Cerebral white matter abnormalities and lifetime cognitive change: a 67-year follow-up of the Scottish Mental Survey of 1932

Cerebral white matter abnormalities relate to cognitive functioning in elders. We examine whether this association is (a) independent of mental ability in youth and (b) related to general and/or specific mental abilities. We retested 83 participants of the Scottish Mental Survey of 1932 on a battery of mental tests. Their brains were scanned by magnetic resonance imaging. Three independent ratings (Fazekas) were made of periventricular, and subcortical and deep white matter abnormalities. Structural equation models showed that, irrespective of brain location, white matter abnormalities contributed about 14% of cognitive function variance in old age. Some of this effect might be due to hypertension. This contribution is independent of mental function in early life and is associated with general cognitive ability.     

Prevention that works for children and youth. An introduction

The widespread implementation of effective prevention programs for children and youth is a sound investment in society's future. The most beneficial preventive interventions for young people involve coordinated, systemic efforts to enhance their social-emotional competence and health. The articles in this special issue propose standards for empirically supported programming worthy of dissemination and steps to integrate prevention science with practice. They highlight key research findings and common principles for effective programming across family, school, community, health care, and policy interventions and discuss their implications for practice. Recent advances in prevention research and growing support for evidence-based practice are encouraging developments that will increase the number of children and youth who succeed and contribute in school and life.     

Enhancing school-based prevention and youth development through coordinated social,emotional, and academic learning

A comprehensive mission for schools is to educate students to be knowledgeable, responsible, socially skilled, healthy, caring, and contributing citizens. This mission is supported by the growing number of school-based prevention and youth development programs. Yet, the current impact of these programs is limited because of insufficient coordination with other components of school operations and inattention to implementation and evaluation factors necessary for strong program impact and sustainability. Widespread implementation of beneficial prevention programming requires further development of research-based, comprehensive school reform models that improve social, health, and academic outcomes; educational policies that demand accountability for fostering children's full development; professional development that prepares and supports educators to implement programs effectively; and systematic monitoring and evaluation to guide school improvement.     

Heterosexist discrimination and relational sacrifice of same-sex couples

Drawing on the family stress process model and using data from 141 same-sex couples (N = 282 partners), we examined associations between heterosexist discrimination and relational sacrifices (i.e., willingness and behaviors). We also examined the moderating roles of both partners' internalized homophobia and state-level liberalism on same-sex marriage legalization. Actor-partner interdependence moderation models were conducted. Most of our findings supported hypotheses from the family stress process model. One individual's experiences of greater heterosexist discrimination were related to the partner's higher levels of sacrifice willingness and the individual's own higher frequency of sacrifice behaviors. Such associations emerged (a) among couples living in more liberal states that legalized same-sex marriage earlier, and (b) when the individual's partner reported lower levels of internalized homophobia. Yet the moderating role of an individual's internalized homophobia was the opposite of our hypothesis. When individuals reported high (versus low) internalized homophobia, individuals' experiences of more discriminative events were related to partners' higher levels of sacrifice willingness. Collectively, our study findings highlight that—when investigating how same-sex couples forge and maintain romantic bonds—researchers should consider their experiences in the social cultural context of heteronormativity, which includes the focus on discrimination, stigma, and affirmative laws and policies.     

The logical structure of Michael Williams's response to skepticism

This paper aims to reconstruct the overarching logical structure of Michael Williams's response to philosophical skepticism. One goal is to forestall overhasty dismissals of his position based on failures to understand the logical relations among his various anti-skeptical claims and arguments. In many places, Williams suggests that the strategy he calls “theoretical diagnosis” is sufficient to defuse the skeptical challenge and that, accordingly, his anti-skeptical strategy consists solely in developing theoretical diagnoses. According to the account developed here, this claim is misleading—in need of significant qualification, if not outright false. Even so, the paper concludes that, in its essentials, Williams's response is structurally sound, given his understanding of the problem posed by skepticism. The paper ends with a brief assessment of the merits of that response.     

Increased aggression after rapid eye movement sleep deprivation in Wistar rats is not influenced by reduction of dimensions of enclosure

Twelve female and twelve male Wistar rats were assigned to home groups, platform-control groups, and rapid eye movement sleep deprivation groups. The deprivation was performed with the cuff-pedestal method. Rats were tested in pairs in a shrinking chamber to increase proximity of the rats and to provoke interaction between them. An increase in boxing behavior was noted in the sleep-deprived groups. The result confirms that deprivation of rapid eye movement sleep increases aggressive behavior in the rat. However, this behavior is not influenced by the area of the testing arena. The sleep-deprived females explored each other more than the controls; the males' behavior did not differ in this respect. The amount of genital exploration decreased with diminishing area of enclosure, whereas boxing was not area dependent.     

A microcomputer-controlled system for measuring reactivity in small animals

A microcomputer-controlled system has been designed for measuring reactivity in small laboratory animals. This system uses a microcomputer to trigger an acoustic signal, which is fed to a loudspeaker through an audio power amplifier. An animal’s acoustic startle response is recorded using a moving-coil loudspeaker as a movement transducer. The transducer output is coupled to a peak-hold circuit that records the maximum voltage generated by the animal’s response. After conversion to digital form, the data for each stimulus presentation are stored and then printed when all trials have been completed.     

Effects of gender and topic on speech style

Male and female subjects described nine photographs that had been selected to be of interest to males, females, or both. The resulting speech samples were analyzed for the incidence of five features of word production and five features associated with a women's language (WL) speech style. Results showed that topic (photograph type) determined aspects of speech production. However, there were no gender differences in production or style. Correlations between dependent variables suggested that WL is a consistent set of features. Its use by both female and male speakers may reflect social uncertainty.The authors thank Janis Glenn and Cynthia Johnson for help in collecting and transcribing data.