Gamma-hydroxybutyrate (GHB) is a drug with significant abuse potential. The present study aimed to assess the relative value of escalating doses of GHB to current GHB users via the Multiple Choice Procedure (MCP), and to validate that the dose rated highest with the MCP would be self-administered at a greater rate than placebo. Participants were 5 current GHB users who were not currently trying to stop using GHB. To examine the value of escalating doses of GHB, the following doses of GHB were used: 0 (placebo), 12.5, 25, 37.5, and 50 mg/kg. Participants typically assigned higher doses of GHB had higher crossover points on the MCP. During choice sessions, participants made repeated choices between administering GHB, placebo or nothing. All participants selected GHB exclusively (5 out of 5 instances) except for one participant who selected GHB on 4 out of 5 instances, thus 96% (i.e., 24/25) of choices were for active GHB. Based on these data, GHB appears likely to function as a dose-dependent reinforcer for humans based on our sample. 相似文献
The trajectory toward tenure is complex and arduous, and it requires one to balance attention among diverse and competing
demands. It is not surprising that many newly appointed assistant professors report struggling with this process. Borrowing
from family and ecological systems theories, we proffer a framework that may help junior faculty members—defined in this article
as tenure-earning assistant professors—learn about the tenure-earning process as they navigate through the university system
and beyond. We also describe and clarify the many parts of the tenure-earning process, including the roles, responsibilities,
and multiple contexts that must be considered concurrently by junior faculty members as they progress through the stages of
their tenure-earning appointment in the academy. 相似文献
The Therapists'Information About Women Scale (TIWS) and Therapists'Attitude Toward Women Scale (TAWS) are presented. Results from a sample of 184 therapists (social workers, psychiatrists, and psychologists) showed no significant differences among professions; however, women therapists were significantly better informed, more liberal, and less stereotyped in their attitudes. Information and attitudes were correlated.57. Though attitudes were more liberal than stereotyped, many therapists showed a lack of pertinent information and attitudes likely to conflict with those of their women patients. 相似文献
In order to investigate whether addressees can make immediate use of speaker-based constraints during reference resolution, participant addressees’ eye movements were monitored as they helped a confederate cook follow a recipe. Objects were located in the helper’s area, which the cook could not reach, and the cook’s area, which both could reach. Critical referring expressions matched one object (helper’s area) or two objects (helper’s and cook’s areas), and were produced when the cook’s hands were empty or full, which defined the cook’s reaching ability constraints. Helper’s first and total fixations showed that they restricted their domain of interpretation to their own objects when the cook’s hands were empty, and widened it to include the cook’s objects only when the cook’s hands were full. These results demonstrate that addressees can quickly take into account task-relevant constraints to restrict their referential domain to referents that are plausible given the speaker’s goals and constraints. 相似文献
Because of the benefits of group-counseling experiences, the lack of psychological services for older adults, and the unique concerns of aged women, a group-counseling program for aged women was conducted. The results of these efforts are presented for the purposes of sharing the proposed program sequence, describing what actually took place during the group sessions, conveying the comments and reactions offered by the group participants, and summarizing what we learned about facilitating groups for aged women. 相似文献
AbstractPre-school children find it difficult to correctly report if it is morning or afternoon. The present study tested whether children could learn a non-verbal Time-Place Learning (TPL) task that depended on time of day. Twenty-five 4-year-olds were repeatedly asked to find a toy in one of two boxes. Children in the Cued condition were told the toy was in one box in the morning and in another box in the afternoon. Children in the Not Cued condition were told the toy was sometimes in one box and sometimes in the other box. After 80 trials, children were asked if it was morning or afternoon. About 65% of the children learned the TPL task, and about three-quarters of the children verbally identified if it was morning or afternoon. However, the children who learned the TPL task were not necessarily the children who correctly answered whether it was morning or afternoon, and those in the Cued condition were no more likely to solve the task than those in the Not Cued condition. The implication is that children have a sense of time that can be used to solve spatio-temporal contingencies, but does not depend on the verbal understanding of time of day. 相似文献
Theories of visual attention hypothesize that target selection depends upon matching visual inputs to a memory representation of the target – i.e., the target or attentional template. Most theories assume that the template contains a veridical copy of target features, but recent studies suggest that target representations may shift "off veridical" from actual target features to increase target-to-distractor distinctiveness. However, these studies have been limited to simple visual features (e.g., orientation, color), which leaves open the question of whether similar principles apply to complex stimuli, such as a face depicting an emotion, the perception of which is known to be shaped by conceptual knowledge. In three studies, we find confirmatory evidence for the hypothesis that attention modulates the representation of an emotional face to increase target-to-distractor distinctiveness. This occurs over-and-above strong pre-existing conceptual and perceptual biases in the representation of individual faces. The results are consistent with the view that visual search accuracy is determined by the representational distance between the target template in memory and distractor information in the environment, not the veridical target and distractor features.