Effect of sulpiride on amphetamine-induced activity and stereotyped locomotion

To investigate the hypothesis that sulpiride potentiates stereotyped locomotion at an intermediate dose of amphetamine, rats were assigned to one of four treatment groups (n=7 per group): vehicle + saline; 20 mg/kg sulpiride + saline; vehicle + 3.5mg/kg amphetamine; 20 mg/kg sulpiride + 3.5 mg/kg amphetamine. An automated tracking system was used to record distance moved and sequences of movements between quadrants in a circular open-field. The results showed that amphetamine increased horizontal distance moved, and increased the number and proportion of thigmotaxic trips around the perimeter of the apparatus. Sulpiride reduced amphetamine-induced hyperactivity and the number of perimeter trips, but had no effect on the proportion and maximum run length of perimeter trips. Thus sulpiride reduces the hyperactivity produced by an intermediate dose of amphetamine, but does not appear to affect the stereotyped nature of locomotion under the drug.     

Switched-words skepticism: A case study in semantical anti-skeptical argument

Conclusion Semantically based arguments play a crucial role in responding to a certain sort of skeptical strategy, a strategy that is widely generalizable, and which is otherwise peculiarly difficult to answer. The anti-skeptical arguments we have been studying do this while avoiding reliance on the insupportable linguistic claims of co-optionism. Instead, they rely on the prevalence of a certain plausible general feature of the semantics of our language. Not surprisingly, this epistemologically important feature is itself frankly epistemological: in essence, we must (typically) be able to tell what a word refers to, in a way independent of the beliefs we use the word to express. In addition to rendering valuable anti-skeptical service, then, the arguments we have been studying display an additional dimension of interest, for they help to illuminate the ways in which our knowledge of the world at large is bound up with our knowledge of a particular part of that world — the language we use to describe it.I would like to thank Joseph Almog, Richard Healey, David Kaplan, Hilary Kornblith, Arthur Kuflik, William E. Mann, Derk Pereboom, George Sher, and a referee forPhilosophical Studies for helpful discussions and comments on earlier drafts.     

Luria's Neuropsychological Evaluation in the Nordic Countries

The publication of Luria's Neuropsychological Investigation (LNI) by Christensen in 1975 introduced Luria's evaluation procedures to worldwide neuropsychology. The LNI demonstrated the benefit of a thorough qualitative analysis of an individual patient's functioning as well as the usefulness of a comprehensive theory of brain functioning. This article reviews the experiences that led to the development of the LNI, discusses its use and extension in Scandinavian countries, and presents clinical and research applications of the LNI in diagnosis and rehabilitation. A series of case examples provides justification and validity for the continued use of the LNI and related procedures. Discussion of the advantages and disadvantages of the LNI and consideration of possible modifications of the procedures and interpretative methods provide the rationale for continued development of Luria's approach.     

Reviews of current books

Pastoral Psychology -     

Relating a Social Influence Model to the Role of Acculturation in Substance Use Among Latino Adolescents1

This study examined determinants of substance use derived from the theory of planned behavior as influenced by acculturation. Latino adolescents (n= 448) completed measures of attitudes, subjective norms, perceived behavioral control, intentions toward substance use, and 2 acculturation components. The degree to which Latino adolescents were exposed to as well as use Spanish was unrelated to determinants of future substance use, whereas the degree to which they interact with non-Latino peers exerted a protective effect regarding future substance use. However, both acculturation components influenced the extent social influence determinants predicted future substance use. Intervention strategies may need to consider acculturation in order to effectively direct resources toward those psychosocial determinants of substance use of greatest relevance to Latino populations.     

Observed communication and associations with satisfaction during traditional and integrative behavioral couple therapy

To investigate changes in couple communication and potential mechanisms of change during treatment, 134 distressed couples, who were randomly assigned to either traditional or integrative behavioral couple therapy (TBCT; IBCT), were observed in relationship and personal problem discussions prior to and near the end of treatment. Analyses were conducted using the Hierarchical Linear Modeling program. Over the time in therapy, during relationship problem discussions, positivity and problem solving increased while negativity decreased. Compared to IBCT, TBCT couples had the largest gains in positivity and reductions in negativity. During personal problem discussions, negativity decreased, while withdrawal increased and positivity decreased. TBCT couples had larger declines in negativity. In both discussion types, increases in marital satisfaction were associated with increases in positivity and problem solving. Declines in marital satisfaction were associated with increased negativity during relationship problem interactions and increased withdrawal during personal problem interactions. However, no treatment differences in these associations were found. Differences in rule-governed and contingency-shaped behavior change strategies between the two therapies and implications of findings are discussed.     

Activating Basic Category Exemplars in Sentence Contexts: A Dynamical Account

This paper examines the influence of context on the processing of category names embedded in sentences. The investigation focuses on the nature of information available immediately after such a word is heard as well as on the dynamics of adaptation to context. An on-line method (Cross Modal Lexical Priming) was used to trace how this process unfolds in time. We found that the information available immediately after a category word is presented is not altered by the sentence context in which the word is immersed. Rather, the structure of availability of particular exemplars of the category resembles the typicality structure of a conceptual representation. The adaptation to context occurs later (between 300 and 450 ms after the category word) and takes the form of a rapid reorganization of the structure rather than a gradual activation of a contextually relevant exemplar. We claim that such data is best accounted for in a dynamical framework, where a coherent global structure emerges through locally guided self-organization.