Atypical depression: enhanced right hemispheric dominance for perceiving emotional chimeric faces

Two studies compared hemispatial bias for perceiving chimeric faces in patients having either atypical or typical depression and healthy controls. A total of 245 patients having major depressive disorder (MDD) or dysthymia (164 with atypical features) and 115 controls were tested on the Chimeric Faces Test. Atypical depression differed from typical depression and controls in showing abnormally large right hemisphere bias. This was present in patients having either MDD or dysthymia and was not related to anxiety, physical anhedonia, or vegetative symptoms. In contrast, patients having MDD with melancholia showed essentially no right hemisphere bias. This is further evidence that atypical depression is a biologically distinct subtype and underscores the importance of this diagnostic distinction for neurophysiologic studies.     

Neighborhood predictors of hopelessness among adolescent suicide attempters: preliminary investigation

The role of neighborhood factors in predicting hopelessness among adolescent suicide attempters was examined in this study. Forty-eight adolescents who attempted suicide were administered measures of hopelessness and depression. Family socioeconomic status (SES) was calculated based on family demographics and characteristics of neighborhood context were examined using a geocoding software package. Adolescents who lived in neighborhoods with weak social networks reported higher levels of hopelessness, even after controlling for SES and depression. These preliminary findings suggest that environmental context may play a role in the emotional status of adolescents who attempt suicide.     

A contribution of cognitive decision models to clinical assessment: decomposing performance on the Bechara gambling task

The Bechara simulated gambling task is a popular method of examining decision-making deficits exhibited by people with brain damage, psychopathology, antisocial personality, or drug abuse problems. However, performance on this task is confounded by complex interdependencies between cognitive, motivational, and response processes, making it difficult to sort out and identify the specific processes responsible for the observed behavioral deficits. The authors compare 3 competing cognitive decision models of the Bechara task in terms of their ability to explain the performance deficits observed in Huntington's disease patients as compared with healthy populations and people with Parkinson's disease. The parameters of the best fitting model are used to decompose the observed performance deficit of the Huntington patients into cognitive, motivational, and response sources.     

A crossmodal attentional blink between vision and touch

There is currently a great deal of interest regarding the possible existence of a crossmodal attentional blink (AB) between audition and vision. The majority of evidence now suggests that no such crossmodal deficit exists unless a task switch is introduced. We report two experiments designed to investigate the existence of a crossmodal AB between vision and touch. Two masked targets were presented successively at variable interstimulus intervals. Participants had to respond either to both targets (experimental condition) or to just the second target (control condition). In Experiment 1, the order of target modality was blocked, and an AB was demonstrated when visual targets preceded tactile targets, but not when tactile targets preceded visual targets. In Experiment 2, target modality was mixed randomly, and a significant crossmodal AB was demonstrated in both directions between vision and touch. The contrast between our visuotactile results and those of previous audiovisual studies is discussed, as are the implications for current theories of the AB.     

Immunity to functional fixedness in young children

In thecandle problem (Duncker, 1945), subjects must attach a candle to a vertical surface, using only a box of tacks and a book of matches. Subjects exhibitfunctional fixedness by failing, or being slow, to make use of one object (the tack box) as a support, rather than as a container, in their solutions. This failure to produce alternate functions is measured against improved performance when the tack box is presented empty rather than full of tacks (i.e., not preutilized as a container). Using an analogous task, we show that functional fixedness can be demonstrated in older children (6- and 7-year-olds); they are significantly slower to use a box as a support when its containment function has been demonstrated than when it has not. However, younger children (5-year-olds) are immune to this effect, showing no advantage when the standard function is not demonstrated. Moreover, their performance under conditions of preutilization is better than that of both older groups. These results are interpreted in terms of children’s developing intuitions about function and the effects of past experience on problem solving.     

医学与文学的传统及创新

论述医学与文学关系的文章习惯以阿波罗开头。文学与医学直到最近才成为医学人文学里的一个新的学术分支 ,但文学与医学的关系至少可追溯到古希腊。本文中 ,我将讨论如何看待医学与文学关系的四种传统方式 :其一 ,疾病的形象 (ｉｍａｇｅｓ) ,即文学中患病、苦难和死亡的主题 ;其二 ,治疗者的形象 ;其三 ,医生—诗人或医生—作家类型 ;其四 ,文学作为一种治疗方法。然后 ,我将简要讨论文学在今日医学教育中的作用并提供一个思辨性的结论。1　传统1 1　患病、苦难和死亡的主题与医学一样 ,文学关涉患病、苦难和死亡这些与人类同样古老的主题…     

Establishing derived requesting skills in adults with severe developmental disabilities

This project examined whether a history of reinforced relational responding would result in derived requesting skills in 3 adults with disabilities. Participants were first taught to request preferred items using pictures; they were then taught conditional discriminations between pictures and their dictated names and between dictated names and their corresponding text. Finally, requests for preferred items using corresponding text were evaluated. All 3 participants demonstrated derived requesting skills.     

A case study of mediated learning, delayed auditory feedback, and motor repatterning to reduce stuttering

A case study of DW, an 11-yr. old monolingual, English-speaking boy who exhibits stuttering, language delay, and ADHD is presented. DW experienced only limited improvement during stuttering therapy received in public schools, according to parents and the public school clinician. The purpose of this case study was to assess whether fluency treatment which incorporated Mediated Learning, Delayed Auditory Feedback, and Speech Motor Repatterning would enhance progress. Therapy was delivered in two treatments, with each treatment being 5 wk. of intense therapy, separated by one year. Treatment 1 of combined Mediated Learning and Delayed Auditory Feedback yielded improvement in fluency, judged by parents and the teacher to be clinically significant. The improved fluency was maintained for one year when DW was pretested for participation in Treatment 2, which combined Mediated Learning, Delayed Auditory Feedback, and Speech Motor Repatterning Exercises. As no conclusions are possible, further study is needed.