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The current study used the partially-baited radial-arm maze paradigm to study the effects of a single-treatment high-dose exposure ('binge') to MDMA (± 3,4-methylenedioxymethaphemtamine or 'Ecstasy') on memory task acquisition. Sprague-Dawley rats were administered a binge dose (4 × 10 mg/kg) of MDMA and their ability to subsequently acquire the radial-arm maze task was compared against saline controls. The MDMA-treated rats were significantly slower to learn the task and made more reference memory errors than the controls. Working memory function was found to be relatively unimpaired. Following a reversal of task rules the MDMA-treated rats were again significantly slower to acquire the appropriate rule despite having eventually achieved a similar level of overall performance as control rats. However evidence of drug tolerance was found when all rats were challenged with an acute low dose of MDMA (1 × 4.0 mg/kg) because the binge MDMA rats were relatively less impaired. Therefore, although binge treated MDMA rats were able to achieve very accurate performance equivalent to the controls they took significantly longer to do this and were less able to adapt their behavior to a change in task rules. In addition the binge treated MDMA rats displayed tolerance to acute MDMA exposure. These findings are consistent with the possibility that human Ecstasy users may show deficits in acquiring information and may experience deficits in cognitive flexibility as well as developing tolerance to the drug with repeated exposure.  相似文献   
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Despite growing recognition that systemic family therapists need to be adept at personal reflection and managing the therapeutic relationship, little research has explored the effects of training beyond the development of skills. This article provides a report on a qualitative study focussed on the personal effects of family therapy training, with particular reference to the aspects of training that foster personal reflection and growth. Twenty three trainees from three training institutions were interviewed, utilizing the practices of grounded theory. Trainees reported a deepening relational awareness, which applied to both personal and professional domains and included shifts in perspectives on relationships with loved ones. Five aspects of training were identified as responsible: (1) personally challenging experiences with clients; (2) supervisors who live the paradigm; (3) the demystification of theory; (4) a safe supervisory space; and (5) the development of trusting peer relationships. Interns also described, in turn, how their personal development affected their clinical work, particularly in the development of compassion and empathy. This study serves to highlight training practices that support reflective practice in systemic family therapy.  相似文献   
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In many tasks people have to coordinate the information from several sources. An example would be driving a car while listening to directions. The driver has to establish a correspondence between a visual picture and verbal instructions. This paper addresses two questions concerning information coordination. Is there an ability to coordinate information received from several sources that is different from the ability to deal with information from each source, alone? Does coordination simply involve allocating resources to deal with the component tasks, or does the act of coordination itself constitute a separate task? Four experiments examined the coordination of a verbal component task with a visual-spatial and with an auditory component task. The results showed that the ability to coordinate perceptual and verbal information is separate from the ability to deal with either perceptual or verbal information, alone. A simple resource sharing model was not adequate in explaining how coordination occurred. We relate our results to a model in which perceptual reasoning occurs independently of verbal processing, but transforming perceptual information into a propositional form is affected by concurrent verbal processing.  相似文献   
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Over the last several years, researchers have become increasingly interested in the influence of moral factors on bullying behaviors. This is the first meta-analytic review to exclusively examine the relationship between moral disengagement (MD) and the key bullying roles of bully, victim, defender, and bystander. Forty-seven independent samples examining a total of 43,809 children/adolescents (aged 7–19) were included in this meta-analysis. Results indicated a positive relationship between MD and bullying (r = 0.31; 95% CI [0.27, 0.34]), MD and victimization (r = 0.08; 95% CI [0.05, 0.12]), and a negative relationship between MD and defending (r = −0.11; 95% CI [−0.17, −0.04]). No significant relationship was found for MD and bystanding behavior. Moderators of bullying type (traditional vs. cyberbullying), reporting type (self vs. peer report), age, and gender were included in the analyses. The results are discussed in the context of relevant literature with particular emphasis on the importance of distinguishing between guilty and unconcerned bystanders, and the significant overlap between bullying and victimization in the cyber context.  相似文献   
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Identifying causal relationships is an important aspect of research and evaluation in visitor studies, such as making claims about the learning outcomes of a program or exhibit. Experimental and quasi-experimental approaches are powerful tools for addressing these causal questions. However, these designs are arguably underused in visitor studies. In this article, we offer examples of the use of experimental and quasi-experimental designs in science museums to aide investigators interested in expanding their methods toolkit and increasing their ability to make strong causal claims about programmatic experiences or relationships among variables. Using three designs from recent research (fully randomized experiment, posttest only quasi-experimental design with comparison condition, and posttest with independent pretest design), we discuss challenges and tradeoffs related to feasibility, participant experience, alignment with research questions, and internal and external validity. We end the article with broader reflections on the role of experimental and quasi-experimental designs in visitor studies.  相似文献   
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Converging evidence supports a distributed-plus-hub view of semantic processing, in which there are distributed modular semantic sub-systems (e.g., for shape, colour, and action) connected to an amodal semantic hub. Furthermore, object semantic processing of colour and shape, and lexical reading and identification, are processed mainly along the ventral stream, while action semantic processing occurs mainly along the dorsal stream. In Experiment 1, participants read a prime word that required imagining either the object or action referent, and then named a lexical word target. In Experiments 2 and 3, participants performed a lexical decision task (LDT) with the same targets as in Experiment 1, in the presence of foils that were legal nonwords (NW; Experiment 2) or pseudohomophones (PH; Experiment 3). Semantic priming was similar in effect size regardless of prime type for naming, but was greater for object primes than action primes for the LDT with PH foils, suggesting a shared-stream advantage when the task demands focus on orthographic lexical processing. These experiments extend the distributed-plus-hub model, and provide a novel paradigm for further research.  相似文献   
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