Transthyretin influences spatial reference memory

Transthyretin (TTR) is a plasma and cerebrospinal fluid carrier for thyroxine and retinol, described also to sequester the amyloid beta peptide. TTR levels have been described as decreased in the cerebrospinal fluid of patients with Alzheimer's disease. In order to investigate the role of TTR in learning and memory, we studied young adult and old TTR-null 129/Sv mice for cognitive performance. In the absence of TTR, 5-month-old mice display spatial reference memory impairment when compared to age-matched wild-type mice. Interestingly, while aging in wild-type mice is associated with a worsening reference memory performance, TTR-null mice show no further impairment with increasing age. As a result, no significant differences were found in this spatial reference task in old mice. Our data show that the absence of TTR seems to accelerate the poorer cognitive performance normally associated with aging.     

Does letter position coding depend on consonant/vowel status? Evidence with the masked priming technique

Recently, a number of input coding schemes (e.g., SOLAR model, SERIOL model, open-bigram model, overlap model) have been proposed that capture the transposed-letter priming effect (i.e., faster response times for jugde-JUDGE than for jupte-JUDGE). In their current version, these coding schemes do not assume any processing differences between vowels and consonants. However, in a lexical decision task, Perea and Lupker (2004, JML; Lupker, Perea, & Davis, 2008, L&CP) reported that transposed-letter priming effects occurred for consonant transpositions but not for vowel transpositions. This finding poses a challenge for these recently proposed coding schemes. Here, we report four masked priming experiments that examine whether this consonant/vowel dissociation in transposed-letter priming is task-specific. In Experiment 1, we used a lexical decision task and found a transposed-letter priming effect only for consonant transpositions. In Experiments 2-4, we employed a same-different task - a task which taps early perceptual processes - and found a robust transposed-letter priming effect that did not interact with consonant/vowel status. We examine the implications of these findings for the front-end of the models of visual word recognition.     

From the Historical Reformation to the “Digital Reformation”

This article analyzes the challenges presented for contemporary theological thinking by the current shifts in communication, starting from the concept of a “digital reformation” as a counterpart to the theological revolution that occurred with the historical Reformation. It goes on to consider how processes of communication on the Internet require us to rethink certain theological categories – from the new and renewed ways of constituting and manifesting theological knowledge within the digital environment through the emergence of new loci, subjects, and theological syntheses. We conclude that the challenges of contemporary digital culture and the need for a connected theology mean that theology, as a field of knowledge, requires a new theological synthesis.     

Studying psychotherapy change in narrative terms: The innovative moments method

This paper aims to describe the Innovative Moments (IM) Coding System (IMCS), an idiographic and transtheoretical methodology that allows the identification of IMs—markers of changes in the client's initial maladaptive framework of meaning—throughout psychotherapy. The present study introduces the theoretical background underlying this methodology, along with the main empirical findings resulting from former studies that have applied this tool to clinical data. The IMCS application is also detailed: the coding phases, the training steps and inter‐rater agreement measures. In order to illustrate the application of IM coding, a case study is presented. Although a partial coding was used, the results are in line with previous research. Discussion is centred on the usefulness of the IMCS for the advance of process research in psychotherapy, and the potential use of this methodology in group format.     

Child-rearing expectations and developmental knowledge according to maternal age and parity

A convenience sample of 6% mothers was surveyed according to their attitudes toward childrearing and knowledge of developmental milestones. A majority of mothers, regardless of age, were incorrect in their assessment of when key infant abilities occur. When the responses were analyzed according to age, the youngest group of mothers (16 years and less) were least knowledgeable and had the least desirable child-rearing attitudes of the three age groups, although these differences were no more than would be expected by chance alone. Parity (operationalized as no child versus at least one child) had few associations with maternal knowledge or attitudes within any of the three age groups analyzed. The results are discussed in terms of future research as well as in the context of the ongoing expansion of parenting programs for mothers and fathers of all ages.     

Problem and program linkage: The early and periodic screening,diagnosis and treatment program as a means of preventing and detecting child abuse

This paper presents a case model for linkage of social service delivery programs with the prevention and detection of child abuse. The example of problem and problem linkage is given for the Early and Periodic Screening, Diagnosis and Treatment Program (EPSDT), the nation's largest preventive child health screening program designed to detect and treat early childhood medical and developmental conditions in indigent children. The screening activities combined with the efforts to educate parents as to the nature of normal child development suggests that the EPSDT program may be used to prevent the development of conditions that may lead to abuse as well as to identify children who have been abused.     

Reviews: Books and Films

TO REDEEM ONE PERSON IS TO REDEEM THE WORLD: THE LIFE OF FRIEDA FROMM-REICHMANN. By Gail A. Hornstein. 390 pp. New York: The Free Press, 2000. $35. THE GUIDE TO PASTORAL COUNSELING AND CARE. Edited by Gary Ahlskog and Harry Sands. 415 pp. Madison, CT: International Universities Press and Psychosocial Press, 2000. $60. THE ART OF DYING: A JUNGIAN VIEW OF PATIENTS' DRAWINGS. By Yvonne Barnhouse Williams. 209 pp. Springfield, IL: Charles C. Thomas, 1999. $24.95. LITTLE SAINT. By Hannah Green. New York: Random House, 2000. $25.95. BODY AND SOUL: HUMAN NATURE AND THE CRISIS IN ETHICS. By J.P. Moreland and Scott B. Rae. 350 pp. InterVarsity Press, 2000. $22.99. MUHAMMAD AND THE RISE OF ISLAM: THE CREATION OF GROUP IDENTITY. By Subhash C. Inamdar, M.D. 266 pp. Madison, Ct: International Universities Press and Psychosocial Press, 2001. $40. MANAGING MANAGED CARE: SECRETS FROM A FORMER CASE MANAGER. By Susan Frager. 276 pp. New York: John Wiley and Sons, 2000. $45. THE DISABLED GOD: TOWARD A LIBERATORY THEOLOGY OF DISABILITY. By Nancy L. Eiesland. 139 pp. Nashville: Abingdon Press, 1994. $15. A LIFE COMPLETE. By Sallierae Henderson. 222 pp. New York: Scribner, 2000. $24. BIOENGAGEMENT: MAKING A CHRISTIAN DIFFERENCE IN BIOETHICS TODAY. Edited by Nigel Cameron, Scott Daniel and Barbara White. 265 pp. Grand Rapids, MI: Wm.B.Eerdmans, 2000. $22. CALLED INTO HEALING: RECLAIMING OUR JUDEO-CHRISTIAN LEGACY OF HEALING TOUCH. By Linda L. Smith. 244 pp. Arvada, CO: HTSM Press, 2000. $22.95. SURVEYING THE RELIGIOUS LANDSCAPE: TRENDS IN U.S. BELIEFS. By George Gallup, Jr. and D. Michael Lindsay. 171 pp. Harrisburg, PA: Morehouse Publishing, 1999. $17.95. The Straight Story. Snow Falling On Cedars     

SYLLABARIUM: An online application for deriving complete statistics for Basque and Spanish orthographic syllables

The present article introduces SYLLABARIUM, a new Web tool addressing the needs of linguists, psycholinguists, and cognitive scientists who work with Spanish and/or Basque and are interested in retrieving information about several syllable-related parameters. This new online syllabic database allows the user to generate complete lists of Spanish and Basque syllables with information about the syllable frequency. Among other measures, for a given orthographic syllable, SYLLABARIUM provides its number of occurrences (i.e., the type frequency), the summed lexical frequency of the words that contain this syllable (i.e., the token frequency), and the positional distribution of type and token frequencies. The cross-language feature of SYLLABARIUM is of special interest to researchers aiming to explore the influence of the syllable in bilingualism. The Web tool is available at www.bcbl.eu/syllabarium.