Non-interaction of ventromedial and lateral hypothalamic mechanisms in the regulation of feeding and hoarding behaviour in the rat

Lesions of the hypothalamic ventromedial nucleus (VMN) led to an immediate increase in food intake but not to any increase in hoarding activity. Later, when subjects were very obese, they failed to hoard even in response to a 16-hr. deprivation schedule, although this schedule did produce hoarding if body weights were held at, or were brought down to, preoperative levels. These results indicate that the lateral hypothalamic mechanism responsible for hoarding and feeding responds to long-term nutritional factors, and that it is not directly affected by the short-term satiety mechanisms in the VMN. These findings support the hypothesis (a) that even “non-physiological” activities (e.g. hoarding, exploration) are motivated by physiological needs, and (b) that the reason these activities do not ordinarily covary with physiological drives is that, unlike the physiological drives, they are not subject to inhibition by the hypothalamic satiety mechanisms.     

The role of response processes in the formation of cross-modality assimilation effects

A unimanual, two-digit choice-reaction-time task was used in conjunction with visual signals presented in the extreme peripheral field. The position of the signal on the retina, the eye stimulated, the hand used in responding, and the operating digits were all controlled for their effects. Stimulus-response compatibility was maintained throughout. It was found that RT to ipsilateral S-R pathways was consistently faster than when the pathways involved transcommissural connections. Subsidiary findings related to differences between the operating digits and the side of signal occurrence. These effects are discussed in connection with known interhemispheric phenomena and other CRT findings.     

A suit for protecting chronically implanted devices in monkeys

The plastic barrel suit provides complete protection of chronically implanted fistulas and electrical connectors. The lost time, expense, and the frustrations of having these devices damaged was avoided.     

Visual on- and off-latencies and handedness

Ten Ss served in this experiment, five right-handed and five left-handed. Every S was tested in a perceived-order situation and by the up-and-down method to determine the relative on-latency for a visual test stimulus. i.e, (ON-Lat for lest stimulus involving right hemisphere- ON-Lat for standard stimulus involving left hemisphere) and to determine a similarly defined relative off-latency for the same test stimulus. The algebraic difference between the relative on-latency measure and the relative off-latency measure was then found. Data from a previous study had suggested that this “on-off difference” was characteristically positive for left-handed Ss and negative for right-handed Ss. The present data agree. The left-handed Ss were found to differ significantly from the right-handed Ss in the magnitude of the on-off difference. This outcome appears important as a possible clue to functional interhemispheric differences related to handedness.     

Two-key concurrent responding: response-reinforcement dependencies and blackouts

Two-key concurrent responding was maintained for three pigeons by a single variable-interval 1-minute schedule of reinforcement in conjunction with a random number generator that assigned feeder operations between keys with equal probability. The duration of blackouts was varied between keys when each response initiated a blackout, and grain arranged by the variable-interval schedule was automatically presented after a blackout (Exp. I). In Exp. II every key peck, except for those that produced grain, initiated a blackout, and grain was dependent upon a response following a blackout. For each pigeon in Exp. I and for one pigeon in Exp. II, the relative frequency of responding on a key approximated, i.e., matched, the relative reciprocal of the duration of the blackout interval on that key. In a third experiment, blackouts scheduled on a variable-interval were of equal duration on the two keys. For one key, grain automatically followed each blackout; for the other key, grain was dependent upon a response and never followed a blackout. The relative frequency of responding on the former key, i.e., the delay key, better approximated the negative exponential function obtained by Chung (1965) than the matching function predicted by Chung and Herrnstein (1967).     

Choice for periodic schedules of reinforcement

Pigeons' responses in the presence of two concurrently available (initial-link) stimuli produced one of two different (terminal-link) stimuli according to identical but independent variable-interval schedules. Responding in the mutually exclusive terminal links was reinforced with food according to fixed-ratio schedules for six pigeons and according to fixed-interval schedules for two pigeons. None of the pigeons matched the proportion of (choice) responses in the initial links to the proportion of the rates of reinforcement obtained during the terminal links. Instead, as the values of each of the terminal-link schedules were increased by a constant amount, the choice proportions for the stimulus associated with the smaller of the two values increased, even though the relative rates of reinforcement during the terminal links decreased. These results are incompatible with those from previous studies with aperiodic (variable-interval or variable-ratio) schedules. The present results do suggest, however, that in transforming aperiodic schedules into their periodic equivalents, it may be necessary to consider the size of the smallest interreinforcement interval comprising the terminal-link schedules.     

Some punishing effects of response-force

The present experiment explored the punishing effect of different response-force requirements by means of a two-operant design analogous to a two-component chain schedule. The first component of the chain required a lever pull through 0.25 in. (0.64 cm) at 1 lb (4.45 N) of force. The second component required a lever pull through an additional 0.75 in. (1.90 cm) with the force varied between sessions from 1 lb to 50 lb (4.45 N to 223 N). Completion of the second component of the chain was reinforced after variable intervals averaging 1 min. The average rate of first-component response decreased as the force requirement for second-component responses was increased. This rate reduction did not appear to be due to increased response duration, “fatigue”, or differing rates of reinforcement. If the force requirement for the second-component response is viewed as a consequence for the first-component response, then the results of the experiment show that a high force requirement is a punisher.