Exposure to severe urban air pollution influences cognitive outcomes, brain volume and systemic inflammation in clinically healthy children

Exposure to severe air pollution produces neuroinflammation and structural brain alterations in children. We tested whether patterns of brain growth, cognitive deficits and white matter hyperintensities (WMH) are associated with exposures to severe air pollution. Baseline and 1 year follow-up measurements of global and regional brain MRI volumes, cognitive abilities (Wechsler Intelligence Scale for Children-Revised, WISC-R), and serum inflammatory mediators were collected in 20 Mexico City (MC) children (10 with white matter hyperintensities, WMH⁺, and 10 without, WMH⁻) and 10 matched controls (CTL) from a low polluted city. There were significant differences in white matter volumes between CTL and MC children - both WMH⁺ and WMH⁻ - in right parietal and bilateral temporal areas. Both WMH⁻ and WMH⁺ MC children showed progressive deficits, compared to CTL children, on the WISC-R Vocabulary and Digit Span subtests. The cognitive deficits in highly exposed children match the localization of the volumetric differences detected over the 1 year follow-up, since the deficits observed are consistent with impairment of parietal and temporal lobe functions. Regardless of the presence of prefrontal WMH, Mexico City children performed more poorly across a variety of cognitive tests, compared to CTL children, thus WMH⁺ is likely only partially identifying underlying white matter pathology. Together these findings reveal that exposure to air pollution may perturb the trajectory of cerebral development and result in cognitive deficits during childhood.     

Effects of training condition on the contribution of specific items to relational processing in baboons (Papio papio)

Relational processing involves learning about the relationship between or among stimuli, transcending the individual stimuli, so that abstract knowledge generalizable to novel situations is acquired. Relational processing has been studied in animals as well as in humans, but little attention has been paid to the contribution of specific items to relational thinking or to the factors that may affect that contribution. This study assessed the intertwined effects of item and relational processing in nonhuman primates. Using a procedure that entailed both expanding and contracting sets of pictorial items, we trained 13 baboons on a two-alternative forced-choice task, in which they had to distinguish horizontal from vertical relational patterns. In Experiment 1, monkeys engaged in item-based processing with a small training set size, and they progressively engaged in relation-based processing as training set size was increased. However, in Experiment 2, overtraining with a small stimulus set promoted the processing of item-based information. These findings underscore similarities in how humans and nonhuman primates process higher-order stimulus relations.     

Spirituality in Occupational Therapy: Do We Practice What We Teach?

This mixed-method study examined the responses of 97 occupational therapists on the subject of spirituality in occupational therapy practice. The inclusion of spirituality into the Occupational Therapy Practice Framework (2008) implies that clinicians address spirituality as a component of client-centered practice. This research revealed a gap between education, theory, and practice as evidenced in the quantitative and qualitative data. Although occupational therapy is intended to be holistic, therapists require a more complete understanding of what spirituality is and what the role of the occupational therapist is when addressing spirituality in evaluation or treatment. The discussion of this research provides information for future occupational therapy educators and educational programs as they seek to incorporate the construct of spirituality into curricula.     

Religious Beliefs or Physicians’ Behavior: What Makes a Patient More Prone to Accept a Physician to Address His/Her Spiritual Issues?

The present study aims to understand the relation between religious beliefs, physicians’ behavior and patients’ opinions regarding “Spirituality, religiosity and health (S/R)” issues, and what makes a patient more prone to accept a physician to address his/her spiritual issues. A cross-sectional study was carried out in outpatients from a tertiary hospital, and a path analysis was used to examine the direct and indirect relationships between the variables. For the final analysis, 300 outpatients were evaluated. Most patients would like their doctors to address S/R issues but did not feel comfortable to ask them. In contrast, they reported most doctors have never addressed S/R issues, and they believe doctors are not prepared to address these issues. The path analysis revealed that patients’ previous experiences with their doctors may be as important as their religious/spiritual beliefs in proneness to accept a physician to address his/her spiritual issues.     

Effect on Comprehension of Preposed versus Postposed Adverbial Phrases

A challenge for psycholinguistics is to describe how linguistic cues influence the construction of the mental representation resulting from the comprehension of a text. In this paper, we will focus on one of these linguistic devices: the sentence-initial positioning of spatial adverbials such as In the park.... Three self-paced reading experiments were conducted to test the ‘Discourse Framing Hypothesis’ according to which preposed adverbials can be seen as frame builders announcing that incoming contents satisfy the same informational criterion specified by the adverbial. Our results indicate that spatial adverbials do not play the same role when they are in sentence-initial and in sentence-final position. These results are discussed in the framework of Zwaan’s Event Indexing Model.     

Assessment of cognitive function across pregnancy using CANTAB: A longitudinal study

Significant changes in endogenous plasma hormone levels are required to sustain pregnancy which provides a unique opportunity to study their effect on cognitive function.     

Shyness and Psychosocial Functioning in South Korean Children

The purpose of this study was to examine whether anxious shyness and regulated shyness, initially identified in the Chinese culture, is found in South Korean children, and to explore whether these two forms of shyness were differentially related to children's psychosocial functioning. Participants were 544 fourth to sixth grade children (251 girls, M age = 11.38 years old) who were recruited from an elementary school in Bucheon City, South Korea. Children's anxious and regulated shyness were measured using peers' nominations and teachers' ratings, whereas their social preference and social impact were assessed using peers' nominations. Parents rated their children's temperamental shyness and effortful control, and children self‐reported their loneliness and interpersonal concerns. The results of confirmatory factor analysis replicated the two factor model of shyness found in previous studies of Chinese children. Anxious shyness and regulated shyness were positively associated and were similarly related to temperamental shyness. Anxious shyness was negatively related to effortful control and social preference, and positively associated with self‐reported loneliness and interpersonal concerns, whereas regulated shyness was positively related to effortful control and social preference and negatively associated with loneliness and social impact. These results were generally consistent with prior Chinese findings and provided preliminary support for the construct validity of anxious and regulated shyness in another Asian culture that emphasizes interdependence and modesty. Copyright © 2013 John Wiley & Sons, Ltd.     

Drop the Small Talk When Establishing Baseline Behaviour in Interviews

The present experiment investigated the behavioural patterns of interviewees when comparing their baseline behaviour, prior to the interview, with their behaviour during the investigative interview. Similar to what has been advised in the police literature, the truthful baseline behaviour was established prior to the interview through non‐threatening questions. The investigative part of the interview then followed in which the interviewee was aware that they would be assessed on whether they were lying. During the investigative part, interviewees either discussed the job that they had (truth tellers, n = 128) or pretended to have (liars, n = 115). Findings revealed that both liars and truth tellers' behavioural patterns differed between the baseline behaviour and the investigative part of the interview. The findings suggest small talk should not be used as a baseline comparison with the investigative part of the interview when determining if the interviewee is being deceitful. An alternative way of using a baseline lie detection method, the comparable truth method, is discussed. Copyright © 2014 John Wiley & Sons, Ltd.     

Family conflict is associated with longitudinal changes in insular‐striatal functional connectivity during adolescent risk taking under maternal influence

Maternal presence has marked effects on adolescent neurocognition during risk taking, influencing teenagers to make safer decisions. However, it is currently unknown whether maternal buffering changes over the course of adolescence itself, and whether its effects are robust to individual differences in family relationship quality. In the current longitudinal study, 23 adolescents completed a risk‐taking task under maternal presence during an fMRI scan before and after the transition to high school. Behavioral results reveal that adolescent risk taking increased under maternal presence across a one‐year period. At the neural level, we found that adolescents reporting higher family conflict showed longitudinal increases in functional coupling between the anterior insula (AI) and ventral striatum (VS) when making safe decisions in the presence of their mother, which was associated with increased real‐world risk taking. These findings show that individual differences in family relationship quality undermine effective development of AI‐VS connectivity resulting in increased risk taking.     

Mother still knows best: Maternal influence uniquely modulates adolescent reward sensitivity during risk taking

Adolescent decision‐making is highly sensitive to input from the social environment. In particular, adult and maternal presence influence adolescents to make safer decisions when encountered with risky scenarios. However, it is currently unknown whether maternal presence confers a greater advantage than mere adult presence in buffering adolescent risk taking. In the current study, 23 adolescents completed a risk‐taking task during an fMRI scan in the presence of their mother and an unknown adult. Results reveal that maternal presence elicits greater activation in reward‐related neural circuits when making safe decisions but decreased activation following risky choices. Moreover, adolescents evidenced a more immature neural phenotype when making risky choices in the presence of an adult compared to mother, as evidenced by positive functional coupling between the ventral striatum and medial prefrontal cortex. Our results underscore the importance of maternal stimuli in bolstering adolescent decision‐making in risky scenarios.