Effects of neonatal treatment with 1-(2,5-dimethoxy-4-lodophenyl)-2 aminopropane HCI (DOI) and ritanserin on agonistic behavior in adult male and female rats

The role played by the neonatal 5-hydroxytryptamine (5HT) system in the organization and sexual differentiation of adult agonistic behavior was investigated in rats. Focus was on the 5HT2 receptor subtype, which has been demonstrated to be involved in agonism control in the adult. 5HT2 activity was experimentally manipulated by administration of a specific agonist [1-(2, 5-dimethoxy-4-iodophenyl)-2-aminopropane HCl (DOI)] or antagonist (ritanserin) during the second week of life, when serotonin is known to concur to anatomical and behavioral sexual differentiation. Interactions between early 5HT2 activity, genetic sex, and neonatal circulating testosterone (T) were studied by administering the ligands to males, females, and androgenized females. At adulthood, the animals were tested for both aspects of agonism, i. e., aggression and defense, in a 20-min confrontation with an unfamiliar conspecific of the same sex, age, body weight, and social experience. Neonatal administration of the 5HT2 antagonist ritanserin increased aggression independently of sex; it also increased defense, but this effect was confined to males. The agonist DOI had no effect on aggression, but enhanced defense in males and androgenized females, with an effect which depended therefore more on neonatal T than genetic sex. Females appeared in general less sensitive to neonatal 5HT2 manipulation than both androgenized females and males; this suggests that neonatal T is crucial for experimental modifications of neonatal 5HT2 activity to have any consistent effect on adult agonistic behavior. On the other hand, effects observed in males and androgenized females were dependent on the behavior considered and the drug administered. This was especially evident for defense, enhanced by ritanserin in males only, and in both males and androgenized females by DOI. Neonatal 5HT2 activity seems therefore to play a role in the modulation of adult agonistic behaviors, which depends on the behavior considered and is under multiple control of genetic sex and hormonal neonatal substrate. © 1994 Wiley-Liss, Inc.     

Readers and service commissioners require clear financial disclosures: Comment on innovation,research integrity,and change: A conflict of interest management framework for program developers (Sanders et al., 2019)

Sanders et al.'s proposal for a management framework for conflicting interests among program developers is very welcome. The underlying principles of such a framework must nevertheless prioritise the need for researchers and commissioners of services to make objective assessments of the impact of interventions reported in journal articles. This is particularly important in the field of randomised trials which may influence public sector expenditure. Using a strict definition derived from known financial conflict of interest, we have demonstrated that child-based effect sizes are much lower for independent studies than for studies with developer involvement. On this basis, we propose that journals publishing evaluations of psychosocial interventions should agree a standardised format for declarations of conflicts of interest based on that recommended by the International Committee of Medical Journal Editors.     

Defensive aggression in terns: Effect of species,density, and isolation

Defensive aggression was examined in seven species of terns during the hatching period when young are most vulnerable and adults most responsive. Aggression toward an unfamiliar person varied with respect to species, flush distance, approach distance, number of birds overhead and diving, and number of dives per 2 min for all birds and the nest owner. Defensive aggression involved birds circling over and diving at the experimenter. Generally, flush distance was negatively correlated with nest density, while the number of birds diving was positively correlated with the nest density. The number of birds diving was positively related to the number of dives, dives by the owner, and the number overhead.     

Prior Allegations of Harassment Impact Mock Jurors’ Perceptions of Sexual Harassment in a Criminal Trial

The current study examined factors that may influence jurors’ judgments in a criminal sexual harassment case with Canadian undergraduate students. Undergraduate students (n?=?268) examined whether defendant’s gender, victim’s gender, and whether the victim had made similar accusations in the past were influential in mock jurors’ judgments. Participants read a case summary describing an alleged sexual harassment and answered questions concerning defendant’s guilt, defendant’s culpability, and perceptions of the victim. Additionally, attitudes concerning sexual harassment and sexism were measured. The presence of prior allegations was a driving force in mock juror decisions, with mock jurors providing more guilty verdicts, more favorable perceptions of the victim, and less favorable perceptions of the defendant when no prior allegations of harassment had been made by the victim. The results of the current study suggest that the presence of prior allegations have a large impact on mock jurors’ decisions, suggesting that prior allegations may need to be considered more closely in court before they can be used as evidence.

     

Making Americans Feel Great Again? Personal Significance Predicts Political Intentions of Losers and Winners of the 2016 U.S. Election

Reactions of losers and winners of political elections have important consequences for the political system during times of power transition. In four studies conducted immediately before and after the 2016 U.S. presidential elections, we investigated how personal significance induced by success or failure of one's candidate is related to hostile versus benevolent intentions toward political adversaries. We found that the less significant supporters of Hillary Clinton and supporters of Donald Trump felt after an imagined (Study 1A) or actual (Study 2) electoral failure the more they were willing to engage in peaceful actions against the elected president and the less they were willing to accept the results of the elections. However, while significance gain due to an imagined or actual electoral success was related to more benevolent intentions among Clinton supporters (Study 1B), it was related to more hostile intentions among Trump supporters (Studies 1B, 2, and 3).     

New Directions in the Conceptualization and Assessment of Personality—A Dynamic Systems Approach

In this paper, we demonstrate how an integrative approach to personality—one that combines within-person and between-person differences—can be achieved by drawing on the principles of dynamic systems theory. The dynamic systems perspective has the potential to reconcile both the stable and dynamic aspect of personality, it allows including different levels of analysis (i.e. traits and states), and it can account for regulatory mechanisms, as well as dynamic interactions between the elements of the system, and changes over time. While all of these features are obviously appealing, implementing a dynamic systems approach to personality is challenging. It requires new conceptual models, specific longitudinal research designs, and complex data analytical methods. In response to these issues, the first part of our paper discusses the Personality Dynamics model, a model that integrates the dynamic systems principles in a relatively straightforward way. Second, we review associated methodological and statistical tools that allow empirically testing the PersDyn model. Finally, the model and associated methodological and statistical tools are illustrated using an experience sampling methodology data set measuring Big Five personality states in 59 participants (N = 1916 repeated measurements). © 2020 The Authors. European Journal of Personality published by John Wiley & Sons Ltd on behalf of European Association of Personality Psychology     

Marital interaction of agoraphobic women: a controlled,behavioral observation study

Married couples with a female agoraphobic spouse (n = 22) were compared with demographically similar community control couples (n = 21) on self-report and observational measures of marital interaction. Consistent with hypotheses, husbands of agoraphobic women were more critical of their wives than were control husbands, and clinical couples were less likely to engage in positive problem solution than control couples. Contrary to hypothesis, clinical husbands were not less supportive than control husbands. Where general measures of marital distress were concerned, clinical couples, relative to control couples, evinced more distress by self-report, by their higher rate of negative nonverbal behavior, and by their longer sequences of negative exchanges.