Updating the contents of working memory in depression: interference from irrelevant negative material

This study was designed to assess the effects of irrelevant emotional material on the ability to update the contents of working memory in depression. For each trial, participants were required to memorize 2 lists of emotional words and subsequently to ignore 1 of the lists. The impact of irrelevant emotional material on the ability to update the contents of working memory was indexed by response latencies on a recognition task in which the participants decided whether or not a probe was a member of the relevant list. The authors compared response latencies to probes from the irrelevant list to response latencies to novel probes of the same valence (intrusion effect). The results indicate that, compared to control participants in both neutral and sad mood states, depressed participants showed greater intrusion effects when presented with negative words. In an important finding, intrusion effects for negative words were correlated with self-reported rumination. These findings indicate that depression is associated with difficulties removing irrelevant negative material from working memory. Results also indicate that the increased interference from irrelevant negative material is associated with rumination.     

The number of active palmar sweat glands (palmar sweat index,PSI) as an activation measure in field studies

The number of active sweat glands within a defined area of a fingertip, called the palmar sweat index (PSI), can be easily determined by means of the plastic fingerprint method. Two experiments were carried out to demonstrate the applicability of this technique in field research and to investigate the properties of the PSI as an activation parameter. In Experiment 1 (in a blood donors’ ward), PSI rose significantly during venous puncture and dropped after the cannula had been installed. In Experiment 2 (in a dental office), PSI values increased when patients were seated in the dental chair and rose to a higher level at the dentist’s entry. Values after treatment were significantly lower. In both experiments, it was observed that the initial assessments yielded higher PSI values. This is best explained as a reaction to the assessment procedure itself, and it is recommended that the first two prints not be used for the determination of baseline values.     

Coincidence of attention deficit disorder and atopic disorders in children: Empirical findings and hypothetical background

ADDH children are often reported to display signs of allergies to various substances and/or atopic (AT) symptoms (i.e., atopic eczema, hay fever, or asthma). Since, at least for a subgroup of these children, a common biological background for both ADD and atopy may be assumed that may involve brain catecholamines, our hypothesis was that in a group of AT children (mainly atopic eczema) signs of ADD should appear more often than in controls. Parental hyperactivity ratings revealed a significantly higher frequency of ADD symptoms in the AT group, and laboratory tests sensitive to attentional capacity and inhibitory functions showed poorer performance in the AT children, the findings being similar to those reported in hyperactives. Thus, our results add support to the assumption of a common predisposing factor for both AT and ADDH in a subgroup of children.     

Gravitational lensing and Hacking's extragalactic irreality

In Extragalactic Reality: The Case of Gravitational Lensing Hacking resumes the discussion of scientific realism from the last chapter of Representing and Intervening. Since the criterion of manipulability cannot be applied to astronomical objects, experimental entity realism seems to be restricted to terrestrial entities. In fact, Hacking explicitly argues against astronomical realism. The case at issue is the existence of gravitational lenses. In this paper, I question Hacking's chief witness for astronomical antirealism: the gravitational lens system “0957+ 561”. It will be shown that Hacking's argumentation is misleading. Discussing astronomical realism as theory realism, Hacking focuses on the question of how to infer the existence of gravitational lenses from the truth of gravitational lens theory. But neither the reconstruction of gravitational lensing in terms of inference to the best explanation (IBE) nor the argument of underdetermination are tenable under closer inspection. My thesis is that a realist account of gravitational lensing can be given by relying on observation, causal capacities and home truths.     

Testing problem-solving capacities: differences between individual testing and social group setting

Testing animals individually in problem-solving tasks limits distractions of the subjects during the test, so that they can fully concentrate on the problem. However, such individual performance may not indicate the problem-solving capacity that is commonly employed in the wild when individuals are faced with a novel problem in their social groups, where the presence of a conspecific influences an individual’s behaviour. To assess the validity of data gathered from parrots when tested individually, we compared the performance on patterned-string tasks among parrots tested singly and parrots tested in social context. We tested two captive groups of orange-winged amazons (Amazona amazonica) with several patterned-string tasks. Despite the differences in the testing environment (singly vs. social context), parrots from both groups performed similarly. However, we found that the willingness to participate in the tasks was significantly higher for the individuals tested in social context. The study provides further evidence for the crucial influence of social context on individual’s response to a challenging situation such as a problem-solving test.     

The more you ignore me the closer I get: An ERP study of evaluative priming

We used event-related brain potentials (ERPs) to investigate the various mental processes contributing to evaluative priming—that is, more positive judgments for targets preceded by affectively positive, as opposed to negative, prime stimuli. To ensure ecological validity, we employed a priori meaningful landscape pictures as targets and emotional adjectives as visual primes and presented both primes and targets for relatively long durations (>1 s). Prime-related lateralized readiness potentials (LRPs) revealed response priming as one source of the significant evaluative priming effect. On the other hand, greater right-frontal positive slow wave in the ERP for pictures following negative, as compared with positive, primes indicated altered impression formation, thus supporting automatic spreading activation and/or affect misattribution accounts. Moreover, target LRPs suggested conscious counter-control to reduce the evaluative priming net effect. Finally, when comparing prime ERPs for two groups of participants showing strong versus weak evaluative priming, we found strong evidence for the role of depth of prime processing: In the weak-effect group, prime words evoked an increased visual P1/N1 complex, a larger posterior P2 component, and a greater left-parietal processing negativity presumably reflecting semantic processing. By contrast, a larger medial-frontal P2/N2 complex in the strong-effect group suggested top-down inhibition of the prime’s emotional content. Thus, trying to ignore the primes can actually increase, rather than decrease, the evaluative priming effect.     

Attentional control in depression: A translational affective neuroscience approach

Translational research refers to the application of basic science to address clinical problems and acquire knowledge that can be used to guide and refine clinical practice. This special issue of Cognitive, Affective, & Behavioral Neuroscience seeks to explore and integrate some of the most promising findings offered by recent cognitive and affective neuroscience studies in hopes of filling the gap between basic and applied research, thereby heightening our understanding of vulnerability for depression. The studies presented in this special issue focus specifically on attentional processes. We solicited contributions from leading researchers involved in basic cognitive and neuroscience research investigating processes underlying depression-related disturbances in emotion processing. In this introductory article, we present an integrative overview to demonstrate how these specific contributions might be valuable for translational research.     

Developmental Changes In Switching Between Mental Task Sets: The Influence Of Verbal Labeling In Childhood

Age-related changes in the use of verbal processes for the efficient switching between tasks were investigated in 5-year-old children (N = 32, M age = 5.9 years) and 9-year-old children (N = 32, M age = 9.4 years). Task switching was assessed by means of a cued switching paradigm to examine two switching components: (a) to maintain and select and (b) to switch between task sets. The aim of this study is to determine (a) developmental changes in both switching components during childhood, (b) whether age-related changes in these components are influenced by verbalizations in terms of “thinking aloud” (Ericsson & Simon, 1993) during task performance, and (c) age changes in the content of the self-verbalizations. Results show an age-related impairment of the 5-year-old group on the level of task-set maintenance and selection. Children mainly verbalized the response labels. However, whereas 5-year-olds more often labeled their perceptions (Zelazo, 1999), 9-year-olds used language to maintain the currently relevant task set. Both age groups relied on the same verbal strategy facilitating task switching, supporting the view that language can be used to plan and guide actions (Luria, 1969).     

Emotion regulation in depression: Examining the role of cognitive processes

Sustained negative affect is a hallmark feature of depressive episodes. The ability to regulate emotional responses to negative events may therefore play a critical role in our understanding of this debilitating disorder. Individual differences in cognitive processes such as attention, memory, and interpretation may underlie difficulties in emotion regulation and numerous studies have identified cognitive biases and deficits that characterise depressed people. Few studies, however, have explicitly linked these biases to the difficulties in emotion regulation that are associated with depression. In this paper we discuss relations among cognitive processes and emotion regulation and review the depression literature to identify cognitive biases and deficits that may underlie maladaptive responses to negative events and mood states. Our review suggests that difficulties in the disengagement from negative material, memory biases, and deficits in cognitive control are frequently observed in depressive disorders and may be associated with the use of maladaptive emotion regulation strategies, such as rumination. These biases may also be related to difficulties implementing strategies that are effective for non-depressed people, such as recall of mood-incongruent material and reappraisal. Our review also suggests, however, that empirical studies linking cognitive biases and emotion regulation in depression are still largely missing and would present an important goal for future research in this area.