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571.
People with Williams syndrome are characterized by linguistic abilities that are higher than their level of intelligence. There is controversy concerning their reading level because there are few studies. The aim of this work was to test reading abilities in a group of school-age children with Williams syndrome. Their performance was contrasted with a control group of the same mental age. Three kinds of tasks were used: word and pseudoword reading, phonological awareness, and naming speed. Results show that the Williams syndrome children performed similarly to control children in reading accuracy but were slower in reading words and pseudowords. They were also slower in the naming speed tasks. These results suggest that Williams syndrome children do not have difficulties in developing grapheme-phoneme decoding but do present some difficulties in developing lexical reading. 相似文献
572.
Structure of personality pathology in normal and clinical samples: Spanish validation of the DAPP-BQ 总被引:1,自引:0,他引:1
Gutiérrez-Zotes JA Gutiérrez F Valero J Gallego E Baillés E Torres X Labad A Livesley WJ 《Journal of personality disorders》2008,22(4):389-404
Given that the DSM taxonomy of personality disorders is flawed by severe classificatory problems, the development of alternative classificatory systems, such as the Dimensional Assessment of Personality Pathology-Basic Questionnaire (DAPP-BQ), has now become a priority. This study examined the internal consistency, second-order factor structure, and criterion validity of a Spanish translation of the DAPP-BQ in two samples: subjects with personality disorder (n = 155) and subjects from the general population (n = 300). Alpha coefficients ranged satisfactorily from .75 to .93. Four second-order factors of Emotional Dysregulation, Dissocial Behavior, Inhibitedness, and Compulsivity were obtained, which were replicable between samples and identical to those reported in the literature. Finally, disordered subjects scored significantly higher than normal subjects on 17 of the 18 DAPP-BQ traits. Some pending issues in the construction of an alternative taxonomy of personality disorders are discussed. 相似文献
573.
Epp J Keith JR Spanswick SC Stone JC Prusky GT Sutherland RJ 《Learning & memory (Cold Spring Harbor, N.Y.)》2008,15(4):214-221
It is generally believed that the hippocampus is not required for simple discrimination learning. However, a small number of studies have shown that hippocampus damage impairs retention of a previously learned visual discrimination task. We propose that, although simple discrimination learning may proceed in the absence of the hippocampus, it plays an important role in this type of learning when it is intact. In order to test the role of the hippocampus in simple discrimination learning, we performed a series of experiments utilizing a two-choice picture discrimination task. Our experiments confirm that rats readily learn simple two-choice picture discriminations after hippocampus damage. However, if such discriminations are first learned while the hippocampus is intact, subsequent hippocampus damage causes severe retrograde amnesia for the discriminations. Furthermore, retrograde amnesia for simple picture discriminations was equally severe when the interval between training and damage was 1 d or 60 d; remote picture memories are not spared. Similarly, the rule or schema underlying a recently or remotely acquired picture discrimination learning set was lost after hippocampus damage. The severity of retrograde amnesia for simple picture discriminations is negatively correlated with the volume of spared hippocampus tissue. Thus, the hippocampus plays an essential role in long-term memories supporting simple picture discriminations. 相似文献
574.
Christopher Gyngell Thomas Douglas Julian Savulescu 《Journal of applied philosophy》2017,34(4):498-513
Germline Gene Editing (GGE) has enormous potential both as a research tool and a therapeutic intervention. While other types of gene editing are relatively uncontroversial, GGE has been strongly resisted. In this article, we analyse the ethical arguments for and against pursuing GGE by allowing and funding its development. We argue there is a strong case for pursuing GGE for the prevention of disease. We then examine objections that have been raised against pursuing GGE and argue that these fail. We conclude that the moral case in favour of pursuing GGE is stronger than the case against. This suggests that pursuing GGE is morally permissible and indeed morally desirable. 相似文献
575.
Fernando Rudy‐Hiller 《Pacific Philosophical Quarterly》2017,98(Z1):398-426
Ignorance usually excuses from responsibility, unless the person is culpable for the ignorance itself. Since a lot of wrongdoing occurs in ignorance, the question of what makes ignorance culpable is central for a theory of moral responsibility. In this article I examine a prominent answer, which I call the ‘volitionalist tracing account,’ and criticize it on the grounds that it relies on an overly restrictive conception of responsibility‐relevant control. I then propose an alternative, which I call the ‘capacitarian conception of control,’ and on the basis of it I advance an account of culpable ignorance that avoids the skeptical upshots of the volitionalist proposal. If correct, my account establishes three important truths: agents can be directly in control of their ignorance, they can be directly responsible for more than actions and omissions, and their moral obligations extend beyond the performance of intentional actions and omissions. 相似文献
576.
This study examines the concept of engagement in samples of volunteers from different non‐profit organisations. Study 1 analyzes the psychometric properties of the abbreviated version of the Utrecht Work Engagement Scale (UWES) ( Schaufeli, Bakker, & Salanova, 2006a ). Two factorial structures are examined: one‐dimensional and three‐dimensional structures. Based on the Three‐Stage Model of Volunteers' Duration of Service ( Chacón, Vecina, & Dávila, 2007 ), Study 2 investigates the relationship between engagement, volunteer satisfaction, and intention to remain in a sample of new volunteers and the relationship between engagement, organisational commitment, and intention to remain in a sample of veteran volunteers. Moderated mediation analysis is provided using duration of service as a moderator in order to set a splitting point between new and veteran volunteers. The results of the confirmatory factor analysis suggest that the three‐factor model fits better to the data. Regarding the structural models, the first one shows that engagement is crucial to volunteer satisfaction during the first stage, while volunteer satisfaction is the key variable in explaining intention to continue. The second structural model shows that engagement reinforces the participant's commitment to the organisation, while organisational commitment predicts intention to continue. Both models demonstrate a notable decline when samples are changed. 相似文献
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