Empirical Research on Ethical Issues in Pediatric Research

Although there is usually agreement about the ethical principles that should govern research on children, there may be little agreement on how those principles should be interpreted into research procedures in some instances. Empirical research on ethical issues that arise in research on children can often elucidate ways to improve on existing research practices and ways to resolve debates about best practices. Following in the success of evidence-based medicine, evidence-based ethical problem solving in human research can enable investigators to avoid such poor alternatives as doing nothing, endlessly debating, or acting on the basis of hunch or time-honored but dubious research practices. A variety of approaches to evidence-based ethical problem solving are illustrated in this article.     

Self-implication and heart rate variability during simulated exposure to flight-related stimuli

In the present study, the relationship between self-implication during simulated exposure to feared stimuli and Heart Rate Variability (HRV) was explored within the framework of the dynamical systems model of emotion regulation proposed by Thayer and Lane (Thayer, J.F., and Lane, R.D. (2000). A model of neurovisceral integration in emotion regulation and dysregulation. Journal of Affective Disorders, 61, 201–216.). An analogue sample of flight phobics (n=15) and a matched non-phobic control group (n=15) were presented with flight-related pictures, flight-related sounds or flight-related pictures and sounds. Significant differences on self-implication during exposure to flight-related sounds were found between low and high HRV fearful flyers, the former being more self-implied. However, the expected HRV decreases in the phobic participants exposed to feared stimuli were not found. These results emphasize the need to distinguish between high and low HRV fearful flyers in order to make a better use of the simulated exposure treatments.     

Daily fluctuations in the affective states of dancers: A cross-situational test of basic needs theory

ObjectivesThis study tested the generalizability of basic needs theory (BNT; Deci & Ryan, 2000) across situations in which dancers learn and perform within vocational dance. Specifically, we examined the inter-relationships between daily and typical perceptions of autonomy support, basic psychological need satisfaction, and changes in affective states, across dance situations that were divergent in their learning and evaluative potential (dance classes, rehearsals, and performances). Genre differences were also examined.DesignA one-month diary study examined the inter-relationships between typical and daily perceptions of autonomy support, basic psychological need satisfaction and positive and negative affect among dancers studying three distinct genres and in three situations (classes, rehearsals, performances).MethodFifty-five dancers completed a series of scales tapping the variables of interest. Abbreviated versions of the scales were completed before (affective states) and after (affective states, basic needs and autonomy support) dance classes, rehearsals and performances over four weeks. Analyzes tested the BNT sequence across the learning and performance situations. Interactions between typical and state experiences were tested. Cross-genre comparisons were also made.ResultsResults partially supported the BNT sequence across classes, rehearsals and performances. There were situational differences in the salience of each need as a predictor of affective states. When comparing genres, some differences were also found in perceived autonomy support, basic need satisfaction and affective states.ConclusionsFindings point to the importance of promoting autonomy supportive dance teaching to facilitate dancers' day-to-day experiences of well-being.     

The Influence of Authoritative Parenting During Adolescence on Depressive Symptoms in Young Adulthood: Examining the Mediating Roles of Self-Development and Peer Support

A diverse sample of 1,143 high school seniors and 182 students who were part of the same cohort but who left high school without graduating were interviewed during late adolescence (Time 1 [T1]) as well as 2 (Time 2 [T2]) and 4 years later (Time 3 [T3]). Perceived self-development, peer support, and prior levels of depressive symptoms (T2) were hypothesized to mediate the relationship between authoritative parenting during adolescence (T1) and depressive symptoms during young adulthood (T3). T2 sense of self as worthy and efficacious and depressive symptoms, but not peer support, fully mediated the effect of authoritative parenting on T3 depressive symptoms. The authors discuss the importance of parenting for healthy, emerging adult self-development and the continuing influence of parenting styles during adolescence on young adult depressive symptoms.     

The Nature of the Co-Therapy Relationship

Termination is a complex phase in the total therapeutic process. Criteria for termination of long-term analytic group therapy encompass both intrapsychic and behavioral changes. One of the useful ways of conceptualizing the termination phase is in terms of the issues of separation-individuation. Three different kinds of termination that can occur and the techniques for working with each are described. Multiple transferences are worked with in the long-term analytic group and both real and transferential losses acknowledged. The ability to leave group therapy with a stronger, better defined sense of self is one of the goals of therapy.     

Distinguishing youths at risk for anxiety disorders from self‐reported BIS sensitivity and its psychophysiological concomitants

The aim of the study was to explore the psychophysiological concomitants of self‐reported behavioral inhibition system (BIS) sensitivity in adolescents (12 to 17 years old) supposed to be at risk for anxiety disorders. Twenty participants with high scores in self‐reported BIS sensitivity (at‐risk group) were matched in age and sex to 20 participants scoring in the normal range in BIS sensitivity (control group). Negative affect, negative emotion regulation style, and anxiety symptomatology were assessed by means of self‐reported measures. Cardiac and electrodermal response signals were recorded during baseline, paced breathing, exposure to an attentional task with response cost and fear‐relevant slides conditions. The at‐risk group exhibited higher scores on measures of negative affect, negative emotion regulation style, and anxiety symptomatology than their control counterparts. After controlling for negative styles of emotion regulation, groups did not differ in skin conductance reactivity during the attentional task with response cost, but participants at risk exhibited more nonspecific skin conductance responses than the control group during baseline recording. Regarding the cardiac concomitants, participants at risk presented lower vagal tone at resting conditions as compared to participants in the control group. Additionally, at‐risk participants exhibited lower flexibility across experimental conditions in heart rate and cardiac sample entropy measures than participants in the control group. These findings add knowledge on psychophysiological concomitants of BIS sensitivity and are discussed in light of associations between temperament and development of anxiety disorders in youth. They show how psychophysiological patterns observed in resting conditions could be useful endophenotypes to reliably detect individuals at risk before the disorder onset.     

God,Truth and Mathematics in Nineteenth-century England

In his Essay Concerning Human Understanding, John Locke created a special epistemological category for mathematical and religious knowing. This category of knowledge was quickly brushed to the side in the French Enlightenment, but the English preserved it well into the nineteenth century. This article considers the ways that the neo-Lockian joining of mathematics and theology fundamentally affected both mathematical and theological thinking in the first half of the English nineteenth century. It argues that these developments set the stage for the post-Darwinian conflicts between science—including mathematics—and religion.     

Naturalistic Experience and the Early Use of Symbolic Artifacts

Experience with a variety of symbolic artifacts has been proposed as a mechanism underlying symbolic development. In this study, the parents of 120 2-year-old children who participated in symbolic object retrieval tasks completed a questionnaire regarding their children's naturalistic experience with symbolic artifacts and activities. In separate regressions predicting children's use of video and pictures for information in experimental tasks, predictor variables such as children's exposure to live video and their emerging understanding of graphic representation were significant, even after accounting for the effects of children's vocabulary and birth order and parents' education and occupation. The results support the role of experience in children's early detection of symbolic relations.     

Functional brain activation to emotional and nonemotional faces in healthy children: Evidence for developmentally undifferentiated amygdala function during the school-age period

The amygdala is a key region in emotion processing. In particular, fMRI studies have demonstrated that the amygdala is active during the viewing of emotional faces. Previous research has consistently found greater amygdala responses to fearful than to neutral faces in adults, convergent with a focus in the animal literature on the amygdala’s role in fear processing. Studies have shown that the amygdala also responds differentially to other facial emotion types in adults. Yet the literature regarding when this differential amygdala responsivity develops is limited and mixed. Thus, the goal of the present study was to examine amygdala responses to emotional and neutral faces in a relatively large sample of healthy school-age children (N?=?52). Although the amygdala was active in response to emotional and neutral faces, the results did not support the hypothesis that the amygdala responds differentially to emotional faces in 7- to 12-year-old children. Nonetheless, amygdala activity was correlated with the severity of subclinical depression symptoms and with emotional regulation skills. Additionally, sex differences were observed in frontal, temporal, and visual regions, as well as effects of pubertal development in visual regions. These findings suggest important differences in amygdala reactivity in childhood.     

Suffering by comparison: Twitter users’ reactions to the Victoria's Secret Fashion Show

Social comparison theory suggests that evaluating the self in comparison with others (e.g., peers, celebrities, models) can influence body image. Experimental studies that have tested effects of viewing idealized images in the media often show that women feel worse about themselves after seeing images that illustrate the beauty ideal. Twitter presents a naturally occurring opportunity to study viewers’ reactions. An analysis was conducted of 977 tweets sent immediately before and during the 2011 Victoria's Secret Fashion Show that reference the show. Although the majority were idiosyncratic remarks, many tweets contain evidence of upward social comparisons to the fashion models. There were tweets about body image, eating disorders, weight, desires for food or alcohol, and thoughts about self-harm. The results support social comparison theory, and suggest that vulnerable viewers could experience negative affect, or even engage in harmful behaviors, during or after viewing the show or others like it.