An introduction to Bayesian hierarchical models with an application in the theory of signal detection

Although many nonlinear models of cognition have been proposed in the past 50 years, there has been little consideration of corresponding statistical techniques for their analysis. In analyses with nonlinear models, unmodeled variability from the selection of items or participants may lead to asymptotically biased estimation. This asymptotic bias, in turn, renders inference problematic. We show, for example, that a signal detection analysis of recognition memory data leads to asymptotic underestimation of sensitivity. To eliminate asymptotic bias, we advocate hierarchical models in which participant variability, item variability, and measurement error are modeled simultaneously. By accounting for multiple sources of variability, hierarchical models yield consistent and accurate estimates of participant and item effects in recognition memory. This article is written in tutorial format; we provide an introduction to Bayesian statistics, hierarchical modeling, and Markov chain Monte Carlo computational techniques.     

Internet accessibility and usage among urban adolescents in Southern California: implications for web-based health research.

The World Wide Web (WWW) poses a distinct capability to offer interventions tailored to the individual's characteristics. To fine tune the tailoring process, studies are needed to explore how Internet accessibility and usage are related to demographic, psychosocial, behavioral, and other health related characteristics. This study was based on a cross-sectional survey conducted on 2373 7th grade students of various ethnic groups in Southern California. Measures of Internet use included Internet use at school or at home, Email use, chat-room use, and Internet favoring. Logistic regressions were conducted to assess the associations between Internet uses with selected demographic, psychosocial, behavioral variables and self-reported health statuses. The proportion of students who could access the Internet at school or home was 90% and 40%, separately. Nearly all (99%) of the respondents could access the Internet either at school or at home. Higher SES and Asian ethnicity were associated with higher internet use. Among those who could access the Internet and after adjusting for the selected demographic and psychosocial variables, depression was positively related with chat-room use and using the Internet longer than 1 hour per day at home, and hostility was positively related with Internet favoring (All ORs = 1.2 for +1 STD, p < 0.05). Less parental monitoring and more unsupervised time were positively related to email use, chat-room use, and at home Internet use (ORs for +1 STD ranged from 1.2 to 2.0, all p < 0.05), but not related to at school Internet use. Substance use was positively related to email use, chat-room use, and at home Internet use (OR for "used" vs. "not used" ranged from 1.2 to 4.0, p < 0.05). Self-reported health problems were associated with higher levels of Internet use at home but lower levels of Internet use at school. More physical activity was related to more email use (OR = 1.3 for +1 STD), chat room use (OR = 1.2 for +1 STD), and at school ever Internet use (OR = 1.2 for +1 STD, all p < 0.05). Body mass index was not related to any of the Internet use-related measures. In this ethnically diverse sample of Southern California 7(th) grade students, 99% could access the Internet at school and/or at home. This suggests that the Internet is already a potential venue for large scale health communication studies. Adolescents with more psychosocial risk factors or detrimental health behaviors were more likely to use the Internet. Therefore, if used properly, Internet interventions could effectively address the high risk populations. Additional research is needed to gain a more complete understanding of the positive and negative consequences of Internet use among adolescents.     

A Web-based program for coding open-ended response protocols

A Web-based coding application was designed to improve coding efficiency and to provide a systematic means of evaluating responses to open-ended assessments. The system was developed for use by multiple raters to assign open-ended responses to predetermined categories. The application provides a software environment for efficiently supervising the work of coders and evaluating the quality of the coding by (1) systematically presenting open-ended responses to coders, (2) tracking each coder’s categorized responses, and (3) assessing interrater consistency at any time in order to identify coders in need of further training. In addition, the application can be set to automatically assign repeated responses to categories previously identified as appropriate for those responses. To evaluate the efficacy of the coding application and to determine the statistical reliability of coding open-ended data within this application, we examined data from two empirical studies. The results demonstrated substantial interrater agreement on items assigned to various categories across free and controlled association tasks. Overall, this new coding application provides a feasible method of reliably coding open-ended data and makes the task of coding these data more manageable.     

中小学生对父母管教信息的认知、情绪与行为反应倾向

运用情境模拟的方法,对中小学生对父母管教信息的认知、情绪与行为反应倾向进行了研究。被试是616名中小学生。结果表明：(1)小学中年级以上学生对家长管教信息的情绪有较准确的认知;(2)不同管教信息的教育效能有优劣之分：诱导教诲最能引起被试的正面反应,其次是困扰担忧,伤心失望能引起部分学生的顺从反应,愤怒批评易引起子女的消极情绪和对抗行为。(3)父亲发出的管教信息比母亲更具权威性,更易引起子女积极的情绪体验与行为倾向。(4)学生对家长管教信息的反应具有明显的年龄和性别差异,小学生比中学生更易接受、顺从家长管教,女生比男生易产生更多的积极情绪与服从行为。(5)被试的认知评价与其情绪反应、行为倾向有较高的一致性。学生对父母管教信息的情绪体验和行为反应很大程度上取决于对管教信息的认知。如果学生的认知较为积极,更易引起积极的情绪体验和行为倾向。     

对人眼色觉异常的定量测量研究

依据Ｒａｙｌｅｉｇｈ颜色匹配方法研制人眼颜色视觉定量测量实验装置,并对２０名色觉正常和３０名色觉异常大学生的颜色视觉进行测量。结果表明,色觉异常被试在Ｒａｙｌｅｉｇｈ匹配中点和匹配范围测量值上均与色觉正常被试者存在明显的差异。     

对当代中国新造神运动的忧与思：伪生命科学思潮批判

分析中国伪生命科学产生的文化原因和背景,指出其致命的谎言、骗术与危害;揭露其理论上的荒谬与科学上的无知。并强调开展对这类伪科学产品进行批判运动的意义;同时重新对科学、非科学、伪科学、宗教、神话、迷信等进行划界和定义。医学研究需要正义、需要哲学的引导;在事实的世界之上,必须由价值和意义的世界来把握;医学理论不允许任意杜撰和加工,从这个意义上,医学科学还需要法律来维护其正义     

现行《医疗事故处理办法》的修改探析

现行《医疗事故处理办法》颁布实施１０ 年之久,新形势下需要对其进行修改和完善。“办法”的修改应该体现平等保护医患双方合法权益原则,合理界定医疗事故范围,调整医疗事故鉴定委员会的组成,建立完善的证据管理制度,明确医疗事故损失赔偿的范围和额度。     

辩证分析兴奋性氨基酸对神经细胞的双重作用

兴奋性氨基酸（ＥＡＡｓ） 广泛分布于中枢神经系统,参与多种生理过程包括学习、记忆和伤害感受等。然而,ＥＡＡｓ 受体的过度兴奋却可引发一系列细胞事件,最终导致神经元的损伤与死亡。许多神经退行性疾病如早老性痴呆、癫痫和肌侧索硬化症等都与ＥＡＡｓ 的兴奋毒作用有关。目前的研究表明,由ＥＡＡｓ 受体过度兴奋所引发的细胞内钙超载是导致神经元死亡的最终途径     

Bidirectional semantic associations between social power and weight

Two experiments were conducted to examine bidirectional semantic associations between power and weight using a priming paradigm. Bidirectionality in the relationship between power and weight was demonstrated, utilising tasks that were identical except that the orders in which the stimuli were presented were reversed. In Experiment 1, an empty scale leaning either leftward or rightward was used as a priming stimulus, and a scale that appeared in equilibrium with a pair of power words was used as a target stimulus. In Experiment 2, a scale with a pair of words that appeared in equilibrium was used as a priming stimulus, and an empty scale leaning either leftward or rightward was used as a target stimulus. We identified interaction effects between power and weight in both experiments. Associations between power and weight provide evidence for both conceptual metaphor views and evolutionary theory. The bidirectionality of metaphorical effects is in line with the strong version of metaphoric structuring. Both language and experiential correlations play important roles in the development of the mapping between power and weight.