The advantage of first mention in Spanish

An advantage of first mention—that is, faster access to participants mentioned first in a sentence—has previously been demonstrated only in English. We report three experiments demonstrating that the advantage of first mention occurs also in Spanish sentences, regardless of whether the first-mentioned participants are syntactic subjects, and regardless, too, of whether they are proper names or inanimate objects. Because greater word-order flexibility is allowed in Spanish than in English (e.g., nonpassive object-verb-subject constructions exist in Spanish), these findings provide additional evidence that the advantage of first mention is a general cognitive phenomenon.     

Compassion: An east‐west comparison

Compassion is an emotion that occupies a central position in Mahāyāna Buddhist philosophy while it is often a neglected subject in contemporary western philosophy. This essay is a comparison between an Eastern view of compassion based upon Mahāyāna Buddhist perspectives and a western view of the same emotion. Certain principles found in Mahāyāna Buddhist philosophy such as the Bodhisattva Ideal, and suffering (dukkha) to name two, are explored for the information they contain about compassion. An essay by Lawrence Blum is taken as representative of a Western view (but not exclusively) and it is analyzed for its shortcomings in light of the Buddhist view. The conclusion briefly describes the value of understanding an eastern view on compassion as a means of filling the void one finds in western medical ethics discourse which focuses so heavily, and redundantly, upon issues such as patient autonomy and paternalism.     

THE UNIT PLAY MANAGER AS FACILITATOR OF PURPOSEFUL ACTIVITIES AMONG INSTITUTIONALIZED PROFOUNDLY AND SEVERELY RETARDED BOYS

Child care workers were trained in specified techniques (play manager routines) in an effort to increase purposeful activity among a group of profoundly and severely retarded institutionalized boys. A system of prompts, increasing the availability of toys and regular staff monitoring, were alternated with normal institutional routines in an ABA reversal design. On the average, activity level increased from 10% to a mean of 70% during treatment conditions. Correspondingly, stereotyped or harmful behaviors decreased from an average of 20% to 70% during treatment.     

Something from nothing: exploring dimensions of children's knowing through the repeated reading of favourite books

Witte‐Townsend and DiGiulio explore some of the dimensions of knowing that children, teachers and parents may engage together during story‐time. They reflect on some of their own long‐term relationships with children and children's books, especially Phoebe Gilman's Gilman P 1992 Something from nothing (New York, NY, Scholastic Inc)  [Google Scholar] Something from nothing (published in 1992) and Simms Taback's Taback S 1999 Joseph had a little overcoat (New York, NY, Viking‐Penguin)  [Google Scholar] Joseph had a little overcoat, published in 1999. The authors probe issues such as why children ask to hear a favourite story over and over and why they suddenly abandon all interest and move on to a new book. They explore the meaning of the silences that sometimes arise during story‐time, pooling around the young listeners as the last words of the book are read. Witte‐Townsend and DiGiulio remind us of the value of literature in the lives of children and they affirm that the reading and re‐reading of favourite stories enables the understanding of complex human issues and contributes significantly to social, emotional and spiritual growth.     

Unaltered ethical standards for individual physicians in the face of drastically reduced resources resulting from an improvised nuclear device event

When disaster disrupts healthcare and other systems, the ethical allocation of resources should follow principles of justice, defined as fairness, established for normal clinical practice. Standards of clinical practice may be altered during disaster, but ethical standards must remain centered on prioritizing the treatment of patients according to need and the effectiveness of treatment. Should resources become extremely limited, it is fair to restrict their use to patients who have the highest needs, provided that the intervention is effective. When resources become more available, patients with lower priority can be increasingly accommodated.     

Hippocampal tauopathy in tau transgenic mice coincides with impaired hippocampus-dependent learning and memory, and attenuated late-phase long-term depression of synaptic transmission

We evaluated various forms of hippocampus-dependent learning and memory, and hippocampal synaptic plasticity in THY-Tau22 transgenic mice, a murine tauopathy model that expresses double-mutated 4-repeat human tau, and shows neuropathological tau hyperphosphorylation and aggregation throughout the brain. Focussing on hippocampus, immunohistochemical studies in aged THY-Tau22 mice revealed prominent hyper- and abnormal phosphorylation of tau in CA1 region, and an increase in glial fibrillary acidic protein (GFAP) in hippocampus, but without signs of neuronal loss. These mice displayed spatial, social, and contextual learning and memory defects that could not be reduced to subtle neuromotor disability. The behavioral defects coincided with changes in hippocampal synaptic functioning and plasticity as measured in paired-pulse and novel long-term depression protocols. These results indicate that hippocampal tauopathy without neuronal cell loss can impair neural and behavioral plasticity, and further show that transgenic mice, such as the THY-Tau22 strain, might be useful for preclinical research on tauopathy pathogenesis and possible treatment.     

Ethics in 15 min per Week

The demand for science trainees to have appropriate responsible conduct of research instruction continues to increase the attention shown by federal agencies and graduate school programs to the development of effective ethics curriculums. However, it is important to consider that the main learning environment for science graduate students and post-doctoral research fellows is within a laboratory setting. Here we discuss an internal laboratory program of weekly 15-minute ethics discussions implemented and used over the last 3 years in addition to the graduate school’s program of scientific integrity training. During this time, the environment and culture within our laboratory has changed to place greater emphasis on the ethical implications of our own research and the research we evaluate. We still struggle with how to accurately assess this behavioral change; although, we present preliminary survey results on the evaluation and impact of this style of curriculum for ethics instruction in our laboratory.     

What coping tells about personality

In this study, 123 participants (non‐psychology students) who responded to an interpersonal stress situation staged in the laboratory were judged by unacquainted observers in terms of the Big Five dimensions, intelligence and social attractiveness. Coping behaviour appeared to predict personality impressions in a way that mirrors the relations between personality and coping observed in previous research: Overall, higher levels of Extraversion (E), Agreeableness (A), Conscientiousness (C) and Openness to experience (O) (as well as intelligence and social attractiveness) were predicted by problem‐focussed behaviour and cognitive restructuring, whereas higher levels of Neuroticism (N) were predicted by withdrawal/passivity. The interpersonal impact of the particular coping reactions, as indicated by a positive personality impression, were largely inconsistent with their impact on affect following the stress induction. Copyright © 2009 John Wiley & Sons, Ltd.     

Preparing for Year 12 examinations: Predictors of psychological distress and sleep

This study examined the influence of protective factors on psychological distress and sleep among Year 12 students 1 month prior to their externally assessed examinations. The sample included 195 Year 12 students who were to sit for at least one examination. Students completed the Adolescent Resilience Questionnaire, a measure of subjective stress, the Depression Anxiety and Stress Scales – 21, and measures of sleep. A sizeable minority of students reported high levels of subjective stress, severe symptoms of depression, anxiety and stress, and very inadequate sleep. Freedom from negative cognitions was the factor most strongly associated with protection from psychological distress. None of the factors protected against inadequate sleep. Results showed few gender differences. The findings validate popular concern about the wellbeing of Year 12 students. They also confirm that protective factors do not provide equal protection for all individuals against all adverse outcomes.