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Genetic Cancer Risk Assessment and Counseling: Recommendations of the National Society of Genetic Counselors 总被引:4,自引:0,他引:4
Trepanier A Ahrens M McKinnon W Peters J Stopfer J Grumet SC Manley S Culver JO Acton R Larsen-Haidle J Correia LA Bennett R Pettersen B Ferlita TD Costalas JW Hunt K Donlon S Skrzynia C Farrell C Callif-Daley F Vockley CW;National Society of Genetic Counselors 《Journal of genetic counseling》2004,13(2):83-114
These cancer genetic counseling recommendations describe the medical, psychosocial, and ethical ramifications of identifying at-risk individuals through cancer risk assessment with or without genetic testing. They were developed by members of the Practice Issues Subcommittee of the National Society of Genetic Counselors Cancer Genetic Counseling Special Interest Group. The information contained in this document is derived from extensive review of the current literature on cancer genetic risk assessment and counseling as well as the personal expertise of genetic counselors specializing in cancer genetics. The recommendations are intended to provide information about the process of genetic counseling and risk assessment for hereditary cancer disorders rather than specific information about individual syndromes. Key components include the intake (medical and family histories), psychosocial assessment (assessment of risk perception), cancer risk assessment (determination and communication of risk), molecular testing for hereditary cancer syndromes (regulations, informed consent, and counseling process), and follow-up considerations. These recommendations should not be construed as dictating an exclusive course of management, nor does use of such recommendations guarantee a particular outcome. These recommendations do not displace a health care provider's professional judgment based on the clinical circumstances of a client. 相似文献
94.
Four monkeys and 6 humans representing five different native languages were compared in the ability to categorize natural CV tokens of /b/ versus /d/ produced by 4 talkers of American English (2 male, 2 female) in four vowel contexts (/i, e, a, u/). A two-choice "left/right" procedure was used in which both percentage correct and response time data were compared between species. Both measures indicated striking context effects for monkeys, in that they performed better for the back vowels /a/ and /u/ than for the front vowels /i/ and /e/. Humans showed no context effects for the percentage correct measure, but their response times showed an enhancement for the /i/ vowel, in contrast with monkeys. Results suggest that monkey perception of place of articulation is more dependent than human perception on the direction of the F2 onset transitions of syllables, since back-vowel F2s differentiate /b/ and /d/ more distinctively. Although monkeys do not provide an accurate model of the adult human in place perception, they may be able to model the preverbal human infant before it learns a more speech-specific strategy of place information extraction. 相似文献
95.
Memory &; Cognition - Co-reference occurs when two or more noun phrases refer to the same individual, as in the following inferential problem: Mark is kneeling by the fire or he is looking at... 相似文献
96.
Two studies of the clinical work of experienced psychoanalysts are presented. Study I is a retrospective study of all the analytic work--161 cases--of sixteen analysts from 1973 to 1977, including their evaluations of the treatments at outcome. Study II is a prospective study of the ninety-two cases started in analysis by a group of twenty analysts between 1984 and 1989 and followed to termination, including their reports. The history of each treatment as reported and evaluated by the analyst is examined in terms of: nature of the population, the analyst's view of the case when the initial recommendation was made, duration of treatment, therapeutic benefit, rating of analyzability at termination of treatment, nature of the termination, and cases changed to psychotherapy. Some old shibboleths are challenged as perspective on both the limitations and achievements of psychoanalysis emerges from the findings of the study. 相似文献
97.
Walsh V 《Trends in cognitive sciences》2003,7(11):483-488
Research into the perception of space, time and quantity has generated three separate literatures. That number can be represented spatially is, of course, well accepted and forms a basis for research into spatial aspects of numerical processing. Links between number and time or between space and time, on the other hand, are rarely discussed and the shared properties of all three systems have not been considered. I propose here that time, space and quantity are part of a generalized magnitude system. I outline A Theory Of Magnitude (ATOM) as a conceptually new framework within which to re-interpret the cortical processing of these elements of the environment. 相似文献
98.
Ronald L. Bloom Lawrence H. Pick Joan C. Borod Kashemi D. Rorie Fani Andelman Loraine K. Obler Martin Sliwinski Alfonso L. Campbell James R. Tweedy Joan Welkowitz 《Brain and language》1999,68(3):553-565
This study examined the psychometric aspects of a verbal pragmatic rating scale. The scale contained six pragmatic features (i.e., Conciseness, Lexical Selection, Quantity, Relevancy, Specificity, and Topic Maintenance) based on Grice's cooperative principles. Fifteen right brain-damaged (RBD), 15 left brain-damaged (LBD), and 16 healthy normal control (NC) right-handed adult participants produced narratives while recollecting emotional and nonemotional experiences. Naive raters evaluated each pragmatic feature for appropriateness on a 5-point Likert scale. When reliability was examined, the overall internal consistency of the pragmatic scale was extremely high (alpha =.96). Factor analysis was conducted to examine the theoretical relations among the six pragmatic features. Three meaningful factors involving discourse content, conceptual unity, and parsimony were identified. Findings are discussed in light of Grice's model and the construct validity of the scale. 相似文献
99.
Jean F. Ayers Evangeline A. Wheeler Maria P. Fracasso M. Paz Galupo Joan S. Rabin Barbara R. Slater 《Journal of Adult Development》1999,6(3):163-173
University reform encompasses an increased emphasis on the social and emotional development of students. In particular, the development of caring, empathy, and community are emphasized. This team of psychology professors approaches the task of university reform by presenting both its philosophy of diversity inclusion and specific inclusion strategies as means of promoting enhanced development of our students. Although the discipline of psychology is used as an example, the philosophical argument and the strategic approaches may be applied to other disciplines. 相似文献
100.
Damian M. Stanley Jennifer CummingMartyn Standage Joan L. Duda 《Psychology of sport and exercise》2012,13(2):133-141