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941.
Studzinski CM Christie LA Araujo JA Burnham WM Head E Cotman CW Milgram NW 《Neurobiology of learning and memory》2006,86(2):197-204
Visuospatial learning and memory impairments are an early marker for age-related cognitive decline and Alzheimer's disease. Similar to humans, aged dogs show visuospatial learning and memory deficits (). One hundred and nine beagle dogs ranging between 0.25 and 11.99 years were tested on a visuospatial delayed non-matching to position (DNMP) task to better characterize the progression of visuospatial deficits in the dog. Age predicted 48.2% of the variability in learning the DNMP, with dogs ranging from 1 to 11.99 years generally making more errors with increasing age. By contrast, puppies (<1 year) likely were showing developmental deficits, possibly due to an immature prefrontal cortex. Mild visuospatial deficits were detected by 6 years, which precedes the typical onset of amyloid-beta (Abeta) accumulation in the dog brain by two years, and can serve as an early marker for cognitive decline in the dog. These findings suggest that (1) age-related changes in visuospatial function in the dog models that seen in humans, further validating the dog as a model for human aging and dementia; and (2) other mechanisms, such as oxidative stress, soluble Abeta oligomers or cholinergic deficits, are likely contributing to the early impairment. 相似文献
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944.
Structural equation modeling (SEM) can be adapted in a relatively straightforward fashion to analyze data from interchangeable dyads (i.e., dyads in which the 2 members cannot be differentiated). The authors describe a general strategy for SEM model estimation, comparison, and fit assessment that can be used with either dyad-level or pairwise (double-entered) dyadic data. They present applications illustrating this approach with the actor-partner interdependence model, confirmatory factor analysis, and latent growth curve analysis. 相似文献
945.
Poor socioeconomic status and African American (AA) ethnicity contribute to an increased risk of obesity for many inner city children. One hundred and forty six AA children and 108 AA parents attending an inner city health fair completed surveys regarding perceptions of their own (or their child's) weight and the impact of weight on health. The children were measured and their body mass indexes were calculated. Thirty-seven percent of the child respondents (n = 52) were at risk of overweight or overweight; of these, 67% perceived themselves as normal weight, and 77% thought their weight was healthy. Weighing more was felt to be healthy by 17% of children and 29% of parents. Of 39 parents whose children were at risk of overweight or overweight, 68% felt their child's weight was normal and 80% thought it was healthy. These results suggest that inner city AA children and their parents often do not recognize being overweight or the health implications of being overweight. 相似文献
946.
The relation of adolescents' experiencing parental divorce, their perception of parents' characteristics, and their perception of the ideal mate's characteristics was investigated. One hundred adolescents from intact families and 79 from nonintact families were asked to rank both the degree to which each of 40 personality traits characterized their parents and the degree to which each characterized an ideal partner. The results indicated that there was no significant difference between adolescents from intact and nonintact families in the independence of their characterizations of their ideal mate and of their parents. However, differences were found on some of the personality dimensions that were investigated. These and other findings are discussed within the framework of psychoanalytic theory. 相似文献
947.
This study evaluated the efficacy of behavioral and cognitive-behavioral one-session exposure treatment procedures with and without programmed generalization for participants with small animal phobias. Forty participants were randomly assigned to the treatment and generalization conditions. Both treatments produced significant improvements from pre-test to post-test and these results were maintained for 1 year. The treatment effect sizes ranged from large to very large across behavioral, self-report, and subjectively rated measures. Participants in the behavioral treatment condition reported that the treatment was significantly more intrusive than participants in the cognitive-behavioral treatment group. The programmed generalization condition did not produce additional measured benefit. The results are discussed in terms of the overall effectiveness of one-session exposure treatment components for small animal phobias. 相似文献
948.
Regulatory fit and persuasion: transfer from "Feeling Right." 总被引:3,自引:0,他引:3
The authors propose that when a message recipient "feels right" from regulatory fit (E. T. Higgins, 2000), this subjective experience transfers to the persuasion context and serves as information for relevant evaluations, including perceived message persuasiveness and opinions of the topic. Fit was induced either by strategic framing of message arguments in a way that fit/did not fit with the recipient's regulatory state or by a source unrelated to the message itself. Across 4 studies, regulatory fit enhanced perceived persuasiveness and opinion ratings. These effects were eliminated when the correct source of feeling right was made salient before message exposure, supporting the misattribution account. These effects reversed when message-related thoughts were negative, supporting the claim that fit provides information about the "rightness" of one's (positive or negative) evaluations. 相似文献
949.
Nolan JE 《Perceptual and motor skills》2004,99(1):63-82
The effects of perceptual motor training in children with learning disabilities have been hotly debated for many years. Proponents have included many of the pioneers in the fields of learning disabilities and motor development. Among the challenges perhaps the most sophisticated one has been the meta-analysis by Kavale and Mattson. Their conclusion was that perceptual motor training was not an effective intervention for children with disabilities. The purpose of this project was to analyze critically the Kavale and Mattson meta-analysis from the perspective of an adapted physical educator and to consider the validity of this meta-analysis when examining multiple interventions dealing with a multitude of disabilities. A critical analysis of all 180 studies question their conclusions. 相似文献
950.
Describing memory for a nonverbal perceptual stimulus can impair recognition. This verbal overshadowing effect may occur when perceptual expertise exceeds verbal expertise, but previous evidence for this hypothesis has been strictly correlational. We conducted two experiments, exploring the relation between expertise and verbal overshadowing by manipulating perceptual and conceptual knowledge. Participants received perceptual training (categorizing mushrooms), conceptual training (lecture), or no training, then viewed a mushroom and described it or not. A recognition test followed. In Experiment 1, perceptual training increased susceptibility to verbalization relative to the no training condition. However, conceptual training did not insulate individuals from the verbal overshadowing effect. Experiment 2 was modified to enhance both forms of training. It replicated the finding that perceptual training increases vulnerability to verbal overshadowing, and indicated that, when sufficiently emphasized, verbalization may be useful following conceptual training. The results demonstrate the role that different forms of learning and expertise may play in mediating language influences on recognition memory. 相似文献