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131.
肺癌的流行始于20世纪,目前已成为全球最常见的恶性肿瘤.戒烟是已知最有效的肺癌预防策略.一百年来,全球戒烟运动的发展是曲折前行的.历史经验揭示实现肺癌的预防与控制需要一个综合、有效的戒烟运动体系,应当是多层面、多角度的.体系的构建过程将生动地见证"大医学发展观"对人类重大疾病有效控制的深刻影响. 相似文献
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Alteration of cingulate long-term plasticity and behavioral sensitization to inflammation by environmental enrichment 总被引:1,自引:0,他引:1 下载免费PDF全文
Shum FW Wu LJ Zhao MG Toyoda H Xu H Ren M Pinaud R Ko SW Lee YS Kaang BK Zhuo M 《Learning & memory (Cold Spring Harbor, N.Y.)》2007,14(4):304-312
Exposure to an enriched environment (EE) has been shown to induce cortical plasticity. Considerable amount of research is focused on the effects of EE in the hippocampus; however, effects of EE on other brain regions and the mechanisms involved are not well known. To investigate this, we induced cortical plasticity by placing mice in an EE for one month and measured the effects of EE in the anterior cingulate cortex (ACC). Here, we show that EE enhanced the expression of the plasticity gene, egr-1, in the ACC of EE animals accompanied by enhanced cingulate long-term potentiation (LTP) and decreased cingulate long-term depression (LTD). The increased NMDA receptor NR2B/NR2A subunits current ratio is associated with the plasticity seen in the ACC while total protein levels remain unchanged. Furthermore, behavioral experiments show that these mice exposed to EE demonstrate enhanced responses to acute and long-term inflammation. Our findings suggest that exposure to EE alters physiological properties within the ACC which results in enhanced responses to inflammation. 相似文献
134.
We describe our ongoing program of research related to the assessment of contextualized personality, focusing on social roles and cultural cues as contextual factors. First, we present our research employing the traditional assessment approach, wherein participants are asked to rate explicitly their personality across several different roles. We argue that this hypothetical approach is potentially susceptible to the influence of stereotypes, social desirability, and demand characteristics. We therefore describe the development of three novel and subtle assessment procedures that are based on obtaining online self-representations that are activated while occupying a specific context. Finally, the strengths and limitations of all four approaches, as well as directions for future research in the study of contextualized personality, are discussed. 相似文献
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Li Li Li‐Jung Liang Chunqing Lin Zunyou Wu Yi Wen 《International journal of psychology》2009,44(6):443-450
This study examined HIV/AIDS‐related stigma among Chinese service providers by comparing their personal attitudes toward people living with HIV/AIDS with their perception of social norms related to people living with HIV/AIDS. We randomly selected three provincial hospitals, four city/prefecture hospitals, 10 county hospitals, 18 township health clinics, and 54 village clinics from Yunnan, China. Doctors and nurses were randomly sampled proportionally to the doctor–nurse ratio of each hospital or clinic. Lab technicians were over‐sampled in order to include an adequate representation in the analysis. A total of 1,101 service providers participated in a voluntary, anonymous survey where demographic characteristics, individual attitude and perceived social norms toward people living with HIV/AIDS, discrimination intent at work, general prejudicial attitude and knowledge on HIV/AIDS were measured. A majority of the sample demonstrated a similarity between their personal views and what they thought most people in society believe. Multiple logistic regressions revealed that participants who were younger or reported personal contact with people living with HIV/AIDS were significantly more likely to report personal attitudes toward the population that were more liberal than their perceived social norms. Holding a more liberal personal attitude toward people living with HIV/AIDS than perceived social norms was significantly and negatively related to the level of discrimination intent at work, perceived discrimination at interpersonal level and the level of general prejudicial attitude toward people living with HIV/AIDS. Results underscored the importance of understanding social norms and personal attitudes in studying HIV‐related stigma and called for the incorporation of existing human capital into future HIV stigma reduction programs. 相似文献
139.
Rex E. Jung Charles Gasparovic Robert S. Chavez Arvind Caprihan Ranee Barrow Ronald A. Yeo 《Intelligence》2009,37(2):192-198
Proton magnetic resonance spectroscopy (1H-MRS) is a technique for the assay of brain neurochemistry in vivo. N-acetylaspartate (NAA), the most prominent metabolite visible within the 1H-MRS spectrum, is found primarily within neurons. The current study was designed to further elucidate NAA–cognition relationships, particularly whether such relationships are moderated by sex, or tissue type (gray or white matter). We administered standard measures of intelligence to 63 young, healthy subjects and obtained spectroscopic imaging data within a slab of tissue superior to the lateral ventricles. We found that lower NAA within right anterior gray matter predicted better performance VIQ (F = 6.83, p = .011, r2 = .10), while higher NAA within the right posterior gray matter region predicted better PIQ (F = 8.175, p = .006, r2 = .12). These findings add to the small but growing body of literature linking brain biochemistry to intelligence in normal healthy subjects using 1H-MRSI. 相似文献
140.
To assess the learning of word form and meaning in an unfamiliar writing system, we carried out primed-naming experiments with learners of Chinese at the end of their first and second terms in a Chinese class at an American university. The subjects were required to name a target Chinese character after a prime character had been presented for 500 msec. There were three priming conditions defined by the relation between the prime and the target: orthographically similar, homophonic, and semantically related. At the end of the first term, there was a significant facilitation for naming speed in the orthographic condition, but not in the homophonic or semantic conditions. However, at the end of the second term, orthographical facilitation disappeared. Instead, naming speed was facilitated by semantically related primes. A threshold-style framework was proposed to illustrate the processing of Chinese orthography, phonology, and semantics by second-language learners. 相似文献