微流控分析芯片在循环肿瘤细胞检测中的运用

随着人们对于肿瘤性疾病的发生、发展、转移机制的进一步探索,循环肿瘤细胞（CTCs）逐渐进入人们视野,其应用价值日益体现,可用于肿瘤性疾病的早期诊断及治疗效果的监测,尤其是对于早期肿瘤的诊断具有独特优势。其富集技术及检测方法也在发生着日新月异的变化。近年来,微流控分析芯片技术运用于 CTCs 的富集及检测,具有高丰度、高富集度、高活性及不需要对样本进行预处理等优点使得人们聚焦于此技术,本文对微流控分析芯片在 CTCs 检测中的运用做简要综述。     

情绪效价与面孔类型对幼儿无意视盲的影响

幼儿对不同的情绪面孔图片存在不同的注意偏向,考察情绪效价与面孔类型对幼儿无意视盲的影响,可以帮助我们进一步认识幼儿对情绪面孔的注意偏向。本研究采用静态无意视盲的实验范式,通过2（面孔类型：符号化卡通、真人）×2（情绪效价：积极、消极）被试间完全随机设计,考察了111名幼儿（62.5±3.6个月,男生60名）在无意注意条件下对不同情绪效价和不同类型面孔的觉察情况。结果表明：（1）幼儿对积极情绪面孔的觉察率显著高于消极情绪面孔;（2）符号化卡通面孔与真人面孔的整体觉察率不存在显著差异;（3）积极情绪面孔中符号化卡通面孔的觉察率高于真人面孔。综上,情绪效价对无意视盲的影响会基于面孔类型的不同而不同,幼儿对卡通积极情绪面孔有更显著的注意偏向。     

母亲元情绪理念与学前儿童社会适应的相互作用关系

采用追踪设计对438名学前儿童母亲进行问卷调查研究,主要探讨了母亲元情绪理念与学前儿童社会适应的相互作用关系。交叉滞后分析结果表明：（1）相邻两次测量的母亲各元情绪理念之间,社会适应各指标之间均具有中等程度的稳定性;（2）同一时间点的母亲各元情绪理念与儿童社会适应各指标之间均显著相关;（3）母亲元情绪理念与儿童社会适应之间部分存在着相互作用关系：控制了变量自身的连续性后,前测的母亲情绪教导显著正向预测后测的儿童敏感合作;前测的母亲情绪不干涉显著正向预测后测的儿童愤怒攻击、焦虑退缩行为;反过来,前测的儿童敏感合作能正向预测后测的母亲情绪教导,显著负向预测情绪不干涉、情绪摒除和情绪紊乱;前测的焦虑退缩能显著正向预测后测的母亲情绪摒除和情绪紊乱。     

Parental Health and Children’s Functioning in Immigrant Families: Family Roles and Perceived Treatment at School

Although parents’ health condition is generally thought to be related to their involvement in their children’s functioning, the possible dynamics behind the scenes in school contexts with immigrant children has received little attention. This study examined the association between parents’ health condition and their children’s academic and behavioral functioning, as well as the mediation effects of parents’ school engagement and children’s perceived treatment at school among 607 immigrant families with 10- to 12-year-old children. Using structural equation modeling, the results indicated that parents’ poor health condition was associated with children’s increased behavioral problems. Parents’ school engagement fully mediated the association between parental health condition and children’s academic achievement and partially mediated the association between parental health condition and children’s behavior problems. Notably, higher levels of parents’ school engagement were associated with increased behavior problems, demonstrating a unique feature in these immigrant children’s developmental functioning. Higher levels of perceived harsh treatment by peers at school due to children’s immigrant identity were associated with these children’s greater risks of behavior problems. The results suggested what may lie behind the scenes in these children’s behavioral problems is that many of these children who act out and are brought to the school office for disciplinary issues may suffer from perceived discrimination and bad treatment by their peers. The findings provide important implications for researchers, healthcare practitioners, and educators seeking to understand this subpopulation and to design and implement family support and prevention programs for young adolescents from immigrant backgrounds.     

Helping Peers Seek Professional Treatment for Depression Among Young South Koreans: An Application of the Theory of Planned Behavior

This study examined the applicability of the theory of planned behavior to understand factors that influence whether young South Koreans help peers with depression to seek professional counseling services. The structural equation modeling on the survey data collected from 191 South Korean students suggests that subjective norms and behavioral control could be salient factors for young South Koreans to take initiative and assist their peers in need of counseling services. Este estudio examinó la aplicabilidad de la teoría del comportamiento planificado para comprender factores que influyen sobre la decisión de jóvenes surcoreanos de ayudar a sus compañeros que sufren de depresión a buscar ayuda profesional a través de servicios de consejería. El modelo de ecuación estructural de los datos de la encuesta recogidos de 191 estudiantes surcoreanos sugiere que las normas subjetivas y el control del comportamiento podrían ser factores destacados para los jóvenes surcoreanos a la hora de tomar la iniciativa y ayudar a sus compañeros que necesitan servicios de consejería.     

老年医学科叙事医学实践及思考

介绍老年医学科叙事医学理论学习和实践案例。应用关注、再现、反思、归属等叙事医学实践,关注老年患者主体性,发现疾病背后的故事,弥合医患视域差异,帮助老年患者及家属正视死亡教育。间接反思提升老年医学科医患沟通品质。直接反思助力医务人员发现工作中的短板,完善工作范式,提升工作品质。老年医学科叙事医学实践帮助医务人员从老年患者生命病痛的角度出发、理解和善待生命,帮助医护人员化解医患沟通困境,优化医患关系生态,全方位维护老年患者的生理、心理、情感、精神健康。

     

The Suicidal Narrative and Its Relationship to the Suicide Crisis Syndrome and Recent Suicidal Behavior

In this study, we introduce the construct of the suicidal narrative, a hypothetical personal narrative linked to imminent suicide, and explore its relationship to near‐term suicidal risk and the suicide crisis syndrome (SCS). Psychiatric outpatients (N = 289) were administered the Columbia Suicide‐Severity Rating Scale (C‐SSRS), Suicide Crisis Inventory (SCI), and Suicide Narrative Inventory (SNI), a novel instrument combining the documented risk factors of Thwarted Belongingness, Perceived Burdensomeness, Humiliation, Social Defeat, Goal Disengagement, and Goal Reengagement. Dimensional measures of past month, lifetime, and past suicidal phenomena, incorporating ideation and behavior, were calculated from the C‐SSRS. Structural equation modeling was used to explore the interaction among variables. Factor analysis of the SNI yielded two orthogonal factors, termed Interpersonal and Goal Orientation. The former factor was comprised of Perceived Burdensomeness, Social Defeat, Humiliation, and Thwarted Belongingness, the latter of Goal Disengagement and Goal Reengagement. The Interpersonal factor correlated with both SCS severity and suicidal phenomena in each time frame and the Goal Orientation factor with no other variable. As hypothesized, the proposed model was significant for the past month only. Our findings support the construct of the suicidal narrative and its function as a near‐term suicidal risk factor.     

临床医学专业人文精神教育误区探析

我国临床医学专业人文精神教育一直存在误区, 误将医学人文知识的多少等同于医学人文精神的高低;重视医学科学教育, 忽视医学人文教育;误将人文精神教育、思想政治教育、文化素质教育等同;过分夸大医学人文与医学科学的对立, 错误定义二者的关系;浮夸的技巧教育掩盖了医学人文教育的实质;传统的封闭式教学扼杀了医学人文精神教育的深入发展。只有正确认知医学人文精神教育的误区才能更好地做好医学人文精神教育, 为医学人文精神教育的发展做出贡献。