Differential functioning of the Beck depression inventory in late-life patients: use of item response theory

The present analyses examined age-related measurement bias in responses to items on the revised Beck Depression Inventory (BDI) in depressed late-life patients versus midlife patients. Item response theory (IRT) models were used to equate the scale and to differentiate true-group differences from bias in measurement in the 2 samples. Baseline BDI data (218 late life and 613 midlife) were used for the present analysis. IRT results indicated that late-life patients tended to report fewer cognitive symptoms, especially at low to average levels of depression. Conversely, they tended to report more somatic symptoms, especially at higher levels of depression. Adjusted cutoff scores in the late-life group are provided, and possible reasons for age-related differences in the performance of the BDI are discussed.     

Effect of a total smoking ban in a maximum security psychiatric hospital

An archival study was performed in a maximum security forensic hospital to evaluate the effects of a total ban on smoking and all tobacco products. One hundred and forty patients were characterized as nonsmokers or light, moderate or heavy smokers. Patient records for the four weeks prior to the ban were compared with their records for the four weeks subsequent to the ban. Numbers of sick calls, total disruptive behaviors and verbal aggression declined markedly and significantly following the ban in those patients previously classified as moderate or heavy smokers. Weight increased significantly, but almost equally regardless of previous smoking status. Patients, and eventually staff, tolerated the smoking ban without significant negative effects. Patients relied very little on treatment modalities to alleviate nicotine withdrawal. Pre-ban apprehension by staff and patients dissipated with time after the smoking ban started.     

Learning where to look for danger: integrating affective and spatial information

Although not previously addressed by researchers of spatial cognition or affect, the combination of spatial and affective information is essential for many approach and avoidance behaviors, and thus for survival. We provide the first evidence that through incidental experience, people form representations that capture correlations between affective and spatial information. Participants were able to do so even when the correlation was weak, they were not told to look for the correlation, and the stimuli varied on multiple other dimensions besides valence. In addition, people were more sensitive to the presented correlation when stimuli were negative than when they were positive. This asymmetry in representation may stem from underlying differences in the activation functions for positive and negative hedonic information processing.     

The automatic evaluation of novel stimuli

From classic theory and research in psychology, we distill a broad theoretical statement that evaluative responding can be immediate, unintentional, implicit, stimulus based, and linked directly to approach and avoidance motives. This statement suggests that evaluative responses should be elicited by novel, nonrepresentational stimuli (e.g., abstract art, "foreign" words). We tested this hypothesis through combining the best features of relevant automatic–affect research paradigms. We first obtained explicit evaluative ratings of novel stimuli. From these, we selected normatively positive and negative stimuli to use as primes in a sequential priming paradigm. Two experiments using this paradigm demonstrated that briefly presented novel prime stimuli were evaluated automatically, as they facilitated responses to subsequently presented target stimuli of the same valence just as much as did pictures or names of real objects. A final experiment revealed that exposure to novel stimuli produces muscular predispositions to approach or avoid them.     

Multidimensional latent-construct analysis of children's social information processing patterns: correlations with aggressive behavior problems

Social information processing (SIP) patterns were conceptualized in orthogonal domains of process and context and measured through responses to hypothetical vignettes in a stratified sample of 387 children (50% boys; 49% minority) from 4 geographical sites followed from kindergarten through 3rd grade. Multidimensional, latent-construct, confirmatory factor analyses supported the within-construct internal consistency, cross-construct discrimination, and multidimensionality of SIP patterns. Contrasts among nested structural equation models indicated that SIP constructs significantly predicted children's aggressive behavior problems as measured by later teacher reports. The findings support the multidimensional construct validity of children's social cognitive patterns and the relevance of SIP patterns in children's aggressive behavior problems.     

Pharmacogenetics: ethical issues and policy options

Pharmacogenetics offers the prospect of an era of safer and more effective drugs, as well as more individualized use of drug therapies. Before the benefits of pharmacogenetics can be realized, the ethical issues that arise in research and clinical application of pharmacogenetic technologies must be addressed. The ethical issues raised by pharmacogenetics can be addressed under six headings: (1) regulatory oversight, (2) confidentiality and privacy, (3) informed consent, (4) availability of drugs, (5) access, and (6) clinicians' changing responsibilities in the era of pharmacogenetic medicine. We analyze each of these categories of ethical issues and provide policy approaches for addressing them.     

Fabry disease in genetic counseling practice: recommendations of the National Society of Genetic Counselors

The objective of this document is to provide health care professionals with recommendations for genetic counseling and testing of individuals with a suspected or confirmed diagnosis of Fabry disease, with a family history of Fabry disease, and those identified as female carriers of Fabry disease. These recommendations are the opinions of a multicenter working group of genetic counselors, medical geneticists, and other health professionals with expertise in Fabry disease counseling, as well as an individual with Fabry disease who is a founder of a Fabry disease patient advocacy group in the United States. The recommendations are U.S. Preventive Task Force Class III, and they are based on clinical experience, a review of pertinent English-language articles, and reports of expert committees. This document reviews the genetics of Fabry disease, the indications for genetic testing and interpretation of results, psychosocial considerations, and references for professional and patient resources. These recommendations should not be construed as dictating an exclusive course of management, nor does use of such recommendations guarantee a particular outcome. The professional judgment of a healthcare provider, familiar with the facts and circumstances of a specific case, will always supersede these recommendations.     

A crossmodal attentional blink between vision and touch

There is currently a great deal of interest regarding the possible existence of a crossmodal attentional blink (AB) between audition and vision. The majority of evidence now suggests that no such crossmodal deficit exists unless a task switch is introduced. We report two experiments designed to investigate the existence of a crossmodal AB between vision and touch. Two masked targets were presented successively at variable interstimulus intervals. Participants had to respond either to both targets (experimental condition) or to just the second target (control condition). In Experiment 1, the order of target modality was blocked, and an AB was demonstrated when visual targets preceded tactile targets, but not when tactile targets preceded visual targets. In Experiment 2, target modality was mixed randomly, and a significant crossmodal AB was demonstrated in both directions between vision and touch. The contrast between our visuotactile results and those of previous audiovisual studies is discussed, as are the implications for current theories of the AB.     

Postmodernism Versus Modernism: Rethinking Theoretical Tensions in Social Gerontology

The interconnection of social theory to social aspects of aging has grown in recent years. The theoretical movement entitled structured dependency, couched in social class analysis, has tended to ignore an understanding of aging identity, the body, cultural representations of aging, and positive images of aging, all of which are central features of an emerging postmodern paradigm in gerontological theory. This article argues that the concept of gender can form a useful bridge, a continuity, between structured dependency and postmodernism in theoretical gerontology. Unfortunately, the compartmentalization of these two conceptual approaches has made their links difficult to forge. This article attempts to take a first step in this direction by highlighting the way postmodern ideas can be used to understand a modernist issue—gender in a gerontological context. Also, focusing on the aging body as a primary form of analysis generates some novel insights into the importance of both the theoretical understanding and cultural representations of the body.