论自主性与公正之间的张力--一试管受精案例引起的伦理困境

高科技医疗技术,如试管受精技术在医疗实践中往往引发伦理原则之间的冲突.通过对英国一试管受精案例的分析,展示自主性原则与公正原则之间存在的深层张力.在对两个基本范畴作哲学解析的基础上,寻找两个基本原则的契合点,为解决类似的伦理困境提供一奈可能的途径.     

Trusting in others’ biases: Fostering guarded trust in collaborative filtering and recommender systems

Collaborative filtering is being used within organizations and in community contexts for knowledge management and decision support as well as the facilitation of interactions among individuals. This article analyzes rhetorical and technical efforts to establish trust in the constructions of individual opinions, reputations, and tastes provided by these systems. These initiatives have some important parallels with early efforts to support quantitative opinion polling and construct the notion of “public opinion.” The article explores specific ways to increase trust in these systems, albeit a “guarded trust” in which individuals actively seek information about system foibles and analyze the reputations of participants. She received her MBA, MA, MS, and Ph.D. degrees from the University of Wisconsin at Madison. She taught computer information systems and public policy at Baruch College of the City University of New York and also taught in the School of Business and the Computer Sciences Department at UW-Madison. In the 1990s, she served as the chair of the Privacy Council of the State of Wisconsin, the nation’s first state-level council dealing with information technology and privacy issues. She has written several books (including Virtual Individuals, Virtual Groups: Human Dimensions of Groupware and Computer Networking, Cambridge University Press and Home as Information Space: Electronic Commerce and the Domestication of Computer Networking, forthcoming). She has worked for public television and developed software along with her academic ventures.     

Black and white fire: the interplay of stories,imagination and children's spirituality

This paper explores the potential for using narrative to foster children's spiritual growth. It discusses the nature, origin and appeal of story and presents theoretical perspectives which form a rationale for using non‐sectarian children's, adolescent and young adult literature for spiritual development. Such books avoid church‐and‐state controversies while providing a fresh approach to educators where religious and spiritual education are mandated.     

Appetitive instrumental learning is impaired by inhibition of cAMP-dependent protein kinase within the nucleus accumbens.

The medium spiny neurons of the nucleus accumbens receive a unique convergence of dopaminergic and glutamatergic inputs from regions associated with motivational, cognitive, and sensory processes. Long-term forms of plasticity in the nucleus accumbens associated with such processes as appetitive learning and drug addiction may require coactivation of both dopamine D1 and glutamate N-methyl-D-aspartate (NMDA) receptors. This notion implies that an intracellular mechanism is likely to be involved in these long-term neuroadaptive processes. The present series of experiments examined the effects of intra-accumbens microinfusion of protein kinase inhibitors on acquisition of an instrumental task, lever-pressing for food. Male Sprague-Dawley rats were bilaterally implanted with chronic indwelling cannulae aimed at the nucleus accumbens core. Following recovery, animals were food-restricted and subsequently trained for operant responding. The broad-based serine/threonine kinase inhibitor H-7 (5 or 27 nmol per side) dose-dependently impaired learning when infused immediately after testing on days 1-4. Rp-cAMPS, a cAMP-dependent protein kinase (PKA) inhibitor, also impaired learning regardless of whether it was infused immediately before (5 or 20 nmol) or immediately after (10 nmol) testing on days 1-4. Rp-cAMPS (10 nmol) also inhibited learning when infused 1 h after testing, though to a lesser extent than when administered before or immediately after testing. The PKA stimulator Sp-cAMPS (5 or 20 nmol) also impaired learning when infused before testing, suggesting that there is an optimal level of PKA activity required for learning. None of the drugs used produced nonspecific motor or feeding effects. These results provide evidence supporting the involvement of nucleus accumbens PKA in appetitive learning and suggest that this kinase may be involved in long-term changes associated with this and other motivationally based neuroadaptive processes.     

A Topological Model of Epistemic Intentionality

Beyond their linguistic and rhetorical uses, the mental epistemic verbs to knowand to believe reveal a basic conceptual system for human intentionality and the theory of representational mind. Numerous studies, particularly in the field of child development, have been devoted to the conditions under which knowledge and belief are acquired. Upstream of this empirical approach, this paper proposes a topological model of the conceptual structure underlying the linguistic use of to know and to believe. A cusp model of catastrophe theory is chosen to model the formation of epistemic states. Its main characteristic is considering to believe as an intermediate state which lacks stability and presents the delayed effect of hysteresis. The attribution of mental states to the other (viewpoint of the third person) is obtained by the crossing of first and third person knowledge and belief, which gives rise to new categories (to know if and to falsely believe) and closes the system. Another merging of the beliefs of persons A and B, using the butterfly catastrophe, provides a model of interpersonal belief appreciated by an independent observer along a potential evolving from agreement to disagreement. This revised version was published online in August 2006 with corrections to the Cover Date.     

Consultant or Comrade: Comments About Analysts' Working Relationships in Schools

The articles in this issue of the Journal of Applied Psychoanalytic Studies pose a dilemma for educators. On the one hand, each article describes an important psychosocial intervention implemented in schools. On the other hand, these interventions, at least as described in the articles, are either imposed on the work of teachers and students or isolated from that work. Either circumstance ultimately limits the impact of the intervention. I claim that analysts and teachers are natural allies despite lack of evidence for alliance in these articles. To extend that alliance beyond conversations about individual children, analysts must understand that teachers' views of learning and development are different from those that influence the organization and management of schools.     

Inner-City Children Living with an HIV-Seropositive Mother: Parent–Child Relationships, Perception of Social Support, and Psychological Disturbance

Despite ongoing concern about the well-being of HIV-seronegative children living in urban poverty with a seropositive mother, very little is known about this expanding population of children. In this cross-sectional study, the psychosocial adjustment of 60 ethnic minority children 11 to 16 years of age who were living with an HIV-seropositive mother was compared with that of 108 children attending public school in the same community. Results of three multivariate analyses of covariance indicated that, after allowance for differences associated with age, gender, ethnicity, and family structure, the HIV-affected group confirmed (a) greater disturbance in the parent–child relationship, (b) less social support, and (c) greater disturbance in psychological functioning. Secondary analysis of the multivariate findings indicated that the differences were characterized primarily by (a) perception of more indifference and hostility in the mother–child relationship, (b) perception of less social support available from parents, friends, and teachers, and (c) less self-esteem. The findings suggest that HIV infection and concurrent problems may compromise parent–child relationships and perception of social support in ways that leave older, seronegative children living with an infected mother at risk for psychological disturbance.     

Gender-Linked Differences in Everyday Memory Performance: Effort Makes the Difference

Previous research has found gender differences in everyday memory tasks such as remembering shopping lists or directions, and these findings can be attributed to increased motivation or memory skill resulting from the association of different tasks with masculine or feminine gender roles. To investigate the motivational explanation, the recall of an ambiguous shopping list, labeled as grocery or hardware, was examined under instructions that stated that either women or men are good at the task, or instructions that were neutral. The findings were not consistent with the skill explanation. There was a significant interaction between list label, participant gender, and instructions, which can be explained in terms of the increased or decreased motivation that might arise from particular combinations of label and instruction.