分离遗传与环境对儿童发展的影响：介绍一个新颖的研究方法

本文介绍一个可以用于研究遗传与环境互动的新颖方法。此研究收集了上千个4~10岁儿童的数据。这些儿童的出生都借助于不同的辅助受孕技术（Assisted Reproductive Technologies）,包括试管婴儿、精子捐赠、卵子捐赠、胚胎捐赠及代孕技术。本项目通过妇科（助孕）医院收集被试的行为数据,包括家庭互动、养育方式、父母婚姻质量、家庭成员的心理健康及经济状况等。本文选择性地介绍一些分析的结果,以彰显这种设计在分离遗传和产前产后环境对儿童发展的贡献。首先,我们比较了“助孕”儿童与“自然孕”儿童在父母冲突、父母对子女敌意以及儿童抑郁症状之间关系的异同。其次,我们比较了这两组儿童在父母抑郁症状、家庭关系质量以及儿童抑郁症状之间关系的异同。再次,本文介绍了这一可分离遗传与环境因素的研究设计。最后,我们讨论了这一设计对发展心理病干预及预防的意义     

Development and Open Trial of a Depression Preventive Intervention for Adolescents With Attention-Deficit/Hyperactivity Disorder

Adolescents with attention-deficit/hyperactivity disorder (ADHD) are at elevated risk for experiencing unipolar depressive symptoms and disorders. The current study describes the development of a behaviorally oriented depression preventive intervention tailored for adolescents with ADHD targeting variables empirically shown to mediate ADHD and depression (i.e., reward responsivity, emotion regulation, and family support). Eight adolescents with a history of ADHD and currently elevated depressive symptoms and their parents participated in an open trial of the Behaviorally Enhancing Adolescents’ Mood (BEAM) program. Adolescents and their parents reported high satisfaction with BEAM. Staff reported BEAM was easy to implement with high adherence. Following BEAM, there were significant reductions in parent-report of adolescents’ depressive symptoms and emotion regulation at posttreatment and the 6-week follow-up and adolescent-report of reward responsivity at posttreatment. Case vignettes are also provided to illustrate implementation of the BEAM program. In spite of the small sample, lack of a control group, and some discrepancies across informants, results overall support the feasibility and acceptability of the BEAM program, and suggest it has promise in reducing depressive symptoms in adolescents with ADHD.     

Demographic,Clinical, and Service Utilization Factors Associated with Suicide‐Related Visits among Alaska Native and American Indian Adults

Alaska Native and American Indian people (AN/AIs) are disproportionately affected by suicide. Within a large AN/AI health service organization, demographic, clinical, and service utilization factors were compared between those with a suicide‐related health visit and those without. Cases had higher odds of a behavioral health diagnosis, treatment for an injury, behavioral health specialty care visits, and opioid medication dispensation in the year prior to a suicide‐related visit compared to gender‐, age‐, and residence‐ (urban versus rural) matched controls. Odds of a suicide‐related visit were lower among those with private insurance and those with non‐primary care ambulatory clinic visits.     

The prematurity stereotype: Empirical evidence and implications for practice

The prematurity stereotype is defined as a set of biased beliefs about infants who are identified as having been born prematurely. This article reviews studies that have explored how this prematurity stereotype may negatively influence adults' perceptions of, expectations for, and behavior toward premature infants. The findings from these studies are considered in the context of more general knowledge about how expectations can influence behavior and result in self-fulfilling prophecies. Recent research designed to investigate how prematurity stereotyping can be reduced also is described and evaluated. Finally, the implications of this program of research for intervention with parents of premature infants and suggestions for future research directions are discussed.     

Can Semantics Guide Ontology?

Since the linguistic turn, many have taken semantics to guide ontology. Here, I argue that semantics can, at best, serve as a partial guide to ontological commitment. If semantics were to be our guide, semantic data and semantic treatments would need to be taken seriously. Through an examination of plurals and their treatments, I argue that there can be multiple, equally semantically adequate, treatments of a natural language theory. Further, such treatments can attribute different ontological commitments to a theory. Given this, I argue that semantics can fail to deliver determinate ontological commitments and determinate answers to ontological questions, more generally.     

The Genetic Counselor in the Pediatric Arrhythmia Clinic: Review and Assessment of Services

There are minimal data on the impact of genetic counselors in subspecialty clinics, including the pediatric arrhythmia clinic. This study aimed to describe the clinical encounters of a genetic counselor integrated into a pediatric arrhythmia clinic. In the 20 months between July 2015 and February 2017, a total of 1914 scheduled patients were screened for indications relevant for assessment by a genetic counselor. Of these, the genetic counselor completed 276 patient encounters, seeing 14.4% of all patients in clinic. The most expected and common indications for genetic counselor involvement were related to suspicion for primary heritable arrhythmia conditions, though patients seen in this clinic display a wide range of cardiac problems and many additional indications for genetic evaluation were identified. Roughly 75% (211/276) of encounters were for personal history of confirmed/suspected heritable disease, including cardiac channelopathies, cardiomyopathies, ventricular arrhythmias, and congenital heart defects, and 25% (65/276) were for family history of disease, including long QT syndrome and sudden unexplained death. Overall, this study shows that about 1 in 7 patients seen in a pediatric arrhythmia clinic have indications that likely benefit from genetic counselor involvement and care. Similar service delivery models embedding genetic counselors in pediatric arrhythmia clinics should be encouraged, and this model could be emulated to increase patient access to genetic counseling services.     

An Online Investigation of Imagery to Attenuate Paranoia in College Students

Onset of psychosis typically occurs in young adulthood, and is likely to be preceded by anxiety, low mood, suspiciousness and perceptual anomalies. Where these develop into mild or brief psychotic experience, and impact on functioning, young people are identified as being at risk of psychosis. Early intervention may reduce severity or delay transition to psychosis, and yield significant healthcare cost savings. This study examined the impact of an online attachment-based imagery task on paranoia, anxiety, mood and self-esteem, in college students. An experimental design was used to compare the effects of secure and anxious-ambivalent attachment imagery. A total of 301 college students, aged 18–48 years (M?=?20.1, SD?=?2.976), were randomly assigned to one of the two imagery conditions, and assessed pre and post imagery task on standardised measures of paranoia, anxiety, mood and self-esteem. A series of mixed model analyses of variance showed that participants in the secure attachment imagery condition reported lower levels of paranoia, anxiety and negative mood, and higher levels of positive mood and self-esteem, compared with those in the anxious-ambivalent attachment imagery condition. The study is limited by the lack of a neutral control condition and follow-up measures. Nevertheless, study demonstrated the impact of attachment-based imagery on paranoia. If these effects are replicated with ‘at risk mental state’ groups, and maintained at follow-up, online imagery may provide a safe and highly accessible means of attenuating paranoia in young people at risk of developing psychosis.