Fluctuations and phase symmetry in coordinated rhythmic movements

Pendular, clocking movements typify mammalian terrestrial locomotion. They can be investigated with a procedure in which people swing hand-held pendulums at the wrists, comfortably and rhythmically. Pendular, clocking behavior was examined for in-phase and out-of-phase coordinations. The periodic timing and powering of rhythmic movements in the comfort state follow from different laws (Kugler & Turvey, 1986). One law guides the assembling of the reference frame for "clocking." Another law guides the assembling of the muscular, escapement processes determining the cycle energy. Wing and Kristofferson's (1973) method for parsing periodic-timing variance into independent "clock" and "motor" sources was applied. Mean periodicity was unaffected by phase. "Clock" fluctuations, however, were larger out of phase than in phase. "Motor" fluctuations were indifferent to phase but reflected the departures of individual wrist-pendulum systems from their preferred periods. It appears that an intended phase relation is realized as a constraint on "clock" states. These states are more stable under the in-phase constraint than under the out-of-phase constraint.     

Multidimensional scaling reveals two dimensions of thermal pain

The Individual Differences Scaling (INDSCAL) model of multidimensional scaling was used to explore the dimensions of thermal pain. The observers made 66 similarity judgments to all pairs of 12 different thermal stimulus intensities ranging from zero to noxious. Analysis of the data revealed a two-dimensional group stimulus space. The major dimension ordered the stimuli with respect to their intensity. This quantitative, strength-of-sensation dimension may be interpreted as indicating how weak or strong a stimulus feels, apart from any secondary qualities of warmth or pain. The second dimension was related to the qualitative aspects of the stimuli. This bipolar dimension contained two attributes: a pain attribute ranging from just detectable warmth to painful, and a warm-hot attribute running from just detectable warmth to hot. This study demonstrates the utility of the INDSCAL approach to the understanding of pain and offers a new technique for answering the age-old question concerning the number and qualities of the dimensions underlying the pain experience.     

The facial muscle patterning of posed and imagery-induced expressions of emotion by expressive and nonexpressive posers

Much research on emotional facial expression employs posed expressions and expressive subjects. To test the generalizability of this research to more spontaneous expressions of both expressive and nonexpressive posers, subjects engaged in happy, sad, angry, and neutral imagery, and voluntarily posed happy, sad, and angry facial expressions while facial muscle activity (brow, cheek, and mouth regions) and autonomic activity (skin resistance and heart period) were recorded. Subjects were classified as expressive or nonexpressive on the basis of the intensity of their posed expressions. The posed and imagery-induced expressions were similar, but not identical. Brow activity present in the imagery-induced sad expressions was weak or absent in the posed ones. Both nonexpressive and expressive subjects demonstrated similar heart rate acceleration during emotional imagery and demonstrated similar posed and imagery-induced happy expressions, but nonexpressive subjects showed little facial activity during both their posed and imagery-induced sad and angry expressions. The implications of these findings are discussed.     

Sensitivity to thermal stimulation in prairie rattlesnakes (Crotalus viridis) after bilateral anesthetization of the facial pits

Six yearling prairie rattlesnakes (Crotalus viridis) were exposed to thermal stimuli prior to and after bilateral anesthetization of their facial pits with 2% xylocaine solution. This treatment eliminates trigeminally mediated electrophysiological responses of the pits to thermal stimulation. Nevertheless, the rattlesnakes continued to exhibit behavioral responses to thermal cues after anesthetization of the pits. An auxiliary infrared-sensitive system, nociceptors, or the common temperature sense could be responsible for these findings.     

Performance of normal and neurological mutant mice on radial arm maze and active avoidance tasks

The objectives of the present study are to assess the import of gene-imposed structural alterations on behavioral performance and obtain performance data preliminary to studies of experimental mouse chimera behavior. Reeler, staggerer, and weaver neurological mutant, and control B6C3 and ichthyosis mice were tested on radial arm maze and active avoidance tasks. Weaver mice had incapacitating seizures while performing the radial arm maze task and were, therefore, removed from further testing. Staggerer mice displayed a significant deficit on both tasks compared to control mice. Homozygous reeler mice (rl/rl) also had a significant deficit on the active avoidance task compared to +/rl control mice but not significantly poorer than ichthyosis mice. However, their performance on the radial arm maze task, while initially poor, improved so that they performed the task similar to wild-type controls. Three of the reeler mice reached criterion for solving the radial arm maze task. None of the staggerer mice reached criterion. These data are discussed in terms of the value of using neurologically mutant mice in dissecting structural-functional relationships. It is suggested that the behavior of these mutants might point toward specific components of cerebellar involvement in behavioral acts.     

The imperfect attainment of intimacy: a key concept in marital therapy

The intense though transient intimacy of romantic love is contrasted with the more durable and sustained intimacy of conjugal love. The latter, it is argued, requires that the partners have each attained an adequate degree of separateness and at the same time are able to allow themselves to become physically and emotionally close. Relationships which are not intimate are characterized by excessive degrees of dependence, directiveness or detachment. The equilibrium in a non-intimate relationship is maintained by fears in the respective partners about the other becoming too separate, too close, too influential, too assertive, too capable etc. Therapy involves persuading each to try cautiously giving ground in one direction whilst the other is giving ground in a complementary direction. Intimacy will follow if neither is too controlling from above nor too clinging from below and both partners are able to relate on an equal adult to adult basis.     

Substance P facilitation of memory: effects in an appetitively motivated learning task

Food deprived, heterogeneous strain (HS/IBG) mice were trained on two different discrimination tasks for food reinforcement. In one experiment animals were trained to make spatial discriminations in a T maze. Immediately after training they were given subcutaneous injections of either substance P (1 ng/g) or vehicle. Twenty-four hours later the animals were given reversal training in the same maze. The results showed that substance P-treated animals took significantly longer to acquire the reversal habit than did control mice. In a second experiment, animals were trained to make visual discriminations in a T maze. Immediately after reaching acquisition criterion animals were injected with either substance P (1 ng/g) or vehicle. Different groups of mice were retrained on the same task either 1, 2, 3, or 7 days after original learning. Savings scores were calculated and, at every interval, substance P-treated mice retained the task better than control animals. One interpretation of these data is that substance P-treated mice remembered the original task significantly better than vehicle-injected control animals.     

Patterns of memory failure after scopolamine treatment: implications for cholinergic hypotheses of dementia

To test the idea that scopolamine provides a suitable pharmacological model of the memory defects associated with cortical or subcortical dementias, we assessed memory on a battery of tasks in healthy young normal subjects who received 0.5 mg scopolamine, 0.1-0.2 mg glycopyrrolate or physiological saline, once each on three separate occasions, and compared the pattern of memory failure induced by scopolamine to that observed on the same tasks in patients with Alzheimer's disease (AD) or Huntington's disease (HD). In agreement with previous reports, scopolamine impaired acquisition and delayed recall of a 14-word list and disrupted retention on the Brown-Peterson distractor task, whereas the peripherally active anticholinergic glycopyrrolate was without effect. However, under scopolamine the pattern of errors made on these memory tasks was quite different from that seen in patients with AD. Scopolamine did not increase the number of false positive errors on delayed recognition of the word list and also failed to increase the number of prior-item intrusions on the Brown-Peterson task. Also, scopolamine did not impair learning of a symbol-digit paired-associate task, and did not reduce the number of words retrieved or increase the number of words repeated on a standardized verbal fluency test. When the effects of scopolamine on memory were compared to the pattern of impairments observed in demented patients with HD, several differences were found. Although scopolamine clearly produces deficits on some measures of anterograde memory, the present findings question whether anticholinergic drugs adequately mimic the full range of memory impairments observed in cortical or subcortical dementias.     

Sex differences in the effects of gonadectomy on amphetamine-induced rotational behavior in rats

The effects of gonadectomy on amphetamine-induced rotational behavior were studied in male and female rats. Different systemic doses were used to produce equivalent brain concentrations of the drug in each group, thereby controlling for sex differences in the metabolism of amphetamine. Ovariectomy of female rats significantly attenuated amphetamine-induced rotation, whereas castration of males was without effect. The results support the idea that in females, the endogenous gonadal hormones facilitate functional activity in the mesostriatal dopamine system.     

Impact of a preventive social problem solving intervention on children's coping with middle-school stressors

Children receiving 1 year or 1/2 year of a preventive social problem solving program in elementary school were compared with each other and with a no-treatment group upon entry into middle school. One year of training was significantly related to reductions in the severity of a variety of middle-school stressors. Most importantly, a clear mediating role for social problem solving (SPS) skills was found. Children lacking in SPS skills were more likely to experience intense stressors; however, possessing the skills was not necessarily predictive of adjustment to stressors. The results are discussed in terms of the implications of this asymmetry and the strong support given to the value of social problem solving as a preventive intervention for children.