FDA儿童药物临床试验规范化对我国的启示

对美国食品药品监督管理局（Food and Drug Administration,FDA）儿童药物临床试验的规范化进行界定,发现我国面临儿童用药方面存在安全隐患、儿童药物临床试验存在需求缺口、儿童药物临床试验审查不够规范等现实困境,引发规范儿童药物临床试验的关键性思考。借鉴FDA对儿童药物临床试验的规范化实践,总结FDA儿童药物临床试验相关法案、临床试验指南文件以及对伦理审查委员会的监管措施,得出完善儿童药物临床试验专门法规和指南、加强相关伦理委员会监管和指导、规范儿童药物临床试验伦理审查、加大儿童受试者保护力度等对我国的启示。

     

国内外预立医疗照护计划社会经济效益的探讨

从卫生经济学视角,探讨预立医疗照护计划的社会经济效益。通过分析预立医疗照护计划的卫生经济政策、经济分析模式及社会经济效益评价研究等发现,预立医疗照护计划具有较明显的社会经济效益。借鉴国外经验和结合我国文化背景提出预立医疗照护计划在我国发展的对策和建议,包括建立相关政策突破发展障碍;构建激励制度,加强人才培养以支撑预立医疗照护计划发展;开展评价预立医疗照护计划经济效益的研究,以价值为导向构建本土化的医疗模式,以期为我国发展预立医疗照护计划的卫生经济学研究领域提供理论依据。

     

视觉形状知觉在近似数量系统和计算流畅性关系中的作用

已有大量研究揭示了近似数量系统与计算流畅性的相关关系, 但缺少对二者关系原因的系统检验与论证。视觉形状知觉假设有别于传统的数量领域特异性解释, 认为对形状的快速知觉是近似数量系统与计算流畅性的共同认知机制, 即视觉形状的快速知觉能力可以解释二者之间的相关关系。近似数量系统和计算流畅性在加工过程中依赖对形状的快速知觉, 二者在加工过程中都涉及了复杂视觉刺激的快速处理。视觉形状知觉假设得到了一系列研究结果的支持, 但局限在视觉形状知觉与二者关系的探讨上, 视觉形状知觉在二者关系中作用的加工机制仍不清楚。未来研究需要结合多种研究方法和技术, 多角度深入探讨视觉形状知觉在二者关系中作用的认知与脑机制, 并将研究结果应用于数学课堂教学和计算困难的干预中。     

What the voice reveals: within- and between-category stereotyping on the basis of voice

The authors report research that attempts to shift the traditional focus of visual cues to auditory cues as a basis for stereotyping. Moreover, their approach examines whether gender-signaling vocal cues lead not only to between-category but also to within-category gender stereotyping. Study 1 showed that both men and women vary within category in how feminine their voices sound and that perceptions of vocal femininity are highly consensual. Furthermore, the measured acoustic characteristics that differed between gender were also related to perceptions of within-gender femininity. Subsequent studies demonstrated that variability in vocal femininity affects gender stereotyping when the targets are all of the same gender (Study 2) and when the targets are of different genders (Study 3). In the latter case, evidence of both category-based and feature-based stereotyping was found. Mediation analyses showed that the relationship between acoustics and stereotyping was in part due to femininity.     

日本对自杀的心理学研究

20世纪 50年代以来 ,日本青少年自杀率急剧上升 ,为了更好地实施危机干预 ,日本学者对自杀行为进行了广泛的研究。研究呈现出由关注宏观的社会因素转向更加关注个体的心理和个性特征的趋势 ,取得了一些很有价值的研究成果。本文综述了日本学者对自杀的内涵、分类、年龄特征、性别特征、动机、手段、自杀前的心理特征和自杀预防的研究成果。     

Well-being of mothers of children with mental retardation: An evaluation of the Double ABCX model in a cross-cultural context

The present study was designed to compare the psychological well-being of mothers of children with mental retardation in the USA and Korea. The Double ABCX model of stress proposed by McCubbin and Patterson (1983) was evaluated for the two national groups. Thirty-eight American and 40 Korean mothers participated in the home-visit interview. The path models in the present study partially supported the ABCX model, but different path models for the two national groups provided important explanations for the well-being of mothers from the two nations. The cause of stress for the American mothers was specific to the individual variables. For Korean mothers, cultural values that carry social influence were more strongly associated with their attitudes towards the child and their experience of stress.     

家庭文化资本对幼儿数学学习的影响

本研究对来自上海市的590个中、大班幼儿家庭进行问卷调查,旨在了解家庭文化资本对幼儿数学学习的影响。结果表明：作为家庭客体化文化资本的家庭文化环境和作为家庭身体化文化资本的幼儿家长数学教导信念对幼儿的家庭数学学习经验有直接的影响作用;作为家庭制度化文化资本的家庭教育背景则通过家庭文化环境和幼儿家长的数学教导信念对幼儿家庭数学学习经验有间接的影响作用。     

塞辅音和声调知觉问题

本文报告的两个实验以合成的汉语普通话CV音节作刺激,研究了塞辅音与声调之间在知觉上的相互作用问题。主要结果是:(1)塞辅音的发音方式影响声调的知觉,不送气音使听者在辨别声调时倾向于基频曲线起点高的声调反应;(2)音节的声调也影响对塞音发音方式的判断,在一、四声音节里,听者倾向于将塞辅音听成不送气音,在二、三声音节里,听成送气音。     

Differences in the micromechanical properties of dendrites and interdendritic regions in superalloys

Statistical analysis of white-light interferometry (WLI) experiments performed on Ni-based single-crystal superalloys (SX) have revealed a different height distribution between the dendritic cores (DCs) and the interdendritic regions (IRs) of the polished samples. The micromechanical property difference is largely ascribed to the uneven distribution of the alloying elements. In this context, possible reasons for this difference are discussed by comparing with different experiment results obtained by previous researchers, and a proposal forecasting the hardness ratio of IRs/DCs is put forward.     

在综合基础上创新——鼠伤寒菌pla基因及其功能研究的思考

鼠伤寒菌pla基因及功能的研究从课题确立到取得结果整个过程,充分展现了综合研究方法在现代科学研究中的重要作用;在综合基础上的创新是科学研究成功的中心环节。