Cognitive Remediation in Schizophrenia

Cognitive deficits are routinely evident in schizophrenia, and are of sufficient magnitude to influence functional outcomes in work, social functioning and illness management. Cognitive remediation is an evidenced-based non-pharmacological treatment for the neurocognitive deficits seen in schizophrenia. Narrowly defined, cognitive remediation is a set of cognitive drills or compensatory interventions designed to enhance cognitive functioning, but from the vantage of the psychiatric rehabilitation field, cognitive remediation is a therapy which engages the patient in learning activities that enhance the neurocognitive skills relevant to their chosen recovery goals. Cognitive remediation programs vary in the extent to which they reflect these narrow or broader perspectives but six meta-analytic studies report moderate range effect sizes on cognitive test performance, and daily functioning. Reciprocal interactions between baseline ability level, the type of instructional techniques used, and motivation provide some explanatory power for the heterogeneity in patient response to cognitive remediation.     

Identity‐based motivation: Constraints and opportunities in consumer research

This commentary underscores the integrative nature of the identity-based motivation model (Oyserman, D. (2009). Identity-based motivation: Implications for action-readiness, procedural-readiness, and consumer behavior. Journal of Consumer Psychology, 19(3) (this issue)). We situate the model within existing literatures in psychology and consumer behavior, and illustrate its novel elements with research examples. Special attention is devoted to, 1) how product- and brand-based affordances constrain identity-based motivation processes and, 2) the mindsets and action tendencies that can be triggered by specific cultural identities in pursuit of consumer goals. Future opportunities are suggested for researching the antecedents of product meanings and relevant identities.     

Perceived Peer Norms,Casual Sex,and AIDS Risk Prevention1

To facilitate more effective AIDS education with heterosexual college students, an etiological study of AIDS risk behavior was conducted on a sample of 1,035 students at a large western university. In this study, “AIDS risk behavior” refers to participation in casual sex, failure to use condoms, and resistance to changing casual sex activity. Knowledge regarding AIDS had no significant correlation with AIDS-risk behavior. However, “perceived peer norms” (termed Peer Norm in this study) was a major predictor variable in AIDS risk behavior. Peer Norm was defined as perceived AIDS-risk attitudes and the behavior of one's peers. These findings contrast some what with those of Emmons et al.'s (1986) study of homosexual men. This difference may be due to the focus in the present study upon heterosexual university students as subjects. For this group, our results suggest that programs targeting the peer group in AIDS prevention education are especially needed. These might include peer-based AIDS education, emotion-oriented discussion sessions, encounters with “Peers-with-AIDS” models, and role-playing of assertive responses.     

Dropping out of parent training

The purpose of the present study was to determine the dropout rate when parents are taught to modify their children's problem behavior. Eight journals were examined for parent-training studies. Forty-five studies were found but only 22 of these reported dropout data. Studies were examined for dropout rate and in order to determine if the point in therapy at which dropout occurred was specified. The overall dropout rate was 28% and most studies specified when the dropout occurred. Finally, variables that are critical to dropping out when parent training is undertaken are presented and recommendations are made for future research.     

Naming versus matching in color constancy

In this paper, a replication of the color-constancy study of Arend and Reeves (1986) is reported, and an alternative method is presented that can be used for the study of higher order aspects of color constancy, such as memory, familiarity, and perceptual organization. Besides a simultaneous presentation of standard and test illuminants, we also carried out an experiment in which the illuminants were presented successively. The results were similar to Arend and Reeves’s; however, in the object-matching condition of the successive experiment, we found an overestimation, instead of an underestimation, of the illuminant component. Because the results of matching experiments are difficult to interpret, mainly due to their sensitivity to instruction effects, we introduced another type of color-constancy task. In this task, subjects simply named the color of a simulated patch. It was found that, by applying such a task, a reliable measure of the degree of identification of object color can be obtained.     

Adolescents’ Faith Commitments as Correlates of Their Involvement in Christian Service

This study sought to determine the relationship between adolescents’ involvement in service to others and their commitment to religious values and Seventh-day Adventist beliefs. Canonical correlation indicated that adolescents’ involvement in service to others is significantly related to their commitment to religious values and beliefs. Results indicated that greater commitment to religious values and Seventh-day Adventist beliefs among adolescents attending Seventh-day Adventist schools is correlated with greater involvement in service to others.     

Involvement of the insular cortex in retention of conditioned taste aversion is not time dependent

In fear-associated learning paradigms, hippocampal lesions induce memory deficits of recent but not remote memories, while amygdala lesions produce retention deficits irrespective of the age of the memory. In conditioned taste aversion (CTA), non-hippocampal mediated learning paradigm, the insular vortex (IC) has shown to have a crucial role in consolidation and storage of CTA memory. Due to the functional and anatomical similarities to the hippocampus, a time dependent role of the IC in CTA retention cannot be ruled out. To test whether the IC shows a time dependent role in CTA memory retention, male Wistar rats were CTA trained on saccharin 0.1% (LiCl 0.15M, 2% b/w, 40 min after drinking) and lesioned with ibotenic acid (200-300 nL, 5mg/mL) unilaterally into the IC 1 week or bilaterally 1 or 6 weeks after CTA. CTA memory was completely disrupted in both bilateral lesion groups but unaffected in the unilateral lesioned group. The resulting preference was comparable to that of the bilaterally IC lesioned animals exposed to the taste for the first time, proving that in these animals a complete amnesic state was achieved. Bilaterally IC lesioned rats showed normal discrimination between preferred (sucrose 5%) and non-preferred (quinone) tastes. Our data indicates that the involvement of the IC in CTA is not time dependent and that CTA memories are stored in each hemisphere separately.     

Conflicting processes in the extinction of conditioned taste aversion: behavioral and molecular aspects of latency,apparent stagnation,and spontaneous recovery

The study of experimental extinction and of the spontaneous recovery of the extinguished memory could cast light on neurobiological mechanisms by which internal representations compete to control behavior. In this work, we use a combination of behavioral and molecular methods to dissect subprocesses of experimental extinction of conditioned taste aversion (CTA). Extinction of CTA becomes apparent only 90 min after the extinction trial. This latency is insensitive to muscarinic and β-adrenergic modulation and to protein synthesis inhibition in the insular cortex (IC). Immediately afterwards, however, the extinguishing trace becomes sensitive to β-adrenergic blockade and protein synthesis inhibition. The subsequent kinetics and magnitude of extinction depend on whether a spaced or massed extinction protocol is used. A massed protocol is highly effective in the short run, but results in apparent stagnation of extinction in the long-run, which conceals fast spontaneous recovery of the preextinguished trace. This recovery can be truncated by a β-adrenergic agonist or a cAMP analog in the insular cortex, suggesting that spontaneous overtaking of the behavioral control by the original association is regulated at least in part by β-adrenergic input, probably operating via the cAMP cascade, long after the offset of the conditioned stimulus. Hence, the performance of the subject in experimental extinction is the sum total of multiple, sometimes conflicting, time-dependent processes.     

Detecting Differential Item Functioning Using Multiple-Group Cognitive Diagnosis Models

This study proposes a multiple-group cognitive diagnosis model to account for the fact that students in different groups may use distinct attributes or use the same attributes but in different manners (e.g., conjunctive, disjunctive, and compensatory) to solve problems. Based on the proposed model, this study systematically investigates the performance of the likelihood ratio (LR) test and Wald test in detecting differential item functioning (DIF). A forward anchor item search procedure was also proposed to identify a set of anchor items with invariant item parameters across groups. Results showed that the LR and Wald tests with the forward anchor item search algorithm produced better calibrated Type I error rates than the ordinary LR and Wald tests, especially when items were of low quality. A set of real data were also analyzed to illustrate the use of these DIF detection procedures.     

A General Method of Empirical Q-matrix Validation

In contrast to unidimensional item response models that postulate a single underlying proficiency, cognitive diagnosis models (CDMs) posit multiple, discrete skills or attributes, thus allowing CDMs to provide a finer-grained assessment of examinees’ test performance. A common component of CDMs for specifying the attributes required for each item is the Q-matrix. Although construction of Q-matrix is typically performed by domain experts, it nonetheless, to a large extent, remains a subjective process, and misspecifications in the Q-matrix, if left unchecked, can have important practical implications. To address this concern, this paper proposes a discrimination index that can be used with a wide class of CDM subsumed by the generalized deterministic input, noisy “and” gate model to empirically validate the Q-matrix specifications by identifying and replacing misspecified entries in the Q-matrix. The rationale for using the index as the basis for a proposed validation method is provided in the form of mathematical proofs to several relevant lemmas and a theorem. The feasibility of the proposed method was examined using simulated data generated under various conditions. The proposed method is illustrated using fraction subtraction data.