Male Swiss mice were allowed to explore a novel environment, provided by an open-field activity chamber, for 10 min. The procedure was repeated twice with a 24-h interval. The difference in the exploratory activity between the first (training) and the second (testing) exposures to the chamber was taken as an index of retention of this habituation task. Posttraining intraperitoneal administration of glucose (10–300 mg/kg) enhanced retention in a dose-related manner, although only the dose of 30 mg/kg of glucose produced significant effects. Thus, the dose–response curve adopted an inverted U-shaped form. Glucose (30 mg/kg) given to untrained mice did not modify their exploratory performance when recorded 24 h later. The effects of glucose on retention were time-dependent, suggesting an action on memory storage. The memory-improving actions of glucose were prevented by the simultaneous administration of both the central acting muscarinic cholinergic antagonist atropine (0.5 mg/kg) and by the central acting nicotinic cholinergic antagonist mecamylamine (5 mg/kg). In contrast, neither methylatropine (0.5 mg/kg), a peripherally acting muscarinic receptor blocker, nor hexamethonium (5 mg/kg), a peripherally acting nicotinic receptor blocker, prevented the effects of glucose on retention. Low subeffective doses of glucose (10 mg/kg) and the central anticholinesterase physostigmine (35 μg/kg), but not neostigmine (35 μg/kg), given together, act synergistically and facilitated retention. We suggest that glucose modulates memory storage of one form of learning elicited by stimuli repeatedly presented without reinforcement, probably through an enhancement of brain acetylcholine synthesis and/or its release. 相似文献
Garcia, J. The Logic and Limits of Mental Aptitude Testing. American Psychologist, 1981, 36, 1172–1180. Hargadon, F. Tests and College Admissions. American Psychologist, 1981, 36, 1112–1119. 相似文献
Summary Pigeons learned to discriminate a large number of bilateral symmetric and asymmetric visual patterns successively projected on the pecking-key of an operant conditioning chamber. Responses to the positive stimuli were reinforced according to a variable interval schedule. Once acquisition was complete generalization trials, involving sets of new stimuli, were instituted under extinction. The birds classified these novel test stimuli with high accuracy throughout, according to their symmetry or asymmetry. Their performance was not disturbed by sets of test stimuli whose geometrical style differed considerably from the training stimuli. Pigeons were even able to discriminate when only allowed the use of one eye. The generalization series were partly designed to test some classical symmetry recognition theories. None was found to be adequate. Subsidiary experiments suggested that most pigeons have a slight spontaneous preference for asymmetric patterns and that symmetry/asymmetry differences can aid pattern discrimination learning at an early stage. It is concluded that pigeons, much like humans, can discriminate bilaterally symmetric from non-symmetric visual forms in a concept-like, generalizing way. The ontogenetic and phylogenetic development of this competence is considered. A novel symmetry recognition hypothesis based on spatial frequency analysis and neuronal feature-detector considerations is proposed. 相似文献
Summary The aim of this work is the demonstration of a tactile-kinesthetic aftereffect. A sequence of stimuli was offered to adult subjects whose task was to compare two weights presented simultaneously to both hands by means of a Piéron gravimeter. In Experiment 1 the inspection stimuli consisted of two successive presentations of unequal weights for a period of 2 × 10 s. The test stimuli consisted of two equal weights rapidly following an inspection stimulus. Control stimuli consisting of two equal weights not preceded by an inspection stimulus were interspersed in the sequence. The results obtained confirm the existence of a contrast effect after presentation of an inspection stimulus. In Experiment 2 the inspection stimuli consisted of a single presentation of two unequal weights for a period of 20 s. The results confirm those of the first experiment and provide data enabling the contrast effect obtained to be interpreted as a Köhler-type aftereffect. In order to avoid confusion with the kinesthetic-figural aftereffect, we propose to call the effect demonstrated here the Gravimetric Aftereffect. 相似文献
Integrated primary and behavioral health care (IPBH) is becoming a preferred mode of service delivery in the United States. Integrated care includes the participation of medical and mental health professionals, such as mental health counselors. The clinical outcomes of these professionals need to be studied to determine their effectiveness in such settings. We examined the performance of 10 mental health counselors on the clinical outcome of 1,747 clients treated in an IPBH center. Analyses using growth curve modeling and pre‐post test design revealed that mental health counselors were effective overall, but they differed in client dropout rates and efficiency in reducing clients' initial symptoms. We used the analyses to rank order counselors based on their effectiveness. Counselors who were the most effective varied in their efficiency but demonstrated the lowest client dropout rates. Implications for future research and counseling practice were discussed. 相似文献
This study explored the influence of each family member’s life satisfaction on the other family members’ life satisfaction in mother-father-adolescent triads. We also explored the influence of each family member’s satisfaction with food-related life and family life on their own life satisfaction (LS) as well as on the other family members’ LS in mother-father-adolescent triads. The influence of family eating habits, food-related parenting practices used by each parent and sociodemographic characteristics on each family member’s LS were also explored. A survey was applied to a sample of 300 two-parent families with one child between 10 and 17 years of age in Temuco, Chile. The questionnaire included the Satisfaction with Life Scale, Satisfaction with Food-related Life scale, Satisfaction with Family Life scale, Adapted Healthy Eating Index, Family Food Behavior Survey and Family Eating Habits Questionnaire. Frequency and sources of family meals as well as sociodemographic characteristics were also consulted. Three multivariate ordinal logit models were proposed, with the dependent variable LS in the three subsamples: mothers, fathers and adolescents. The three logit models were significant, but differed in the explanatory variables. Mothers’ LS was influenced by their children’s LS and vice versa. Mothers’ LS was positively influenced by both their own satisfaction with family life and the fathers’ satisfaction with family life and vice versa. Children’s LS was also positively influenced by their own satisfaction with food-related and family life. Both parents’ LS was influenced by eating habits, food-related parenting practices and sociodemographic characteristics, but in different ways. Therefore, different interventions should be implemented to improve each family member’s life satisfaction.
Cognitive Processing - Mandarin speakers, similar to speakers of most other languages around the world, tend to conceptualize time in terms of space. However, it has been supposed that Mandarin... 相似文献