Exposure to severe urban air pollution influences cognitive outcomes, brain volume and systemic inflammation in clinically healthy children

Exposure to severe air pollution produces neuroinflammation and structural brain alterations in children. We tested whether patterns of brain growth, cognitive deficits and white matter hyperintensities (WMH) are associated with exposures to severe air pollution. Baseline and 1 year follow-up measurements of global and regional brain MRI volumes, cognitive abilities (Wechsler Intelligence Scale for Children-Revised, WISC-R), and serum inflammatory mediators were collected in 20 Mexico City (MC) children (10 with white matter hyperintensities, WMH⁺, and 10 without, WMH⁻) and 10 matched controls (CTL) from a low polluted city. There were significant differences in white matter volumes between CTL and MC children - both WMH⁺ and WMH⁻ - in right parietal and bilateral temporal areas. Both WMH⁻ and WMH⁺ MC children showed progressive deficits, compared to CTL children, on the WISC-R Vocabulary and Digit Span subtests. The cognitive deficits in highly exposed children match the localization of the volumetric differences detected over the 1 year follow-up, since the deficits observed are consistent with impairment of parietal and temporal lobe functions. Regardless of the presence of prefrontal WMH, Mexico City children performed more poorly across a variety of cognitive tests, compared to CTL children, thus WMH⁺ is likely only partially identifying underlying white matter pathology. Together these findings reveal that exposure to air pollution may perturb the trajectory of cerebral development and result in cognitive deficits during childhood.     

A critical review of positive education: challenges and limitations

Social Psychology of Education - Positive education has gained increased interest and attention in the last decade. Born as an applied movement within positive psychology, positive education aims...     

Estimation of the predictive power of the model in mixed‐effects meta‐regression: A simulation study

Several methods are available to estimate the total and residual amount of heterogeneity in meta‐analysis, leading to different alternatives when estimating the predictive power in mixed‐effects meta‐regression models using the formula proposed by Raudenbush (1994, 2009). In this paper, a simulation study was conducted to compare the performance of seven estimators of these parameters under various realistic scenarios in psychology and related fields. Our results suggest that the number of studies (k) exerts the most important influence on the accuracy of the results, and that precise estimates of the heterogeneity variances and the model predictive power can only be expected with at least 20 and 40 studies, respectively. Increases in the average within‐study sample size () also improved the results for all estimators. Some differences among the accuracy of the estimators were observed, especially under adverse (small k and ) conditions, while the results for the different methods tended to convergence for more optimal scenarios.     

Effects of the psycholinguistic variables on the lexical decision task in Spanish: A study with 2,765 words

In order to explore the role of the main psycholinguistic variables on visual word recognition, several mega-studies have been conducted in English in recent years. Nevertheless, because the effects of these variables depend on the regularity of the orthographic system, studies must also be done in other languages with different characteristics. The goal of this work was to conduct a lexical decision study in Spanish, a language with a shallow orthography and a high number of words. The influence of psycholinguistic variables on latencies corresponding to 2,765 words was assessed by means of linear mixed-effects modeling. The results show that some variables, such as frequency or age of acquisition, have significant effects on reaction times regardless of the type of words used. Other variables, such as orthographic neighborhood or imageability, were significant only in specific groups of words. Our results highlight the importance of taking into account the peculiarities of each spelling system in the development of reading models.     

Eating behaviors and emotional distress are predicted by treatment and adverse outcome in patients with type 2 diabetes

Depression and anxiety are hightly prevalent among patients with Type 2 Diabetes (T2D), however not commonly related to outcomes, treatment and comorbidities. Eating behaviors could also have an implication. To evaluate the relation between mood and eating behaviors with demographic, physical, treatment, biochemical profiles and chronic comorbidities in T2D we conducted this exploratory cross sectional study in a population from Mexico. Hospital Anxiety and Depression Scale and the Three Factor Eating Questionnaire Revised 21 (TFEQ-R21) were correlated with age, gender, blood pressure, treatment and comorbidities (nephropathy, neuropathy, retinopathy and cardiopathy). Multi-linear regression models and 2^k factorial analyses were conducted. Sixty-one patients (31 male) 55 years old (SD 13) with at least 5 years of T2D were included. Anxiety correlated with depression (r = 0.25, p < 0.05). Gender (women) (std B 0.026, p < 0.001), insulin therapy (std B 0.3, p = 0.11), systolic blood pressure (std B 0.263, p = 0.02) and cardiovascular disease (std B 0.232, p = 0.035) predicted depression. Insulin therapy had a positive effect in cognitive restraint. (std B 0.32, p = 0.001). Age (std B 0.37, p = 0.003) and systolic blood pressure (std B 0.237, p = 0.048) predicted positively emotional eating (not previously published). 2^k factorial analyses proved additive interaction between complications and insulin therapy with depression. This study supports the relation between mood disorders and eating behaviors with demographic, physical, treatment, biochemical profiles and chronic comorbidities in T2D and the additive interaction between factors and mood disorders.     

Validation of the Visual Analogue Scale for Anxiety-Revised and school refusal across anxiety profiles

Background/Objectives

This paper aimed to validate the Spanish version of scores of the Visual Analogue Scale for Anxiety-Revised (VAA-R) in child population, and to verify the existence of anxiety profiles and to relate them to school refusal.

Reference to Self and Other in the Digital Public Sphere: The Case of Political Blogs

In this paper, we analyze how a political blog author (Spanish Alejo Vidal-Quadras) establishes the reference to self and other in his blog entries. We furthermore look into how the commentators to this blog react and establish reference to self and other in the digital public sphere. More concretely, we show that they not only take up the references established by the main blog author but also create new references. These allow, on the one hand, for profiling themselves as part of a group and, on the other hand, identifying their interlocutor among the variety of possible interlocutors in the digital public sphere. By addressing different interlocutors, the commentators turn the comments section into a dialogic space, a dimension that is lacking in the main blog entries. However, the fact that they almost invariably identify interlocutors other than Vidal-Quadras but address Vidal-Quadras without explicitly identifying him, shows that Vidal-Quadras remains the main ratified interlocutor in view of his ownership of the blog. This paper shows then how participants in the digital public sphere create a complex relationship of self and other reference in political blogs.     

Observed actions affect body-specific associations between space and valence

Right-handers tend to associate “good” with the right side of space and “bad” with the left. This implicit association appears to arise from the way people perform actions, more or less fluently, with their right and left hands. Here we tested whether observing manual actions performed with greater or lesser fluency can affect observers' space–valence associations. In two experiments, we assigned one participant (the actor) to perform a bimanual fine motor task while another participant (the observer) watched. Actors were assigned to wear a ski glove on either the right or left hand, which made performing the actions on this side of space disfluent. In Experiment 1, observers stood behind the actors, sharing their spatial perspective. After motor training, both actors and observers tended to associate “good” with the side of the actors' free hand and “bad” with the side of the gloved hand. To determine whether observers' space–valence associations were computed from their own perspectives or the actors', in Experiment 2 we asked the observer to stand face-to-face with the actor, reversing their spatial perspectives. After motor training, both actors and observers associated “good” with the side of space where disfluent actions had occurred from their own egocentric spatial perspectives; if “good” was associated with the actor's right-hand side it was likely to be associated with the observer's left-hand side. Results show that vicarious experiences of motor fluency can shape valence judgments, and that observers spontaneously encode the locations of fluent and disfluent actions in egocentric spatial coordinates.     

Psychoanalysis of maturescence (definition,metapsychology, and clinical practice)

This article offers an entirely new way of addressing middle age or mid‐life. It uses the neologism maturescence to denote this process's metapsychological feature, and it proposes a meta‐psychology of maturescence in order to allow a ‘direct understanding of maturescence’ instead of the ‘indirect understanding of maturescence’, which psychoanalytic literature generally alludes to. The paper examines somatic processes specific to male and female climacterics and is focused on to the tension between the soma and the body. It examines the drive increase that Freud posed in climacterics and the somatic climacteric imbalance that begets specific drive activity demanding psychic work, with very different pathways depending on the individual's specific working‐through activity. It discusses what happens to the individual when he/she is no longer able to procreate and begins to age; why this process is equivalent for individuals who had children and for others who could not or did not. This somatic event provides a universal constant from which it is possible to understand any individual variable.