Proportionate responses to life events influence clinicians' judgments of psychological abnormality

Psychological abnormality is a fundamental concept in the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR; American Psychiatric Association, 2000) and in all clinical evaluations. How do practicing clinical psychologists use the context of life events to judge the abnormality of a person's current behaviors? The appropriate role of life-event context in assessment has long been the subject of intense debate and scrutiny among clinical theorists, yet relatively little is known about clinicians' own judgments in practice. The authors propose a proportionate-response hypothesis, such that judgments of abnormality are influenced by whether the behaviors are a disproportionate response to past events, rendering them difficult to understand or explain. Licensed, practicing clinical psychologists (N = 77) were presented with vignettes describing hypothetical people's behaviors (disordered, mildly distressed, or unaffected) that had been preceded by either traumatic or mildly distressing events. Experts' judgments of abnormality were strongly and systematically influenced by the degree of mismatch between the past event and current behaviors in strength and valence, such that the greater the mismatch, the more abnormal the person seemed. A separate, additional group of clinical psychologists (N = 20) further confirmed that the greater the degree of mismatch, the greater the perceived difficulty in understanding the patient. These findings held true across clinicians of different theoretical orientations and in disorders for which these patterns of judgments ran contrary to formal recommendations in the DSM-IV-TR (American Psychiatric Association, 2000). The rationality of these effects and implications for clinical decision science are discussed.     

Diagnostic Exome Sequencing Identifies Two Novel IQSEC2 Mutations Associated with X-Linked Intellectual Disability with Seizures: Implications for Genetic Counseling and Clinical Diagnosis

Intellectual disability is a heterogeneous disorder with a wide phenotypic spectrum. Over 1,700 OMIM genes have been associated with this condition, many of which reside on the X-chromosome. The IQSEC2 gene is located on chromosome Xp11.22 and is known to play a significant role in the maintenance and homeostasis of the brain. Mutations in IQSEC2 have been historically associated with nonsyndromic X-linked intellectual disability. Case reports of affected probands show phenotypic overlap with conditions associated with pathogenic MECP2, FOXG1, CDKL5, and MEF2C gene mutations. Affected individuals, however, have also been identified as presenting with additional clinical features including seizures, autistic-behavior, psychiatric problems, and delayed language skills. To our knowledge, only 5 deleterious mutations and 2 intragenic duplications have been previously reported in IQSEC2. Here we report two novel IQSEC2 de novo truncating mutations identified through diagnostic exome sequencing in two severely affected unrelated male probands manifesting developmental delay, seizures, hypotonia, plagiocephaly, and abnormal MRI findings. Overall, diagnostic exome sequencing established a molecular diagnosis for two patients in whom traditional testing methods were uninformative while expanding on the mutational and phenotypic spectrum. In addition, our data suggests that IQSEC2 may be more common than previously appreciated, accounting for approximately 9 % (2/22) of positive findings among patients with seizures referred for diagnostic exome sequencing. Further, these data supports recently published data suggesting that IQSEC2 plays a more significant role in the development of X-linked intellectual disability with seizures than previously anticipated.     

Re-examining Religiosity as a Protective Factor: Comparing Alcohol Use by Self-Identified Religious,Spiritual, and Secular College Students

Religiosity has been found to be associated with lower alcohol use by college students. The majority of studies on this topic, however, fail to differentiate religiosity and spirituality. This is potentially problematic due to the changing face of religion in America today. A study was conducted to explore similarities and differences between self-identified religious and spiritual college students. A modified version of the Core Alcohol and Drug Survey was administered online with a sample of 2,312 students. As hypothesized, self-identified religious and spiritual students differed significantly on key variables related to religious practices, alcohol consumption, and postmodern social values.     

A Description–Experience Gap in Social Interactions: Information about Interdependence and Its Effects on Cooperation

In social interactions, decision makers are often unaware of their interdependence with others, precluding the realization of shared long‐term benefits. In an experiment, pairs of participants played an Iterated Prisoner's Dilemma under various conditions involving differing levels of interdependence information. Each pair was assigned to one of four conditions: “No‐Info” players saw their own actions and outcomes, but were not told that they interacted with another person; “Min‐Info” players knew they interacted with another person but still without seeing the other's actions or outcomes; “Mid‐Info” players discovered the other's actions and outcomes as they were revealed over time; and “Max‐Info” players were also shown a complete payoff matrix mapping actions to outcomes from the outset and throughout the game. With higher levels of interdependence information, we found increased individual cooperation and mutual cooperation, driven by increased reciprocating cooperation (in response to a counterpart's cooperation). Furthermore, joint performance and satisfaction were higher for pairs with more information. We discuss how awareness of interdependence may encourage cooperative behavior in real‐world interactions. Copyright © 2013 John Wiley & Sons, Ltd.     

Testing a longitudinal social cognitive model of intended persistence with engineering students across gender and race/ethnicity

We examined the temporal relations within Lent et al.'s (2013) integrative SCCT model of academic satisfaction and intended persistence in a sample of 551 engineering undergraduates from a Hispanic serving institution. They completed measures of instrumentality, support, self-efficacy, outcome expectations, interests, academic satisfaction, and intended persistence at two time points approximately 12 months apart. Using longitudinal cross-panel design, the findings supported a model where: (a) instrumentality predicted self-efficacy, (b) self-efficacy was a temporal precursor for both interests and academic satisfaction, (c) support was a temporal precursor for outcome expectations, while also predicting academic satisfaction, (d) academic satisfaction and intended persistence had a reciprocal relation with one another, and (e) relations in the model did not differ by gender or race/ethnicity. Implications for future research and practice are discussed.     

Reducing the Linear Perception of Nonlinearity: Use of a Physical Representation

Research shows that while judging accumulations of quantities over time (e.g., money in a bank account or CO₂ in Earth's atmosphere), people assume that the shape of the accumulation is similar to the shape of the inflow (i.e., people rely on a correlation heuristic). Relying on the correlation heuristic is particularly worrisome for Earth's climate, as judging the CO₂ accumulation according to its emissions (inflow) would underestimate the actual (nonlinear) increase. This misperception undermines the seriousness of climate problem and results in wait‐and‐see behavior. We report two experiments where the effectiveness of a physical representation is compared with graphical and text representations in reducing people's underestimation of nonlinear accumulation in different contexts and problems. A physical representation presents an accumulation using a picture that works as a metaphor. In the first experiment, participants drew the shape of an accumulation over time relying on physical or graphical representations in one of two contexts: carbon dioxide and marbles. Although the participants underestimated the accumulation in both contexts, underestimations were reduced in the physical representation compared with the graphical representation. In the second experiment, we extended the evaluation of physical representations against both text and graphical representations in two different climate problems (with linearly increasing or decreasing inflow). Again, underestimations of the accumulation were reduced in the physical representation compared with the other two representations, regardless of the nature of the problem. We discuss implications of using the physical representation for improving people's estimates of nonlinear CO₂ accumulation. Copyright © 2011 John Wiley & Sons, Ltd.     

Cultural dimensions,socioeconomic development,climate, and emotional hedonic level

A research synthesis was conducted with four studies which correlated national mean self-ratings of affect balance (positive minus negative affect) and subjective well-being with the nations' cultural characteristics (individualism, masculinity, uncertainty avoidance, and power-distance national scores on Hofstede's dimensions), socioeconomic development (Human Development Index), and climate (absolute latitude). A meta-analysis of these collective level cross-cultural studies shows that individualism correlates positively with affect balance and subjective well-being, controlling for socioeconomic development, cultural femininity, power-distance, uncertainty avoidance, and climate. Similar results were found for individual-level data. The meaning of collective-level or national means of individual self-reports of affect balance is discussed.     

Testing parameters in structural equation modeling: every "one" matters

A problem with standard errors estimated by many structural equation modeling programs is described. In such programs, a parameter's standard error is sensitive to how the model is identified (i.e., how scale is set). Alternative but equivalent ways to identify a model may yield different standard errors, and hence different Z tests for a parameter, even though the identifications produce the same overall model fit. This lack of invariance due to model identification creates the possibility that different analysts may reach different conclusions about a parameter's significance level even though they test equivalent models on the same data. The authors suggest that parameters be tested for statistical significance through the likelihood ratio test, which is invariant to the identification choice.     

Estimation of speakers' weight and height from speech: a re-analysis of data from multiple studies by Lass and colleagues

Research on identification of speakers' weight and height from their speech has yielded controversial results. Conclusions from a series of reports conducted by Lass and colleagues must be interpreted with caution because they are based on comparisons of only two types of data, mean of actual values and mean of estimated values. Cohen and others clearly demonstrated that this method of analysis overstated the accuracy of listeners' judgments. Following Van Dommelen's procedure, data from six of Lass's reports were re-analyzed with more appropriate statistics. Results of re-analysis show that (a) listeners are not very efficient guessing the weight or height of speakers, as only 14%, of the estimations correlated significantly with actual values. (b) Judgments are highly consistent under different acoustic conditions, suggesting that listeners follow vocal stereotypes about the body size of speakers, even though these stereotypes are wrong.