Academic Guidance in Medical Student Research: How Well Do Supervisors and Students Understand the Ethics of Human Research?

Research is increasingly recognised as a key component of medical curricula, offering a range of benefits including development of skills in evidence-based medicine. The literature indicates that experienced academic supervision or mentoring is important in any research activity and positively influences research output. The aim of this project was to investigate the human research ethics experiences and knowledge of three groups: medical students, and university academic staff and clinicians eligible to supervise medical student research projects; at two Australian universities. Training in research ethics was low amongst academic staff and clinicians eligible to supervise medical student research. Only two-thirds of academic staff (67.9 %) and students (65.7 %) and less than half of clinicians surveyed (47.1 %; p?=?0.014) indicated that specific patient consent was required for a doctor to include patient medical records within a research publication. There was limited awareness of requirements for participant information and consent forms amongst all groups. In the case of clinical trials, fewer clinicians (88.4 %) and students (83.3 %) than academics (100 %) indicated there was a requirement to obtain consent (p?=?0.009). Awareness of the ethics committee focus on respect was low across all groups. This project has identified significant gaps in human research ethics understanding among medical students, and university academic staff and clinicians. The incorporation of research within medical curricula provides the impetus for medical schools and their institutions to ensure that academic staff and clinicians who are eligible and qualified to supervise students’ research projects are appropriately trained in human research ethics.     

Stressors and Stress Reactions Among University Personnel

A large, ethnically diverse, and representative sample of university workers in administrative, instructional, and blue-collar/clerical support categories were administered a battery of questionnaires designed to assess job and nonwork stress, biopsychosocial reactions to stress, emotionality, medical symptoms and utilization, and perceived social support, among other variables. A total of 831 participants returned questionnaires. The principal results showed that job and nonwork stress correlated positively with behavioral, cognitive, and physiological reactions to stress as well as with negative emotionality. Job and nonwork stress correlated meaningfully with medical symptoms; nonwork stress also correlated at a useful level with reported medical utilization. Social support did not generally modulate reports of stress or reactions to stress. It was also found that support staff reported higher levels of nonwork stress and lower levels of work stress, but that 2 measures of job stress did not differentiate administrative and instructional personnel. Younger staff reported higher levels of job and nonwork stress, and females reported higher levels of nonwork stress, irrespective of job category. The results were discussed in terms of their importance for understanding the nature of stress among personnel on the university campus and in relation to prior research.     

On the stability of the arousal strength of warning signal words

Studies are reported that demonstrate the stability of scales of the arousal strength of warning signal words. We demonstrate that these scales are not an artefact of the measurement technique employed, nor are they influenced by the effects of experimental context. In addition, we generalize previous findings on the arousal strength of signal words to the UK population. Separate studies revealed a high level of agreement in signal word arousal strengths derived from magnitude estimation, category estimation, and cross‐modality matching. In addition, the relative arousal strengths of signal words were shown to be independent of the composition of the warning stimulus set. These findings suggest that arousal strength scales of signal words are robust and that signal words can be used with confidence to achieve hazard matching between the hazard inherent in a product/situation and the hazard implied by the associated warning. Copyright © 2000 John Wiley & Sons, Ltd.     

Religiosity and Attitudes Toward Diversity: A Potential Workplace Conflict?1

The study investigates relationships between 2 measures of religiosity (immanence orientation and religious fundamentalism) and 2 measures of attitudes toward diversity (universal‐diverse orientation and attitudes toward gay men and lesbians). As expected, different conceptualizations of religiosity relate differently to diversity attitudes. Immanence orientation related positively and religious fundamentalism related negatively with both measures of diversity attitudes. However, when both measures were included in the hierarchical regression equation, immanence orientation no longer related significantly with attitudes toward lesbians and gay men; and religious fundamentalism no longer related significantly with universal‐diverse orientation. Finally, gender and immanence interacted to predict universal‐diverse orientation. Implications are discussed.     

Predictors of Cancer Worry in Unaffected Women from High Risk Breast Cancer Families: Risk Perception is not the Primary Issue

Some women at increased familial risk of breast cancer experience elevated levels of cancer-specific worry, which can possibly act as a barrier to screening, and may be a significant factor in decisions regarding risk-reducing surgery. The aim of this study was to comprehensively examine predictors of cancer-specific worry in high risk women and to test a model which proposes that perceived breast cancer risk mediates the impact of other factors on worry. 1,437 unaffected women from high risk breast cancer families completed questionnaires and interviews. Path analysis was used to test the model of potential predictors of cancer worry, including familial, personal and psychological variables, mediated via perceived cancer risk. Levels of cancer-specific worry were generally low despite an average perceived risk of 50.3%. The goodness-of-fit of the proposed model was poor, explaining only 9% of the variance for perceived risk and 10% of the variance for cancer specific worry. An alternative model of a direct relationship between all of the predictor variables and cancer worry, explained 24% of the variation in cancer worry. General anxiety, perceived risk, the stressful impact of recent cancer related events, a relative risk greater than 10, being closer in age to the youngest breast cancer diagnosis in family, and knowledge of personal mutation status, all independently contributed to cancer worry. Addressing general affective responses, experiences of recent cancer related events, in addition to education about personal risk, should be considered in counselling women with elevated cancer worry. Risk perception appears to act independently of other factors in its formulation and impact on cancer worry. Further research on the way in which women come to perceive their risk is indicated. The kConFab Psychosocial Group are (in alphabetical order of institution): Brain and Mind Institute, University of Sydney, Australia (I Hickie) Department of Haematology and Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, Australia (K-A Phillips) Department of Medical Oncology, Prince of Wales Hospital, Randwick, Australia (B Bennett, B Meiser, K Tucker) Department of Oncology, St Vincent’s Hospital, Melbourne, Australia (S-A MaLachlan) Department of Psychological Medicine, Royal North Shore Hospital, St Leonards, Australia (C Tennant); Medical Psychology Research Unit, University of Sydney, Australia (P Butow, M Price).     

Progressive age-related changes in the attentional blink paradigm

Previous studies on aging and attention typically examine group differences between younger and older adults, rather than seeing aging as a continuous process. Using correlational analyses, this study examined progressive changes in the magnitude of the attentional blink (AB) associated with aging. Increased age was found to be significantly associated with the ability to detect the second target (T2), whereby older age was correlated with the production of a longer and more pronounced AB; this supports the proposition that aging is associated with reduced inhibitory processes and selective attention. It was also found that AB performance somewhat improves between ages 18-39 years, but tends to decline from 40 years of age onward, providing an interesting and novel finding that AB effects may become more sensitive at this point in time. The AB task may prove useful in the assessment of selective attention in normal healthy adults, as well as changes associated with pathological aging.     

Effects of perceived criticism on anxiety and depression during behavioral treatment of anxiety disorders

The present study explored the effect of perceived criticism (PC) on levels of anxiety and depression during behavioral treatment among patients diagnosed with obsessive-compulsive disorder (OCD) or panic disorder with agoraphobia (PDA). We posited that patients' perceptions of relatives' criticism and the degree to which they were upset by the criticism (UC) would be related to negative affect and discomfort during exposure. The sample included 75 patients with a primary diagnosis of OCD (n=43) or PDA (n=32) and their participating relatives. Measures of patients' weekly ratings of PC and upset about the criticism, anxious and depressed mood, and subjective discomfort during exposure treatment were analyzed using a mixed model regression approach (SAS Proc Mixed). Patients' anxious and depressed mood predicted greater discomfort during exposure. Patients who were more UC also had higher weekly ratings of anxiety and depression, and more discomfort during exposure sessions. Findings suggest that treatment outcome may be improved by attention to patients' reactions to their interpersonal environment.     

Acoustic,semantic and phonetic influences in spoken warning signal words

Three experiments are reported which explore the relationship between semantic, acoustic and phonetic variables in the judgement of eight warning signal words. Experiment 1 shows that listeners can distinguish very clearly between urgent and non‐urgent versions of the words when spoken by real speakers, and that some signal words such as ‘deadly’ and ‘danger’ score more highly than words such as ‘attention’ and ‘don't’. It also shows that the three dimensions of perceived urgency, appropriateness and believability of these words are highly correlated. Experiment 2 replicates Experiment 1 using synthesized voices where acoustic variables are controlled. The semantic effects are replicated, and to some extent appropriateness and believability are found to function differently from that of perceived urgency. Experiment 3 compares the same set of eight signal words with a set of phonetically similar neutral words, showing that warning signal words are rated significantly higher, and largely maintain their previous rank ordering. Copyright © 2003 John Wiley & Sons, Ltd.     

Connotative Interpretations of Sexuality-Related Terms

In this study we examined the connotative interpretations of selected sexuality-related terms by a cohort of university undergraduate students (n=567). Forty-two sexuality-relevant constructs were rated on thirty 7-point semantic differential scales. Means of the scale sum scores for men and women were compared using t tests. Among women the most favorably rated constructs were orgasm, vaginal sex, sexual intercourse, virginity, masturbation, oral sex, pro-choice, pregnancy, erection, and heterosexual. The most negatively evaluated terms were date rape, sexual abuse, rape, sexual assault, HPV, and HIV/AIDS. For men, the most favorably rated constructs were sexual monogamy, virginity, orgasm, vaginal sex, and heterosexual. The most negatively evaluated terms were rape, HPV, date rape, and sexual abuse. There were statistically significant gender differences in the evaluation of 12 terms (p<.05). The evaluations assigned to 30 possible attributes suggest that some sexuality-related terms elicit strong visceral responses from university students. A discussion of the psychological and emotional impact of sexuality-related terms (i.e., connotative meanings) may be warranted whenever dictionary definitions (i.e., denotative meanings) are presented to students, other groups of learners, and persons in health care and other settings. Moreover, a practitioner's use of language may elicit connotatively different responses for women and men.