What gene-environment interactions can tell us about social competence in typical and atypical populations

Social competence is a complex human behaviour that is likely to involve a system of genes that interacts with a myriad of environmental risk and protective factors. The search for its genetic and environmental origins and influences is equally complex and will require a multidimensional conceptualization and multiple methods and levels of analysis. Behavioural genetic research can begin to address the fundamental yet complex question of how children develop social competence by uncovering the various influences on social development and disentangling variance due to multiple genes, environments and experiences. In this paper, we review the current status of research on sociability, face recognition, emotion recognition, and theory of mind (TOM)--well defined and measured constructs that are likely to be useful indices for detecting genetic and environmental influences on social competence. We also propose specific milestones as indices of further progress in the field: the development of an operational definition of the construct of social competence, the identification of social endophenotypes-psychological processes that are validly and reliably measured components of social competence, and improving specificity and homogeneity with regard to social endophenotypes within a population of study by employing 'extreme social phenotypes'. These efforts will lead to a better understanding of the specific contributions to the normal variation of social competence in the general population as well as to atypical social development.     

Adjudicative competence and comprehension of Miranda rights in adolescent defendants: a comparison of legal standards

Currently, there is considerable variability and ambiguity in legal standards pertaining to juveniles' comprehension of Miranda rights and their adjudicative competence. This study investigated rates of impairment under various proposed legal standards. One hundred and fifty-two young defendants aged 11-17 were assessed with Grisso's Miranda Instruments and the Fitness Interview Test-Revised. While over half of defendants aged 15 and under were classified as impaired in adjudicative capacities when adult norms were applied, significantly fewer adolescents were classified as impaired when adolescent norms were applied or a standard of "basic understanding and communication." Also, while over half of defendants aged 15 and under were classified as impaired in their comprehension of Miranda rights when both understanding and appreciation of Miranda rights were required, significantly fewer youth were classified as being impaired when only understanding was required. The implications of these findings are discussed.     

The neural consequences of semantic richness: when more comes to mind, less activation is observed

Some concepts have richer semantic representations than others. That is, when considering the meaning of concepts, subjects generate more information (more features, more associates) for some concepts than for others. This variability in semantic richness influences responses in speeded tasks that involve semantic processing, such as lexical decision and semantic categorization tasks. It has been suggested that concepts with richer semantic representations build stronger attractors in semantic space, allowing faster settling of activation patterns and thus faster responding. Using event-related functional magnetic resonance imaging, we examined the neural activation associated with semantic richness by contrasting activation for words with high and low numbers of associates in a semantic categorization task. Results were consistent with faster semantic settling for words with richer representations: Words with a low number of semantic associates produced more activation than words with a high number of semantic associates in a number of regions, including left inferior frontal and inferior temporal gyri.     

Jumping to interpretations: social anxiety disorder and the identification of emotional facial expressions

A small body of research suggests that socially anxious individuals show biases in interpreting the facial expressions of others. The current study included a clinically anxious sample in a speeded emotional card-sorting task in two conditions (baseline and threat) to investigate several hypothesized biases in interpretation. Following the threat manipulation, participants with generalized social anxiety disorders (GSADs) sorted angry cards with greater accuracy, but also evidenced a greater rate of neutral cards misclassified as angry, as compared to nonanxious controls. The controls showed the opposite pattern, sorting neutral cards with greater accuracy but also misclassifying a greater proportion of angry cards as neutral, as compared to GSADs. These effects were accounted for primarily by low-intensity angry cards. Results are consistent with previous studies showing a negative interpretive bias, and can be applied to the improvement of clinical interventions.     

The Effect of Disruptions During Counseling on Recall of Genetic Risk Information: The Case of Cystic Fibrosis

Genetic counseling is a communication process with two main functions: information provision and supportive counseling. The information transmission function may be compromised by disruptions that occur during counseling. At least two mediators are possible: (a) disruptions may interfere with memory by creating distractions and divided attention during encoding or (b) disruptions may degrade the flow of interaction which requires that participants engage in conversation repair rather than the task at hand. This study examined both alternatives in a group of parents (N=20 families, 40 individual parents) whose infant had received a newborn screening for cystic fibrosis (CF). Upon arrival at the hospital, each parent completed a questionnaire designed to assess his or her knowledge of CF. Their interaction with the genetic counselor was videotaped and coded for the presence of disruptions. Six weeks after the counseling, parents again completed the knowledge measure. The data showed a direct negative effect for disruptions during counseling on memory for CF-related risk information six weeks later. Disruptions also produced the anticipated effect on conversation, but counter to expectations, interruptions of conversation flow was positively associated with knowledge at time 2.     

Life-long environmental enrichment differentially affects the mnemonic response to estrogen in young, middle-aged, and aged female mice

The present study was designed to examine whether life-long exposure to standard or enriched housing affects the ability of estrogen to improve spatial and object memory throughout the lifespan. Three-week-old female mice were maintained in standard or enriched housing up to and through ovariectomy and behavioral testing at 5, 17, or 22 months of age. Spatial memory was tested in the Morris water maze and object memory was tested using an object recognition task. Immediately after training each day, mice were injected intraperitoneally with vehicle or 0.2 mg/kg 17beta-estradiol. Among young females, object recognition was enhanced by estradiol alone, an effect that was reduced by enrichment. In contrast, spatial water maze performance was impaired by estradiol alone, but improved by the combination of both estradiol and enrichment. At middle-age, object recognition was enhanced by estradiol or enrichment alone, and the combination of both treatments. Spatial memory in the water maze was also improved by both treatments at middle-age, but the beneficial effects of estradiol were limited to standard-housed females. Finally, whereas enrichment in aged females significantly enhanced performance in both tasks, estradiol had no effect at this age in either task. In total, the data indicate that life-long enrichment can significantly alter the extent to which estradiol affects memory in mice throughout the lifespan. Importantly, the interaction between these treatments is highly dependent on age and type of memory tested.     

ASPECT-SWITCHING AND VISUAL PHENOMENAL CHARACTER

John Searle and Susanna Siegel have argued that cases of aspect-switching show that visual experience represents a richer range of properties than colours, shapes, positions and sizes. I respond that cases of aspect-switching can be explained without holding that visual experience represents rich properties. I also argue that even if Searle and Siegel are right, and aspect-switching does require visual experience to represent rich properties, there is reason to think those properties do not include natural-kind properties, such as being a tomato.     

Dependency Stereotypes and Aging: The Implications for Getting and Giving Help in Later Life

Older adults are often stereotyped as dependent on others. This study explored how seeing an older adult receiving help triggers the dependency stereotype, by examining perceptions of older and younger adults helping and being helped by others. Participants (183 younger and older adults) read vignettes of young and old people helping others and rated the helpers and helpees on 2 variables: one a composite of dependency and capability; and the other composed of thoughtfulness, generosity, and unselfishness (i.e., considerateness). Participants rated older helpees as dependent, no matter who helped them. Younger helpers and those who helped the elderly rated high on considerateness. Females rated helpers more positively than did males. Implications of these findings for older adults are discussed.     

Using the MMPI-2 to Predict Symptom Reduction During Psychotherapy in a Sample of Community Outpatients

In the present study, potential MMPI-2 predictors of psychotherapy outcome were examined in a community clinical sample of 51 patients seeking treatment at a university training clinic. Results indicated that particular MMPI-2 scales (L, F, Pd, Pa, Sc, Trt) were the most predictive of initial levels of patient distress, whereas three other clinical scales (Hs, D, Hy) were significantly associated with actual symptom reduction over time. The clinical implications of these data include the use of the MMPI-2 in clinical practice as a means to frame the provision of direct feedback to patients regarding the likelihood of treatment response, which in turn, might actually have therapeutic benefits. The limitations of the study are reviewed and suggestions for future research are offered, including the potential use of widely known and utilized instruments in helping to predict response to psychotherapy.