Communication of Information about Genetic Risks: Putting Families at the Center

Genetic information is a family affair. With the expansion of genomic technologies, many new causal genes and variants have been established and the potential for molecular diagnoses increased, with implications not only for patients but also their relatives. The need for genetic counseling and intrafamilial circulation of information on genetic risks grew accordingly. Also, the amount and, particularly, the complexity of the information to convey multiplied. Sharing information about genetic risks with family members, however, has never been an easy matter and often becomes a source of personal and familial conflicts and distress. Ethical requisites generally prevent healthcare professionals from directly contacting their consultands' relatives (affected or still at risk), who often feel unsupported throughout that process. We discuss here the communication of genetic risks to family members. We first consider genomic testing as a basis for family‐centered health care, as opposed to a predominant focus on the individual. We reviewed the literature on sharing genetic risk information with family members, and the associated ethical issues for professionals. Some clinical cases are presented and discussed, and key issues for meeting the needs of individuals and families are addressed. We argue that genetic information is inextricably linked to the family and that communicating about genetic risks is a process grounded within the broader milieu of family relationships and functioning. We conclude for the need for a more family‐centered approach and interventions that can promote sensitive attitudes to the provision of genetic information to and within the family, as well as its inclusion in educational and training programmes for genetic healthcare professionals.     

Effects of the dialectical behavioral therapy-mindfulness module on attention in patients with borderline personality disorder

It is known that patients with borderline personality disorder (BPD) show attention deficits and impulsivity. The main aim of this study was to explore the effects of Dialectical Behavioral Therapy-Mindfulness training (DBT-M), used as an adjunct to general psychiatric management (GPM), on attention variables in patients diagnosed with BPD. A second objective was to assess the relation of mindfulness formal practice on clinical variables. A sample of 60 patients with BPD was recruited. Forty of them were allocated to GPM + DBT-M treatment and the other 20 received GPM alone. At the termination of the mindfulness training, DBT-M + GPM group showed a significant improvement on commissions, hit reaction time, detectability scores from the CPT-II neuropsychological test, and also on the composite scores of inattention and impulsivity. Further, the more minutes of mindfulness practice were correlated to greater improvement in general psychiatric symptoms and affective symptomatology, but not in CPT-II measures. This is probably the first study so far assessing the effects of this single DBT module in patients with BPD. The results suggest a positive effect of such intervention on attention and impulsivity variables.     

Predator-elicited foot shakes in wall lizards (Podarcis muralis): evidence for a pursuit-deterrent function

Under certain circumstances, prey may inform potential predators of their unprofitability by means of pursuit-deterrent signals. The evidence for pursuit-deterrent signaling in reptiles is scant and taxonomically biased. Wall lizards, Podarcis muralis (Squamata: Lacertidae) produce several distinct types of stereotyped foot shake displays, of which one, performed in antipredator contexts, is a likely candidate for a pursuit-deterrent function. We investigated this possibility by recording the responses of lizards in the field to a slowly approaching human acting as a surrogate predator. In addition to starting and flight initiation distances, we measured the presence of foot shakes, the leg that was shaken, and the distance from the observer at which the display was performed (display distance). Of a total of 484 approaches, 109 (22.5%) elicited foot shake displays. Roughly half the lizards displayed from the location where they were first sighted, while the other half moved a short distance, then displayed. There was no left-right preference in the leg used to display, but most lizards displayed with the leg closer to the approaching predator. Juveniles and subadults had smaller flight initiation distances than adult lizards. There were no sex-related differences in starting or flight initiation distances, but females, for a given distance, were more likely to display than males. Foot shake display frequency declined abruptly at 1 m. If lizards waited until the surrogate predator was this close, they mostly fled without displaying. Our results show that antipredator foot shaking in P. muralis is consistent with expectations from pursuit-deterrent theory.     

Modulator effect of socio-emotional variables on training in elaboration strategies in Compulsory Secondary Education (CSE): paraphrase and applications

The purpose of this work is to verify the modulation of motivation, self-concept, and causal attributions in the efficacy of a training program of strategies to elaborate information in the stage of Compulsory Secondary Education (CSE). We selected 328 students from CSE, 179 from second grade and 149 from fourth grade, and three measurement moments: pretest, posttest, and follow-up. The results indicate greater use of learning strategies by students with higher intrinsic motivation, in contrast to students with higher extrinsic motivation, who use learning strategies less frequently. With regard to self-concept, the results differ as a function of the course. In second grade, we found modulation of the variable Academic self-concept, whereas in fourth grade, such modulation is produced by General self-concept and Private self-concept. In general, there is a tendency towards more enduring significant improvements in students with medium and high self-concept, especially in their perception of the use of strategies or in complex tasks that involve relating the contents to be learned with experiences from their daily life. However, students with low self-concept significantly improve strategies associated with learning how to perform specific tasks.     

Role of TRPV1 in consolidation of fear memories depends on the averseness of the conditioning procedure

Despite the fact that TRPV1 receptors are widely expressed in brain structures such as the hippocampus, its functions remain largely unknown. In the present study, we have investigated the possible modulatory role of the hippocampal endovanilloid system upon memory consolidation of two different behavioral tasks in rats. Post-training infusion of the TRPV1 antagonist capsazepine disrupted memory consolidation with a strong training protocol, but not with a weak one in the contextual fear conditioning or in the step-down inhibitory avoidance task. These results provide evidence that the modulation of the hippocampal memory consolidation through TRPV1 receptors takes place only in presence of a strong emotional experience, suggesting that a certain aversiveness level is required in order to recruit endovanilloids to exert this function. A possible synergic role of hippocampal endovanilloid and endocannabinoid system on memory consolidation is discussed.     

Homing in rocky intertidal fish. Are Lipophrys pholis L. able to perform true navigation?

Although navigation is common in many animals, only a few perform true navigation, meaning that they have the ability to return to a given place by relying on indirect cues obtained at the release site (i.e., by relying on information from a “map and compass” mechanism). The common intertidal fish, Lipophrys pholis, is thought to have homing abilities through a mechanism that primarily makes use of familiar landmarks (i.e., piloting). Anecdotal reports that individuals return to their home pools after release at unfamiliar sites suggest that L. pholis might use cues collected at the release site to find their way back (i.e., they might use map and compass information). Using a completely artificial setup, we tested the homing abilities of L. pholis as a function of age, sex, and familiarity with the release site. The findings showed that motivation for homing is present only in the adult phase and is independent of sex and/or familiarity with the release site. Moreover, adults released at a completely unfamiliar place oriented themselves in a direction roughly similar to that of their home pools. The fact that L. pholis were tested in a complete artificial environment means that hydrodynamic cues can be excluded as playing a role in this process and restricts the candidate options (e.g., magnetic cues). The ability to perform navigation based on a “map and compass” mechanism raises many interesting questions about the learning process, once these individuals have restricted home ranges during their lives. In vertebrate navigation, the cues used during the navigation process are a question of debate, and L. pholis offers an outstanding model to test hypotheses and ultimately provide answers.     

Sobre los orígenes de la psicología científica en España: El papel del movimiento krausista

Resumen

Parece incuestionable que una de las principales líneas de penetración de la psicología científica en España se realiza a través de la influencia del krausismo positivo. El presente artículo intenta analizar y comprender este fenómeno. En primer lugar, se expone la situación científica y filosófica española en el momento en que la psicología europea adquiere con Wundt el carácter de disciplina independiente: la precaria situación de la ciencia experimental en España pone en manos de los filósofos (especialmente los vinculados a la tradición krausista) la tarea de incorporar los resultados de la nueva ciencia psicológica. En segundo lugar, se destacan algunas de las principales aportaciones psicológicas de ese pensamiento krausopositivista. Y, finalmente, como explicación de este hecho, se pone de relieve la centralidad que la temática psicológica tenía ya en el pensamiento krausista anterior; es, por tanto, la fidelidad a los propios principios de este pensamiento lo que impulsa a un diálogo con la psicología europea del momento, según las directrices que ésta marcaba.     

Estrategias de decisión de un jurado bajo condiciones de simulación

Resumen

El objeto de esta investigación es analizar el proceso de decisión de un jurado bajo condiciones de simulación. A través de dos experimentos en que se manipula la forma de presentación de la información, se estudian los efectos de la regla de decisión y de las instrucciones en el veredicto y los efectos de la deliberación. Se defiende la hipótesis de que la regla de decisión y las instrucciones tienen respectivamente efectos informativos y normativos sobre el veredicto, y que la deliberación tiene efectos informativos. Estos efectos, sin embargo, sólo resultan parcialmente evidentes en el contexto de una estrategia de juicio compensatoria que supone el procesamiento analítico de la evidencia aportada en el juicio. Los resultados muestran que los sujetos cambian de estrategia cuando cambia la forma de presentación y el tipo de respuesta solicitada que es holística, de elección y no compensatoria en la presentación simultánea y analítica, de juicio y compensatoria en la presentación secuencial. Sólo cuando la deliberación supone un cambio de estrategia tiene un efecto sobre el veredicto que es más favorable que lo que lo era inicialmente para el acusado. Los resultados parecen adecuarse a un modelo de acumulación de evidencia que afecta a la evaluación de los ítems incriminatorios del caso.     

Psycholinguistic variables involved in concept recall from the successive presentation of features / Variables psicolingüísticas involucradas en la evocación de conceptos a partir de la presentación de atributos sucesivos

Abstract

The aim of this study was to analyse the psycholinguistic variables of the attributes and concepts involved in the recall of a concept. One hundred and twenty adults (18–40 years old) participated. A lexical recall task was administered by presenting a successive list of defining attributes. Forty concepts from different semantic categories were used. The attributes were obtained empirically from local Semantic Features Production Norms. The influence of the characteristics and attributes of the concepts on the number of participants who accessed the name of the concept and the correct guess trend was analysed. Significant values for Age of Acquisition, Presence of Distinctive Attributes and Presence of Taxonomic Attributes were observed. Results show that concepts which are acquired earliest are more easily recalled; presenting taxonomic categories narrows the search and the presence of distinctive attributes allow differentiating between such concepts within a category.     

The Necessary Limits to Temptation: The Turnkey Project

In case of special engineering projects of important relevance it is interesting to pay attention to several possible risks; some of them are in the field of morality or ethics. Due to the social importance of these risks, additional considerations or even additional warranties are justified.