Increases in blood glucose levels after epinephrine injection appear to contribute to the hormone's effects on learning and memory. The present experiment evaluated whether epinephrine-induced enhancement of spontaneous alternation performance would be attenuated in fasted rats that had blunted increases in circulating glucose levels after injections of epinephrine. Rats deprived of food for 24 h prior to injection of epinephrine exhibited significant attenuation of the increase in blood glucose levels seen in fed rats. When the rats were tested on a delayed spontaneous alternation task, epinephrine enhanced performance in fed rats but not in rats deprived of food for 24 h. These findings are consistent with the view that hyperglycemia subsequent to epinephrine injections contributes to the memory-enhancing effects of epinephrine. 相似文献
Epidemiology is a core science of public health, focusing on research related to the distribution and determinants of both
positive and adverse health states and events and on application of knowledge gained to improve public health. The American
College of Epidemiology (ACE) is a professional organization devoted to the professional practice of epidemiology. As part
of that commitment, and in response to concerns for more explicit attention to core values and duties of epidemiologists in
light of emerging issues and increased scrutiny of epidemiology, the College developed, adopted, and published a set of Ethics
Guidelines. The structure of the ACE ethics guidelines is in four parts: (1) a brief statement of core values and duties of
epidemiologists, coupled with the virtues important to professional practice; (2) concise statements of key duties and obligations;
(3) exposition of the duties and obligations with more applications; and (4) a brief summary and conclusion. The Guidelines
have been published on the ACE website and in the official College journal Annals of Epidemiology. The guidelines contain (and maintain) core elements that define the discipline of epidemiology and its fundamental duties,
but they are also intended to be dynamic and evolving, responsive to a changing professional and social environment.
An earlier version of this paper was presented at the AAAS-Office of Research Integrity (ORI) meeting in Washington DC on
the theme: “The Role and Activities of Scientific Societies in Promoting Research Integrity” held on April 10–11, 2000.
Affiliations of co-authors: Douglas L. Weed, MD, MPH, PhD is Director of the Cancer Prevention Fellowship Program, Office
of Preventive Oncology, National Cancer Institute; Jeffrey P. Kahn, PhD, MPH, is Professor of Medicine and Director of the
Center for Bioethics, UMN Twin Cities, Minneapolis; Michael A. Stoto, PhD, is Associate Director for Public Health, RAND Center
for Domestic and International Health Security, Arlington, VA. 相似文献
Within-person studies of emotional disclosure have found evidence of a disclosure-discordance effect of depression, whereby the positive association between the intensity of one’s emotional experience and verbal disclosure of that experience weakens with increasing depression symptoms. Because these previous studies have exclusively been naturalistic ones, we examined the disclosure-discordance effect of depression in the lab. Participants (N?=?115) completed a measure of depression symptoms and viewed a series of emotionally evocative photographs. Emotion-expressive behavior while viewing each photograph was rated by judges, subjective emotional experience was assessed via self-report, and emotional disclosure just after the photograph was viewed was rated by different judges. Multilevel analyses indicated that depression symptoms moderated the association between the behavioral (i.e., facial) expression of emotion intensity and disclosure of emotion. Moderation was not supported in analyses with self-reported emotional intensity as a predictor. These findings partly supported the disclosure-discordance effect, and they inform methods of empirically examining the effect of depression symptoms on the verbal disclosure of emotion.
The stated goal of protecting White women from harm has been used, historically and contemporarily, as a pretext for racial violence. Two studies explored the relationship between protective paternalism (the belief that men should protect and care for women—part of benevolent sexism; Glick and Fiske 1996) and anti-minority racial attitudes. In Study 1 (n = 474, 61% women, 61% White), survey data found that protective paternalism was related to anti-Black bias, but only for White respondents. Study 2 (n = 242, 52% women, 74% White) experimentally manipulated feelings of threat to test for increases in protective paternalism and its corresponding effect on three anti-minority racial attitudes. For male participants only, threat (i.e., reading about recent increases in violent crime) increased endorsement of protective paternalism, which was in turn associated with a more negative view of immigration, and, for White men only, less support for policies that benefit racial minority groups and greater denial of racial bias in policing. Threat did not increase protective paternalism in female participants. For White men in particular, news of crime and danger increases racial bias by first increasing the desire to protect women. Policymakers should be aware that framing policies around safety concerns or appealing to the protection of women might unintentionally bolster anti-minority racial prejudices. 相似文献
In a population-based sample of 112 nine-year old twin pairs, we investigated the association among total brain volume, gray matter and white matter volume, intelligence as assessed by the Raven IQ test, verbal comprehension, perceptual organization and perceptual speed as assessed by the Wechsler Intelligence Scale for Children-III. Phenotypic correlations between the brain volumes and intelligence traits ranged between .20 and .33. Processing speed and brain volume did not correlate. The relation between brain volume and intelligence was entirely explained by a common set of genes influencing both sets of phenotypes. 相似文献
The widely and internationally replicated socioeconomic status (SES) gradient of executive function (EF) implies that intervention approaches may do well to extrapolate conditions and practices from contexts that generate better child outcomes (in this case, higher SES circumstances) and translate these to contexts with comparatively poorer outcomes (often low‐SES populations). Yet, can the reverse also be true? Using data from equivalent assessments of 1,092 pre‐schoolers’ EFs in South Africa and Australia, we evaluated: the SES gradient of EF within each sample; and whether this SES gradient extended cross‐culturally. The oft‐found EF‐SES gradients were replicated in both samples. However, contrary to the inferences of EF‐SES associations found nationally, the most highly disadvantaged South African subsample outperformed middle‐ and high‐SES Australian pre‐schoolers on two of three EFs. This suggests the possibility of EF‐protective and ‐promotive practices within low‐ and middle‐income countries that may aid understandings of the nature and promotion of EFs. 相似文献