Heightened religiosity and epilepsy: evidence for religious-specific neuropsychological processes

It has been hypothesised that humans may have an innate neurologic tendency towards being religiously oriented, suggesting that we possess religious-specific neuropsychological processes. Persons with epilepsy provide a unique opportunity to study these relationships given the documented hyper-religious experiences observed with epilepsy. The current study evaluated 19 individuals with epilepsy to determine if epilepsy-related religious experiences (as measured by the Bear Fedio Inventory [BFI]) are reflective of a general increase in behaviours observed with epilepsy (e.g., philosophical thoughts, emotionality), or if they are reflective of a religious-specific orientation. Spearman correlations indicated that: (1) BFI religious-orientation scales are significantly related to philosophical concerns (i.e., nature of the universe), but not measures of emotionality and (2) BFI religious-orientation scales, but not philosophical or emotionality scales, are significantly associated with other commonly used measures of spirituality. These findings suggest that individuals may possess neuropsychological processes that are specific to religious orientations.     

Relationships Among Religiousness,Spirituality, and Health for Individuals with Stroke

The current study evaluated the relationships among spiritual beliefs, religious practices, physical health, and mental health for individuals with stroke. A cross-sectional analysis of 63 individuals evaluated in outpatient settings, including 32 individuals with stroke and 31 healthy controls was conducted through administration of the Brief Multidimensional Measure of Religiousness/Spirituality (BMMRS) and the Medical Outcomes Scale-Short Form 36 (SF-36). For individuals with stroke, the SF-36 General Mental Health scale was significantly correlated with only the BMMRS Religious and Spiritual Coping scale (r = .43; p < .05). No other BMMRS factors were significantly correlated with SF-36 mental or physical health scales. Non-significant trends indicated spiritual factors were primarily related to mental versus physical health. This study suggests spiritual belief that a higher power will assist in coping with illness/disability is associated with better mental health following stroke, but neither religious nor spiritual factors are associated with physical health outcomes. The results are consistent with research that suggests that spiritual beliefs may protect individuals with stroke from experiencing emotional distress.     

Re-conceptualizing the Factor Structure of the Brief Multidimensional Measure of Religiousness/Spirituality

Rationale This study attempted to differentiate statistically the spiritual and religious factors of the Brief Multidimensional Measure of Religiousness/Spirituality (BMMRS), which was developed based on theoretical conceptualizations that have yet to be adequately empirically validated in a population with significant health disorders. Participants One hundred sixty-four individuals with heterogeneous medical conditions [i.e., brain injury, spinal cord injury (SCI), cancer, stroke, primary care conditions]. Methods Participants completed the BMMRS as part of a pilot study on spirituality, religion, and physical and mental health. Results A principal components factor analysis with varimax rotation and Kaiser normalization identified a six-factor solution (opposed to the expected 8-factor solution) accounting for 60% of the variance in scores, labeled as: (1) Positive Spiritual Experience; (2) Negative Spiritual Experience; (3) Forgiveness; (4) Religious Practices; (5) Positive Congregational Support; and (6) Negative Congregational Support. Conclusions The results suggest the BMMRS assesses distinct positive and negative aspects of religiousness and spirituality that may be best conceptualized in a psychoneuroimmunological context as measuring: (a) Spiritual Experiences (i.e., emotional experience of feeling connected with a higher power/the universe); (b) Religious Practices (i.e., prayer, rituals, service attendance); (c) Congregational Support; and (d) Forgiveness (i.e., a specific coping strategy that can be conceptualized as religious or non-religious in context).     

Spatial and orientation specific integration in the tilt illusion

Lateral inhibition across a population of cells in visual cortex which are tuned to local orientation has been proposed and widely accepted as a basic process in the analysis of contour in the visual field. The tilt illusion is usually explained in terms of this inhibition. Experiments are reported which cast new light on the analysis of visual orientation. It is shown that tilt illusions may be obtained with very thin inducing annuli which are spatially remote from the test figure. In experiments in which remote crossed-grating plaids were used, an illusion which was pattern (global) rather than component (local) selective was seen. It is difficult to account for these observations in terms of local inhibitory mechanisms. Rather, the results support the existence of a secondary mechanism which is involved in basic orientation analytic processes. The relevance of these observations to models of visual contour analysis is discussed.     

Reinforcer control and human signal-detection performance

Eight humans participated in a two-choice signal-detection task in which stimulus disparity was varied over four levels. Two procedures arranged asymmetrical numbers of reinforcers received for correct left- and right-key responses (the reinforcer ratio). The controlled procedure ensured that the obtained reinforcer ratio remained constant over changes in stimulus disparity, irrespective of subjects' performances. In the uncontrolled procedure, the asymmetrical reinforcer ratio could covary with subjects' performances. The receiver operating characteristic (ROC) patterns obtained from the controlled procedure approximated isobias functions predicted by criterion location measures of bias. The uncontrolled procedure produced variable ROC patterns that were somewhat like the isobias predictions made by likelihood ratio measures of bias; however, the obtained reinforcer ratio became more extreme as discriminability decreased. The obtained pattern of bias was directly related to the obtained reinforcer ratio. This research indicates that criterion location measures seem to be preferable indices of response bias.     

Hypothalamic expression of NPY mRNA, vasopressin mRNA and CRF mRNA in response to food restriction and central administration of the orexigenic peptide GHRP-6

In this study, we examined the effects of restricted feeding and of central administration of an orexigenic ghrelin agonist GHRP-6 on peptide mRNA expression in the hypothalamus. We compared rats fed ad libitum with rats that were allowed food for only 2?h every day, and treated with a continuous chronic i.c.v. infusion of GHRP-6 or vehicle. Ad libitum fed rats exposed to GHRP-6 increased their food intake and body weight over 6 days, but, at the end of this period, neuropeptide Y mRNA expression in the arcuate nucleus was not different to that in control rats. By contrast, expression of neuropeptide Y mRNA in the arcuate nucleus was elevated in food-restricted rats, consistent with the interpretation that increased expression reflects increased hunger. However, neuropeptide Y mRNA expression was no greater in food-restricted rats infused with GHRP-6 than in food-restricted rats infused with vehicle; thus if the drive to eat was stronger in rats infused with GHRP-6, this was not reflected by higher levels of neuropeptide Y mRNA expression. Expression of vasopressin mRNA and corticotrophin releasing factor (CRF) mRNA in the paraventricular nucleus (PVN) was not changed by food restriction. GHRP-6 infusion increased CRF mRNA expression in ad libitum rats only.     

Psychopathic-like traits in childhood: conceptual and measurement concerns

Can psychopathy be identified in pre-adolescent children? This question has both theoretical and practical implications. So far, attempts to answer this question have been made by making downward extensions of symptoms of the disorder as found in adults. We argue that for the construct of psychopathy to be viable as a construct in childhood it is necessary to demonstrate that a coherent syndrome of symptoms can be identified during childhood. To achieve this it is necessary first to use a strong measurement model, and second to use developmentally informed conceptualizations of key constructs. In order to progress from the measurement perspective, it is necessary to demonstrate (i) configural invariance of symptoms across key ages, (ii) similar performance of age cognate symptoms across key ages, and (iii) stability of relative standing on the latent trait across age. Novel techniques including item response methods and structural equation modelling techniques are required. In this paper, we review the relevant literature and evaluate the strength, or otherwise, of the evidence that key traits of psychopathy can be observed in childhood.     

Two-dimensional tilt illusions induced by orthogonal plaid patterns: effects of plaid motion, orientation, spatial separation, and spatial frequency

Tilt illusions occur when a drifting vertical test grating is surrounded by a drifting plaid pattern composed of orthogonal moving gratings. The angular function of this illusion was measured as the plaid orientation (and therefore its drift direction) varied over a 180 degrees range. This was done when the test and inducing stimuli abutted and had the same spatial frequency, and when the test and inducing stimuli either differed in frequency by an octave, or were spatially separated by a 2 deg blank annulus, or both differed in frequency and were also separated by the annulus (experiments 1-4). The obtained angular function was virtually identical to that obtained previously with the rod and frame effect and other cases involving orthogonal inducing components, with evidence for illusions induced both by real-line components and by virtual axes of symmetry. Although the magnitude of the illusion was very similar in all four experiments, there was evidence to suggest that largest real-line effects occurred in the abutting same-frequency condition, with a pattern of results similar to that obtained previously with the simple one-dimensional tilt illusion. On the other hand, virtual-axis effects were more prominent with gaps between test and inducing stimuli. A fifth, repeated-measures, experiment confirmed this pattern of results. It is suggested that this pattern-induced tilt effect reflects both striate and extrastriate mechanisms and that the apparent influence of spatially distal virtual axes of symmetry upon perceived orientation implies the existence of AND-gate mechanisms, or conjunction detectors, in the orientation domain.