Regional cerebral glucose metabolism in aphemia: A case report

Local cerebral metabolism was determined in a patient suffering aphemia following cerebral infarction using the 18FDG-PET technique. The syndrome was characterized by profound ictal nonfluency with sparing of other language functions. Speech subsequently improved so that content and grammar were appropriate but mild dysprosody persisted. Conventional CT showed no lesion of the left hemisphere while PET revealed a discrete focus of hypometabolism on the left which partially resolved on serial studies. The metabolic lesion could be localized to the region of the inferior precentral gyrus and the adjacent subcortical space.     

Lexical contribution to nonword-repetition effects: Evidence from event-related potentials

Two experiments investigated the modulation of event-related potentials (ERPs) by the repetition of orthographically legal and illegal nonwords. In Experiment 1, subjects silently counted occasional words against a background of nonwords, a proportion of which were repetitions of an immediately preceding legal or illegal item. ERPs to repeated legal items showed a sustained, topographically diffuse, positive-going shift. In contrast, repeated illegal nonwords gave rise to ERPs showing a smaller and temporally more restricted positive-going modulation. In an attempt to equalize depth of processing across legal and illegal nonwords, subjects in Experiment 2 were required to count items containing a nonalphabetic character against the same background of nonword items. ERPs to repeated legal items showed a modulation similar to, although smaller than, that found in Experiment I, but no effects of repetition were observed in the ERPs to the illegal nonwords. It was concluded that the effects of repeating nonwords, at least as manifested in concurrently recorded ERPs, differ as a consequence of whether items can access lexical memory, and that this is inconsistent with the attribution of such effects solely to the operation of episodic memory processes.     

The role of structural context in perception: Syntax in the recognition of algebraic expressions

Two character-identification experiments investigated the function of structural context during the processing of briefly exposed algebraic strings. Neither experiment prodded evidence to support the notion of an algebra-superiority effect, a contextually driven enhancement of the recognition of specific algebraic characters. However, the results of Experiment 2 indicate that the structure of algebra does provide information at the level of a character’s categorical denomination. These findings suggest that the parsing of an algebraic string includes a level of processing in which its structural context places restrictions on the denominations of its symbols. A processing model of algebraic perception is proposed that incorporates these syntactic constraints—constraints that appear to be independent of feature-based character identification processes.     

J. M. Keynes' ‘theory of evidential weight’: Its relation to information processing theory and application in The General Theory

The conclusions derived by Keynes in his Treatise on Probability (1921) concerning induction, analogical reasoning, expectations formation and decision making, mirror and foreshadow the main conclusions of cognitive science and psychology.The problem of weight is studied within an economic context by examining the role it played in Keynes' applied philosophy work, The General Theory (1936). Keynes' approach is then reformulated as an optimal control approach to dealing with changes in information evaluation over time. Based on this analysis the problem of inductive justification, from a societal perspective, is not, What can we rationally believe will occur in the economic future, given our past experiences? but Can we make the future so as to attain specific economic goals with practical certainty? An answer requires that restrictions be placed on the methodological individualist approach and the acceptance of a restricted holistic approach.     

Psychotropic drug treatment among learning-disabled,educable mentally retarded,and seriously emotionally disturbed students

Psychotropic drug treatment in learning-disabled (LD), educable mentally retarded (EMR), and seriously emotionally disturbed (ED) children and adolescents receiving public school special education services was examined. The findings indicated that while treatment prevalence rates for EMR and ED groups were comparable, the rate for LD students was much lower. In the LD sample, pharmacotherapy was associated with higher ratings of behavioral deviance, longer placement in special education, less social integration, and greater peer rejection, which suggests that symptom severity is an important determiner of pharmacotherapy in this population.     

The word frequency effect in lexical decision: Finding a frequency-based component

Subjects making lexical decisions are reliably faster in responding to high-frequency words than to low-frequency words. This is known as the word frequency effect. We wished to demonstrate that some portion of this effect was due to frequency differences between words rather than to other dimensions correlated with word frequency. Three groups of subjects (10 engineers, 10 nurses, and I0 law students) made lexical decisions about 720 items, half words and half nonwords, from six different categories (engineering, medical, low-frequency nontechnical, medium-frequency nontechnical, and two groups of high-frequency nontechnical). Results of two analyses of variance revealed a crossover interaction such that engineers were faster in responding to engineering words than to medical words, whereas nurses were faster in responding to medical words than to engineering words. The engineering and medical words were equally long and equally infrequent by standard word counts. We take this as support for a frequency-based component in the word frequency effect. The practical implications of this research for estimating the readability of technical text are discussed.     

A comparison of the relative efficacy of self-control therapy and a behavioral problem-solving therapy for depression in children

Twenty-nine children 9 to 12 years old who were identified as moderately to severely depressed using the Children's Depression Inventory were randomly assigned to either a self-control, behavioral problem-solving, or waiting list condition. The self-control treatment focused on teaching children self-management skills. The behavioral problem-solving therapy consisted of education, self-monitoring of pleasant events, and group problem solving directed toward improving social behavior. Subjects were assessed pre-and posttreatment and at 8-week follow-up with multiple assessment procedures and from multiple perspectives. At posttreatment, subjects in both active treatments reported significant improvement on self-report and interview measures of depression while subjects in the waiting list condition reported minimal change. Results were maintained at follow-up. The general success of the experimental treatments was discussed and recommendations for further treatment components were provided.Second authorship on this article is shared by Drs. Reynolds and Kaslow. The authors would like to thank Mr. Ed Guzwieski, Principal, and the teachers of Oregon Middle School for their cooperation with this study. The authors also would like to thank Mary Wysopal for conducting the posttreatment and follow-up interviews, and Carol Fairbanks for rating the audiotapes.     

Crime and amnesia: A review

The present article reviews amnesia for criminal offenses. It discusses the organic disorders most likely to be implicated, and the nature and differentiation of psychogenic amnesia. With the exception of alcohol and drug intoxication, organic dysfunction is a rare (though important) cause of amnesia for crime. Likewise, fugue states may occasionally be triggered by an offence, but are a very rare cause of the amnesia claimed by offenders. Amnesia is most commonly seen in homicide cases, in which it is claimed by 25% to 45% of offenders, but it occurs also in other types of violent crime, and occasionally in nonviolent crime. It arises in states of extreme emotional arousal, in alcoholic intoxication, and in states of florid psychosis; and it is also associated with depressed mood. Various methods have been advocated for the differentiation of genuine amnesia from deliberate simulation: this distinction can be difficult, but it is noticeable that many amnesic subjects either have reported the crime themselves or have made no attempt to conceal it. The nature of the deficit in this type of amnesia, and its implications for assessment, are also discussed.     

A structural model for postpartum responses to the somatic and cognitive items on the Beck Depression Inventory

A distinction can be drawn between those items on the Beck Depression Inventory (BDI) that reflect mainly cognitive and emotional symptoms and those that reflect somatic symptoms. Responses to the BDI were obtained from women at 3, 6, 9, and 24 weeks postpartum. The covariances of cognitive and somatic symptom scores across the four time points were closely fit by a structural equations model referred to as the simplex. The modeling indicates that earlier cognitive scores directly predict later somatic scores but that early somatic scores do not directly predict later cognitive scores. Other data confirm the results.Much of this research was supported while the first author was an NIMH Fellow at the University of Iowa (MH15168).