What Information Do Cancer Genetic Counselees Prioritize?

This study explored the informational needs of individuals attending genetic counseling for hereditary cancer, using a free-choice and a forced choice method. Prior to the consultation the informational needs of 334 counselees from Sweden and Norway were assessed by the QUOTE-gene (ca) questionnaire and by a study specific forced choice method, using Q-methodology. Questionnaire responses indicated that counselees' major concerns pertained to the need to be taken seriously, to be provided with sufficient risk estimation and medical/genetic information and to be involved in the decision making process. Furthermore, prior to counseling, counselees noted that the counselors' consideration and skillfulness were also extremely important. Analysis of the Q-sorting results revealed that counselees' needs could be assigned to one of five groups: the "need for facts; caring communication and medical information; information and support in communicating the genetic information to others; practical care and practical/medical information". Particularly noteworthy, counselees with varying backgrounds characteristics prioritized different needs. Cancer genetic counselees probably have different needs due to their medical and demographic background when attending genetic counseling. Addressing counselees' specific concerns more sufficiently and thereby increasing the overall effectiveness of the counseling session requires increased insight into individual needs, by for instance, utilizing screening methods such as QUOTE-gene (ca) prior to the counseling session.     

Consolidation and translation regulation

mRNA translation, or protein synthesis, is a major component of the transformation of the genetic code into any cellular activity. This complicated, multistep process is divided into three phases: initiation, elongation, and termination. Initiation is the step at which the ribosome is recruited to the mRNA, and is regarded as the major rate-limiting step in translation, while elongation consists of the elongation of the polypeptide chain; both steps are frequent targets for regulation, which is defined as a change in the rate of translation of an mRNA per unit time. In the normal brain, control of translation is a key mechanism for regulation of memory and synaptic plasticity consolidation, i.e., the off-line processing of acquired information. These regulation processes may differ between different brain structures or neuronal populations. Moreover, dysregulation of translation leads to pathological brain function such as memory impairment. Both normal and abnormal function of the translation machinery is believed to lead to translational up-regulation or down-regulation of a subset of mRNAs. However, the identification of these newly synthesized proteins and determination of the rates of protein synthesis or degradation taking place in different neuronal types and compartments at different time points in the brain demand new proteomic methods and system biology approaches. Here, we discuss in detail the relationship between translation regulation and memory or synaptic plasticity consolidation while focusing on a model of cortical-dependent taste learning task and hippocampal-dependent plasticity. In addition, we describe a novel systems biology perspective to better describe consolidation.     

Physical activity and psychological benefits: A position statement from the international society of sport psychology

This study explores nonverbal behaviors in the form of gestures and touch during elite handball matches. Based on a coding scheme, 616 postshot periods following a goal, stemming from 18 matches, were analyzed. Results revealed that, on average, 2.77 nonverbal behaviors were displayed after scoring. Play-off matches resulted in a higher average of nonverbal behaviors than league matches. The more a team was leading by, the higher the overall number of nonverbal behaviors; meanwhile, the overall amount of nonverbal behaviors declined over the course of a match. The results pinpoint to the situation specificity of nonverbal behaviors during ongoing matches.     

Cross-sectional and longitudinal confirmatory factor models for the german test anxiety inventory: A construct validation

Construct validity of the German Test Anxiety Inventory (TAI-G) was tested in two respects. Firstly, the purported four-dimensional structure of the TAI-G (comprising subscales Emotionality, Worry, Interference, and Lack of Confidence) as well as relations of the test anxiety dimensions to self-efficacy were tested. Secondly, the trait conception of the TAI-G was tested within the framework of Latent State-Trait theory. The TAI-G was given to a student sample (N=302) on three occasions with a time interval of 2 weeks along with a study-specific self-efficacy scale on occasion 1. Dimensionality assumptions as well as relations with self-efficacy were tested using cross-sectional second-order confirmatory factor analysis. The trait conception was tested separately for TAI-G subscales by specifying longitudinal confirmatory factor models (Latent State-Trait models) and by calculating variance proportions of manifest variables (Latent State-Trait coefficients) referring to different sources of systematic variance (person, situation, and method) based on parameter estimates of the models. Results were supportive of both the purported four-dimensional structure and hypothesized relationships to self-efficacy (i.e., acceptable model fit) as well as of the trait conception of test anxiety (i.e., acceptable model fit and high proportion of variance due to person component). Implications for further validation studies were discussed.     

Learning influences the encoding of static and dynamic faces and their recognition across different spatial frequencies

Studies on face recognition have shown that observers are faster and more accurate at recognizing faces learned from dynamic sequences than those learned from static snapshots. Here, we investigated whether different learning procedures mediate the advantage for dynamic faces across different spatial frequencies. Observers learned two faces—one dynamic and one static—either in depth (Experiment 1) or using a more superficial learning procedure (Experiment 2). They had to search for the target faces in a subsequent visual search task. We used high-spatial frequency (HSF) and low-spatial frequency (LSF) filtered static faces during visual search to investigate whether the behavioural difference is based on encoding of different visual information for dynamically and statically learned faces. Such encoding differences may mediate the recognition of target faces in different spatial frequencies, as HSF may mediate featural face processing whereas LSF mediates configural processing. Our results show that the nature of the learning procedure alters how observers encode dynamic and static faces, and how they recognize those learned faces across different spatial frequencies. That is, these results point to a flexible usage of spatial frequencies tuned to the recognition task.     

Work–family conflict and facilitation: The combined influence of the job demand–control model and achievement striving

This study investigated the moderating effect of achievement striving (AS) on the relationship between situational variables, defined by the Job Demand–Control model (JDC), and both work–family conflict and work–family facilitation. In a sample of 224 employees in the welfare sector, the results of two hierarchical regression analyses showed that job demands were significantly positively related and job control was significantly negatively related to work–family conflict but not to work–family facilitation. For AS, a significant positive relationship was found with both work–family conflict and work–family facilitation. Interactions between situational variables and AS were insignificant although the interaction between AS and job control on work–family facilitation was close to significance in line with the expectations. Specifically, a lower level of job control did not lower the level of WFF experienced by individuals high on AS. Theoretical and practical implications are discussed.     

Influence of Attachment Style on Major Psychological Capacities to Lead

Addressing psychological literature's deficiency in research on the early development of leaders in everyday life (e.g., leaders in the workplace, leaders in social settings, leaders in organizational settings), this study assumed that central psychological capacities required for such leaders can be predicted and explained by J. Bowlby's (1969) Bowlby, J. 1969. Attachment and loss: Vol. 1. Attachment New York : Basic Books. [Google Scholar] attachment theory concerning developmental processes in infancy. The authors administered a series of questionnaires to 402 participants. The authors analyzed data by using structural equation modeling. Findings indicate a potential-to-lead construct that forms in infancy. The results fully supported the authors’ main arguments: that secure attachment style influences the potential to lead and that this capacity is essential for leadership as measured by leadership ranking.     

The Epistemic Challenge of Hearing Child’s Voice

Classical conceptual distinctions in philosophy of education assume an individualistic subjectivity and hide the learning that can take place in the space between child (as educator) and adult (as learner). Grounded in two examples from experience I develop the argument that adults often put metaphorical sticks in their ears in their educational encounters with children. Hearers’ prejudices cause them to miss out on knowledge offered by the child, but not heard by the adult. This has to do with how adults view education, knowledge, as much as child, and is even more extreme when child is also black. The idea is what Miranda Fricker calls ‘epistemic injustice’ which occurs when someone is wronged specifically in their capacity as a knower. Although her work concerns gender and race, I extrapolate her radical ideas to (black) child. Awareness of the epistemic injustice that is done to children and my proposal for increased epistemic modesty and epistemic equality could help transform pedagogical spaces to include child subjects as educators. A way forward is suggested that involves ‘cracking’ the concept of child and a different non-individualised conception of education.     

Human freezing in response to affective films

Human freezing has been objectively assessed using a passive picture viewing paradigm as an analog for threat. These results should be replicated for other stimuli in order to determine their stability and generalizability. Affective films are used frequently to elicit affective responses, but it is unknown whether they also elicit freezing-like defense responses. To test whether this is the case, 50 participants watched neutral, pleasant and unpleasant film fragments while standing on a stabilometric platform and wearing a polar band to assess heart rate. Freezing-like responses (indicated by overall reduced body sway and heart rate deceleration) were observed for the unpleasant film only. The unpleasant film also elicited early reduced body sway (1–2 s after stimulus onset). Heart rate and body sway were correlated during the unpleasant film only. The results suggest that ecologically valid stimuli like films are adequate stimuli in evoking defense responses. The results also underscore the importance of including time courses in human experimental research on defense reactions in order to delineate different stages in the defense response.