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81.
NMDA and muscarinic receptors of the nucleus accumbens have differential effects on taste memory formation 下载免费PDF全文
Ramírez-Lugo L Zavala-Vega S Bermúdez-Rattoni F 《Learning & memory (Cold Spring Harbor, N.Y.)》2006,13(1):45-51
Animals recognize a taste cue as aversive when it has been associated with post-ingestive malaise; this associative learning is known as conditioned taste aversion (CTA). When an animal consumes a new taste and no negative consequences follow, it becomes recognized as a safe signal, leading to an increase in its consumption in subsequent presentations (attenuation of neophobia, AN). It has been shown that the nucleus accumbens (NAcc) has an important role in taste learning. To elucidate the involvement of N-methyl-D-aspartate (NMDA) and muscarinic receptors in the NAcc during safe and aversive taste memory formation, we administrated bilateral infusions of DL-2-amino-5-phosphonopentanoic acid (APV) or scopolamine in the NAcc shell or core respectively. Our results showed that pre-training injections of APV in the NAcc core and shell disrupted aversive but not safe taste memory formation, whereas pre-training injections of scopolamine in the NAcc shell, but not core, disrupted both CTA and AN. These results suggest that muscarinic receptors seem to be necessary for processing taste stimuli for either safe or aversive taste memory, whereas NMDA receptors are only involved in the aversive taste memory trace formation. 相似文献
82.
The aim of this study was to investigate the role of discrete emotions in lexical processing and memory, focusing on disgust and fear. We compared neutral words to disgust-related words and fear-related words in three experiments. In Experiments 1 and 2, participants performed a lexical decision task (LDT), and in Experiment 3 an affective categorisation task. These tasks were followed by an unexpected memory task. The results of the LDT experiments showed slower reaction times for both types of negative words with respect to neutral words, plus a higher percentage of errors, this being more consistent for fear-related words (Experiments 1 and 2) than for disgust-related words (Experiment 2). Furthermore, only disgusting words exhibited a higher recall accuracy than neutral words in the memory task. Moreover, the advantage in memory for disgusting words disappeared when participants carried out an affective categorisation task during encoding (Experiment 3), suggesting that the superiority in memory for disgusting words observed in Experiments 1 and 2 could be due to greater elaborative processing. Taken together, these findings point to the relevance of discrete emotions in explaining the effects of the emotional content on lexical processing and memory. 相似文献
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84.
Chelsey M. Hartley Jeremy W. Pettit Daniel M. Bagner José R. Rosa-Olivares 《Journal of psychopathology and behavioral assessment》2018,40(3):402-411
The purpose of the current study was to develop and evaluate a measure of maternal reward responsivity in parenting. Deficits in reward responsivity, a common feature of depression, may contribute to maladaptive parenting behaviors. Reward responsivity is an individual difference in reactivity to pleasurable stimuli and represents a key motivational component that could contribute to the frequency and quality of mothers’ interactions with their infants. However, there is currently no measure of reward responsivity in parenting, which would be necessary to evaluate the link between mother reward responsivity, behaviors towards their infant, and infant behavior. Therefore, the current study reports on the development and initial evaluation of a self-report measure of reward responsivity in parenting, the Mother Inventory of Reward Experience (MIRE). We evaluated the MIRE among 200 mothers (M?=?28.45, SD?=?5.50) recruited from a pediatric primary care center. After item analysis, 22 items were retained and displayed high internal consistency reliability and test re-test reliability. Convergent validity was established via a significant correlation with global reward responsivity. Concurrent validity was established via significant correlations with depressive symptoms, parenting stress, and child behavior problems. Incremental validity of the MIRE over a measure of global reward responsivity was supported. These results support the reliability and validity of the MIRE as a measure of reward responsivity in parenting. 相似文献
85.
José Ángel Gascón 《Argumentation》2018,32(2):155-173
Virtuous arguers are expected to manifest virtues such as intellectual humility and open-mindedness, but from such traits the quality of arguments does not immediately follow. However, it also seems implausible that a virtuous arguer can systematically put forward bad arguments. How could virtue argumentation theory combine both insights? The solution, I argue, lies in an analogy with virtue epistemology: considering both responsibilist and reliabilist virtues gives us a fuller picture of the virtuous arguer. 相似文献
86.
This longitudinal study was conducted among 102 women with non-metastasic breast cancer to identify the time evolution and prevalence of distress at specific times through diagnosis and treatment of disease: preliminary diagnosis, surgery, definitive diagnosis and chemotherapy. Additionally, the study aimed to examine the role of demographic, medical and psychosocial factors on distress. The results indicated that prevalence of distress was higher at initial diagnosis (25%) than the following time points (approximately 17%). The differences inter-individuals in the levels of distress were observed over the four assessments. No relation between distress and demographic and medical factors was found. However, psychosocial aspects were significant risk factors. Patterns of emotional suppression and specific coping responses like helplessness/hopelessness, anxious preoccupation, cognitive avoidance and fatalism were positively related to distress, whereas fighting spirit and perceived social support showed a protective role. Moreover, helplessness/hopelessness and anxious preoccupation jointly predicted 75% of cases and 98% non-cases of distress. Finally, a mediational model between emotional suppression and distress through helplessness/hopelessness was tested. Results support the necessity of routine distress screening all through the illness. Implications of data for psychosocial interventions with breast cancer patients are highlighted. 相似文献
87.
Do political preferences reflect individual differences in interpersonal orientations? Are conservatives less other‐regarding than liberals? On the basis of past theorising, we hypothesised that, relative to individuals with prosocial orientations, those with individualistic and competitive orientations should be more likely to endorse conservative political preferences and vote for conservative parties. This hypothesis was supported in three independent studies conducted in Italy (Studies 1 and 2) and the Netherlands (Study 3). Consistent with hypotheses, a cross‐sectional study revealed that individualists and competitors endorsed stronger conservative political preferences than did prosocials; moreover, this effect was independent of the association between need for structure and conservative political preferences (Study 1). The predicted association of social value orientation and voting was observed in both a four‐week (Study 2) and an eight‐month (Study 3) longitudinal study. Taken together, the findings provide novel support for the claim that interpersonal orientations, as measured with experimental games rooted in game theory, are important to understanding differences in ideology at the societal level. Copyright © 2011 John Wiley & Sons, Ltd. 相似文献
88.
Examining the validity of the family investment and stress models and relationship to children's school readiness across five cultural groups 总被引:2,自引:0,他引:2
Using the Early Childhood Longitudinal Study, Birth Cohort (ECLS-B) dataset, this study examined whether the family investment and the family stress models generalized to non-European American (EA) families. Specifically, we examined whether parenting processes mediated the association between family demographics and children's school readiness, and whether the pathways vary across cultural groups. Both models were most salient for EAs followed by African Americans (AAs) and Spanish-speaking Hispanics, but less so for English-speaking Hispanics (EHs) and Asian Americans. Findings indicated that sensitive parenting was a salient mediator between family demographics and children's school readiness for all groups except EHs; negative parenting and parent-child activities were salient mediators for EAs only. 相似文献
89.
Araújo Lima AM Cordeiro Hirata Fde C Sales de Bruin G Salani Mota RM Bruin VM 《Behavioural neurology》2012,25(2):119-125
The aim of this study is to evaluate the acute effect of playing games on executive function and motor ability in Parkinson's disease (PD). Consecutive cases with PD were studied with the Unified Parkinson Disease Rating Scale (UPDRS), Mini-Mental State examination (MMSE), Beck Depression Inventory (BDI), Stroop test, finger tapping and 14-meter walk test. After randomization, patients performed a game of dominoes and were tested before and after experiment being further categorized as control, winners or non-winners. Forty patients, 27 male (67.5%), aged 48 to 84 years (63.2 ± 8.5), Hoehn & Yahr I to III were included. Twenty-eight (70%) presented depressive symptoms (BDI > 10). Groups (Control N = 13; Winners = 14 and Non-winners = 13) were not different regarding age, disease duration, age at onset, BMI, MMSE scores, depressive symptoms, levodopa dose, and previous practice of games. Winners presented significantly better results on executive function (Stroop test, p = 0.002) and on motor activity (Finger tapping, p = 0.01). Non-winners showed a trend of better performance in the 14-meter-walk test. This study shows that the practice of a non-reward game acutely improved memory and motor skills in PD. Our results suggest a role for the reward system in the modulation of the dopaminergic function of the basal ganglia in these patients. 相似文献
90.
This study investigated the role of adolescents' cognitive ability, personality traits and school success in predicting later criminal behaviour. Cognitive ability, the five‐factor model personality traits and the school grades of a large sample of Estonian schoolboys (N = 1919) were measured between 2001 and 2005. In 2009, judicial databases were searched to identify participants who had been convicted of misdemeanours or criminal offences. Consistent with previous findings, having a judicial record was associated with lower cognitive ability, grade point average, agreeableness, and conscientiousness and higher neuroticism. In multivariate path models, however, the contributions of cognitive ability and conscientiousness were accounted for by school grades and the effect of neuroticism was also accounted for by other variables, leaving grade point average and agreeableness the only independent predictors of judicial record status. Copyright © 2011 John Wiley & Sons, Ltd. 相似文献