The treatment of epilepsies with Convulsofin

The testing of Convulsofin carried out in 220 patients at 14 clinics over a period of six months confirms the international experience gained with valproic acid and sodium valproinate. The main field of application of Convulsofin according to the experience gained will again be the treatment of fits in generalised primary epilepsy for which it permits to carry out a monotherapy to a remarkable extent. The favourable effect of the preparation in photosensitivity could be confirmed. Also in generalised secondary epilepsy and in fits of partial epilepsy. Convulsofin is partly effective, so that it can recommended as a co-medication in the treatment of therapy-resistant forms of these epilepsies which are difficult to treat. Decrease in thrombocytes, transient increase in serum transaminases, gastrointestinal disorders, loss of hair and undesired increases in body-weight were the more frequently occurring side-effects.     

Behavioral thresholds for tones during infancy

An adaptive up-down tracking procedure was used in combination with a visually reinforced head turn response to examine auditory sensitivity for 500, 2000, and 8000-Hz tone bursts in infants 6 to 18 months of age. Six- and 10-month-old infants were tested with headphone presentation of stimuli, while 10-, 14, and 18-month-olds were tested in sound field. Infant threshold estimates for both headphone and sound field were within 15 dB of adult comparisons for all frequencies and age groups. Six-month-olds were significantly less sensitive to the 8000-Hz tone than to either of the lower frequency stimuli, but older infants demonstrated approximately equal sensitivity for all three frequencies tested.     

Glutamate as a transmitter in the CNS and its presumed significance in the pathogenesis of cerebral seizure forms--recent aspects

Glutamate is believed to be quantitatively the most outstanding of the excitatory transmitters in the CNS. Certain conformationally related analogues, e. g. kainate, N-methyl-D-aspartate, ibotenate, and homocysteate, act as glutamate agonists. The local or systemic administration of these "excitotoxic" compounds induces epileptiform activity pointing out new and deeper insights into the epileptic process. Additionally, the glutamate transmitter hypothesis is expected to give a chance of a causal comprehension for choreatic processes as well as for the mode of action of anticonvulsant and antispastic agents.     

The sociodynamogram--a contribution to the objectivization of group process

Two simple sociometric techniques for practical use are described which are derived from the data given in the sociogram. Compared with the conventional sociogram, the group rank score we use everyday therapy has the advantage that it can be published. It permits members of the group to better identify the social situations which cause specific psychic impulses. The sociogram is reserved for the therapist. In our opinion the sociodynamogram has certain advantages over both methods because it provides an insight into spheres which are inaccessible in the sociogram and group rank score.     

On the conflict between logic and belief in syllogistic reasoning

Three experiments are reported that investigate the weighting attached to logic and belief in syllogistic reasoning. Substantial belief biases were observed despite controls for possible conversions of the premises. Equally substantial effects of logic were observed despite controls for two possible response biases. A consistent interaction between belief and logic was also recorded; belief bias was more marked on invalid than on valid syllogisms. In all experiments, verbal protocols were recorded and analyzed. These protocols are interpreted in some cases as providing rationalizations for prejudiced decisions and, in other cases, as reflecting a genuine process of premise to conclusion reasoning. In the latter cases, belief bias was minimal but still present. Similarly, even subjects who focus primarily on the conclusion are influenced to an extent by the logic. Thus a conflict between logic and belief is observed throughout, but at several levels of extent.     

The effects of therapist-client age similarity on pretherapy expectations

The present study investigated the effects of similarity between psychotherapist age and client age on client's preference for a therapist, willingness to disclose, expected therapeutic climate, and perceptions of therapist competence. Similarity theory provided a rationale for the hypothesis that prospective clients would perceive a psychotherapist similar in age more favorably than a therapist dissimilar in age. Support for the hypothesis was obtained on the dimensions of client preference, willingness to disclose, and therapist competence. Also, consistent with previous research, high experienced therapists were viewed more favorably than low experienced therapists.This research is based on a doctoral dissertation submitted by Kathleen M. Tall under the direction of Michael J. Ross to Saint Louis University.     

Determinants of pride and shame: outcome, expected success and attribution

In two experiments we investigated the relationship between subjective probability of success and pride and shame. According to Atkinson (1957), pride (the incentive of success) is an inverse linear function of the probability of success, shame (the incentive of failure) being a negative linear function. Attribution theory predicts an inverse U-shaped relationship between subjective probability of success and pride and shame. The results presented here are at variance with both theories: Pride and shame do not vary with subjective probability of success. However, pride and shame are systematically correlated with internal attributions of action outcome.     

Affect and performance in simple problems

We investigate the effects of emotional mood states on solving simple pattern comparison tasks. It is assumed that the effects of mood are mediated through response biases as well as effort expenditure. Departing from these assumptions, trend hypotheses are derived for the response biases evaluated by means of a signal detection analysis, for the response latencies, and for an adequate index of the underlying ability. The data support the hypotheses, and in particular, a positive mood state is found to improve performance. The assumption of mood-dependent differences in effort expenditure provides a parsimonious and integrative account of our results, while a reduced-capacity view cannot explain the findings obtained under positive mood induction.