临床试验中的利益冲突：伦理和政策问题

人们对于研究人员、赞助商和研究机构三者之间的经济利益关系给予越来越多的关注,人体试验研究中的经济利益与其他利益有所不同,这种经济利益会导致偏见或诱导不正当的行为,尤其是当有从研究中获益的机会存在时,将会影响到研究人员关于应该选择哪个受试者,应该提供给受试者什么样的医疗服务,甚至应该如何正确使用受试者保密的健康信息方面的判断,由经济利益引起的明显的风险同样也会威胁公众的学术机构研究使命的支持,从处理临床试验中利益冲突的准则,什么样的经济利益是研究中的重大经济利益。准则的实施等方面进行了详尽的叙述,最后指出没有潜在受试者和公众的信任,我们就不能有效地开展研究。     

The effects of perceived phenotypic racial stereotypicality and social identity threat on racial minorities’ attitudes about police

This study examines the role of perceived phenotypic racial stereotypicality and race-based social identity threat on racial minorities’ trust and cooperation with police. We hypothesize that in police interactions, racial minorities’ phenotypic racial stereotypicality may increase race-based social identity threat, which will lead to distrust and decreased participation with police. Racial minorities (Blacks, Latinos, Native Americans, and multi-racials) and Whites from a representative random sample of city residents were surveyed about policing attitudes. A serial multiple mediation model confirmed that racial minorities’ self-rated phenotypic racial stereotypicality indirectly affected future cooperation through social identity threat and trust. Due to the lack of negative group stereotypes in policing, the model did not hold for Whites. This study provides evidence that phenotypic stereotypicality influences racial minorities’ psychological experiences interacting with police.     

Explaining the Inexplicable: Differences in Attributions for the Holocaust in Germany,Israel, and Poland

Seventy years have passed since the Holocaust, but this cataclysmic event continues to reverberate in the present. In this research, we examine attributions about the causes of the Holocaust and the influence of such attributions on intergroup relations. Three representative surveys were conducted among Germans, Poles, and Israeli Jews to examine inter‐ and intragroup variations in attributions for the Holocaust and how these attributions influence intergroup attitudes. Results indicated that Germans made more external than internal attributions and were especially low in attributing an evil essence to their ancestors. Israelis and Poles mainly endorsed the obedient essence attribution and were lowest on attribution to coercion. These attributions, however, were related to attitudes towards contemporary Germany primarily among Israeli Jews. The more they endorsed situationist explanations, and the less they endorsed the evil essence explanation, the more positive their attitude to Germany. Among Germans, attributions were related to a higher motivation for historical closure, except for the obedience attribution that was related to low desire for closure. Israelis exhibited a low desire for historical closure especially when attribution for evil essence was high. These findings suggest that lay perceptions of history are essential to understanding contemporary intergroup processes.     

To Hook Up or Date: Which Gender Benefits?

Hooking up on college campuses has become more frequent than dating in heterosexual sexual interaction. Analysis of the relative benefits and costs associated with dating and hooking up suggest that women benefit more from dating while men benefit more from hooking up. U.S students (150 women, 71 men) at a midsized southeastern university indicated preferences for dating and hooking up across a number of situations and indicated the perceived benefits and risks associated with each. As hypothesized, in most situations women more than men preferred dating and men more than women preferred hooking up. Both genders perceived similar benefits and risks to dating and hooking up; differences provided insight into the sexual motives of college women and men.     

A multi‐component approach to the treatment of chronic rumination

A multi‐component intervention was used to treat chronic rumination exhibited by an adult female diagnosed with a developmental disability. The intervention consisted of: (a) interruption of precursor behavior, (b) the alternation of 10‐min periods of continued instruction that involved walking and working with (c) 10‐min periods in which instructions were not delivered but a variable time 5‐s schedule of noncontingent attention was programmed, and (d) a 1‐min differential reinforcement of other behavior (DRO) schedule. During the intervention, rumination decreased by 82% relative to baseline. Next, components of the multi‐component intervention were systematically removed to evaluate their individual contribution. Results suggested that each individual component contributed to the overall treatment effects. Copyright © 2010 John Wiley & Sons, Ltd.     

Maternal Distress and Parenting in the Context of Cumulative Disadvantage

To read this article's abstract in both Spanish and Mandarin Chinese, please visit the article's full‐text page on Wiley InterScience ( http://interscience.wiley.com/journal/famp ). This article presents an emergent conceptual model of the features and links between cumulative disadvantage, maternal distress, and parenting practices in low‐income families in which parental incarceration has occurred. The model emerged from the integration of extant conceptual and empirical research with grounded theory analysis of longitudinal ethnographic data from Welfare, Children, and Families: A Three‐City Study. Fourteen exemplar family cases were used in the analysis. Results indicated that mothers in these families experienced life in the context of cumulative disadvantage, reporting a cascade of difficulties characterized by neighborhood worries, provider concerns, bureaucratic difficulties, violent intimate relationships, and the inability to meet children's needs. Mothers, however, also had an intense desire to protect their children, and to make up for past mistakes. Although, in response to high levels of maternal distress and disadvantage, most mothers exhibited harsh discipline of their children, some mothers transformed their distress by advocating for their children under difficult circumstances. Women's use of harsh discipline and advocacy was not necessarily an “either/or” phenomenon as half of the mothers included in our analysis exhibited both harsh discipline and care/advocacy behaviors. Maternal distress characterized by substance use, while connected to harsh disciplinary behavior, did not preclude mothers engaging in positive parenting behaviors.     

A Dyadic Analysis of the Between‐ and Within‐System Alliances on Distress

To read this article's abstract in both Spanish and Mandarin Chinese, please visit the article's full‐text page on Wiley InterScience ( http://interscience.wiley.com/journal/famp ). This study examines the relationship between the therapeutic alliance and distress using the couple rather than the individual as the unit of analysis. One hundred and seventy‐three couples receiving treatment for relational distress at two university clinics participated in this study. The actor–partner interdependence model was used to analyze the relationship of each partner's between‐ and within‐system alliance scores and distress at session four. Results provide support for actor effects on relational distress for both male and female partners and for actor effects on psychological distress for female partners. Limited support was found for partner effects on distress. Furthermore, results indicate that the alliance between partners is a stronger predictor of improvement in early sessions in comparison with the alliance between the individual and the therapist.