAF, data strongly suggest that the scale represents a unidimensional construct best represented by a single factor. Results indicate that the MAF is a useful measure of fatigue among pregnant and postpartum women.     

The Crooked Path from Vagueness to Four-Dimensionalism

Philosophical Studies -     

Isolation and Non-Arbitrary Division: Frege's Two Criteria for Counting

In §54 of the Grundlagen, Frege advances an interesting proposal on how to distinguish among different sorts of concepts, only some of which he thinks can be associated with number. This paper is devoted to an analysis of the two criteria he offers, isolation and non-arbitrary division. Both criteria say something about the way in which a concept divides its extension; but they emphasize different aspects. Isolation ensures that a concept divides its extension into discrete units. I offer two construals of this: isolation as discreteness, i.e. absence of overlap, between the objects to be counted; and isolation as the drawing of conceptual boundaries. Non-arbitrary division concerns the internal structure of the units we count: it makes sure that we cannot go on dividing them arbitrarily and still find more units of the kind. Non-arbitrary division focuses not only on how long something can be divided into parts of the same kind; it also speaks to the way in which these divisions are made, arbitrarily or non-arbitrarily, as well as to the compositional structure of the objects divided.