Facing the Pariah of Science: The Frankenstein Myth as a Social and Ethical Reference for Scientists

Science and Engineering Ethics - Since its first publication in 1818, Mary Shelley’s Frankenstein; or, The Modern Prometheus has transcended genres and cultures to become a foundational myth...     

Regulating Research for the Decisionally Impaired: Implications for Mental Health Professionals

Mental health professionals, in fulfilling their different roles, often become involved with research protocols involving decisionally impaired current or prospective human subjects, many of whom are elderly. The opening section of this paper briefly describes the present regulatory environment regarding human subjects research, followed by an overview of the Institutional Review Board (IRB) process. There then ensues an enumeration of some of the general criticisms of the current regulatory scheme that have been enunciated recently. Particular concerns concerning decisionally impaired persons as research subjects are then addressed, referring when applicable to the recommendations made by the National Bioethics Advisory Commission (NBAC) in its 1998 report on this subject and the implications of those recommendations for mental health professionals.     

Acculturation and peritraumatic dissociation in young adult Latino survivors of community violence

This study examined the relationship between acculturation and peritraumatic dissociation in a sample of 304 physically injured Latino survivors of community violence. Item response theory analyses were conducted to document the measurement equivalence of English- and Spanish-language versions of a scale measuring peritraumatic dissociation. After establishing equivalence, structural equation modeling was used to determine the impact of acculturation on peritraumatic dissociation after controlling for other relevant covariates, including assault characteristics, intoxication before the assault, and trauma exposure history. Acculturation emerged as a significant and negative predictor of dissociation, so that high levels of acculturation were associated with low levels of peritraumatic dissociation. These findings offer a counterinstance to the emerging consensus that retention of Latin American cultural traditions serves to promote mental health.     

Shedding Light on the Difficulties and Challenges Experienced by Mothers of Infants

Adjustment to life with a newborn presents a variety of challenges, and some mothers experience postnatal disorders. It may be more normative for mothers to face less severe but nevertheless troubling difficulties. In this qualitative study, seven mothers (32–42 years) participated in individual interviews about the stresses and difficulties that they experienced with their infants. An interpretive analytical approach was used to identify the manifest difficulties and make sense of them in terms of three underlying psychological issues: (1) effectiveness as a mother; (2) relationship dynamics; and (3) sense of self. In spite of facing difficulties, mothers evaluated their overall experience as positive. We report on the main adjustments and changes that facilitated their way through the challenges.     

Climbing the Ladder: Experience with Developing a Large Group Genetic Counselor Career Ladder at Children’s National Health System

Children’s National Health System (CNHS) is a not-for-profit pediatric hospital that employs around twenty genetic counselors in a range of specialties, including clinical pediatric, neurology, fetal medicine, research, and laboratory. CNHS lacked a structured system of advancement for their genetic counselors; therefore, a formal career ladder was proposed by the genetic counselors based on years of experience, responsibility, and job performance. This career ladder utilized monetary, academic, and seniority incentives to encourage advancement and continue employment at CNHS. The creation and ultimate approval of the career ladder required direct input from genetic counselors, Department Chairs, and Human Resource personnel. The establishment of a genetic counselor career ladder at CNHS will hopefully benefit the profession of genetic counselors as a whole and allow other facilities to create and maintain their own career ladder to meet the needs of the growing, competitive, field of genetic counseling.     

Does motor interference arise from mirror system activation? The effect of prior visuo-motor practice on automatic imitation

Action perception may involve a mirror-matching system, such that observed actions are mapped onto the observer’s own motor representations. The strength of such mirror system activation should depend on an individual’s experience with the observed action. The motor interference effect, where an observed action interferes with a concurrently executed incongruent action, is thought to arise from mirror system activation. However, this view was recently challenged. If motor interference arises from mirror system activation, this effect should be sensitive to prior sensorimotor experience with the observed action. To test this prediction, we measured motor interference in two groups of participants observing the same incongruent movements. One group had received brief visuo-motor practice with the observed incongruent action, but not the other group. Action observation induced a larger motor interference in participants who had practiced the observed action. This result thus supports a mirror system account of motor interference.     

An Evaluation of the Relation Between Distress Tolerance and Posttraumatic Stress within a Trauma-Exposed Sample

The present investigation examined the incremental associations between distress tolerance, or the perceived capacity to tolerate emotional distress, and global posttraumatic stress symptom severity as well as symptom cluster severity, beyond the variance accounted for by number of trauma exposure types and negative affectivity. The sample consisted of 140 adults (72 women; M _age = 25.9, SD = 11.1) who endorsed exposure to traumatic life events, as defined by posttraumatic stress disorder diagnostic criterion A (American Psychiatric Association 2000). Participants did not meet diagnostic criteria for current axis I psychopathology. Distress tolerance demonstrated significant incremental associations with global posttraumatic stress symptom severity (p < .01) as well as re-experiencing (p < .05), avoidance (p = .05), and hyperarousal (p < .001) symptom cluster severity. Given the cross-sectional study design, causation cannot be inferred. Theoretical implications and future directions for better understanding associations between distress tolerance and posttraumatic stress are discussed.     

Decision-making under uncertainty: biases and Bayesians

Animals (including humans) often face circumstances in which the best choice of action is not certain. Environmental cues may be ambiguous, and choices may be risky. This paper reviews the theoretical side of decision-making under uncertainty, particularly with regard to unknown risk (ambiguity). We use simple models to show that, irrespective of pay-offs, whether it is optimal to bias probability estimates depends upon how those estimates have been generated. In particular, if estimates have been calculated in a Bayesian framework with a sensible prior, it is best to use unbiased estimates. We review the extent of evidence for and against viewing animals (including humans) as Bayesian decision-makers. We pay particular attention to the Ellsberg Paradox, a classic result from experimental economics, in which human subjects appear to deviate from optimal decision-making by demonstrating an apparent aversion to ambiguity in a choice between two options with equal expected rewards. The paradox initially seems to be an example where decision-making estimates are biased relative to the Bayesian optimum. We discuss the extent to which the Bayesian paradigm might be applied to the evolution of decision-makers and how the Ellsberg Paradox may, with a deeper understanding, be resolved.