Development of a Unified Protocol for the Treatment of Emotional Disorders in Youth

This study evaluated the efficacy of the Mind Reading interactive computer software to remediate emotion recognition deficits in children with autism spectrum disorders (ASD). Six unmedicated children with ASD and 11 unmedicated non-clinical control subjects participated in the study. The clinical sample used the software for five sessions. The control sample was evaluated only on pre- and post-test performance to assess practice effects. Results showed that participants with ASD scored significantly higher on the posttest than on the pretest. As level of emotion difficulty increased, mean scores on the pretest decreased, indicating that difficulty level had a valid effect. The Mind Reading computer software appears to significantly improve the emotion recognition abilities in children with ASD.     

Providing information about diagnostic features at retrieval reduces false recognition

In the following study, participants encoded blocked DRM word lists and we varied whether they received information before test about the utility of mnemonic features that potentially discriminate between veridical and false memories. The results of three experiments revealed that this manipulation successfully reduced false recognition of critical theme words. We also found that this manipulation was effective for younger but not older adults. Furthermore, calling attention to the features in test instructions alone was sufficient for reducing false recognition and its effectiveness was not enhanced by also asking participants to rate their phenomenal experience. We argue that providing diagnostic information before test allows participants to establish more accurate expectations about the task and thus improves the efficacy of retrieval and monitoring processes that are subsequently engaged.     

Dual n-back training increases the capacity of the focus of attention

Working memory (WM) training has been reported to benefit abilities as diverse as fluid intelligence (Jaeggi et al., Proceedings of the National Academy of Sciences of the United States of America, 105:6829–6833, 2008) and reading comprehension (Chein & Morrison, Psychonomic Bulletin & Review, 17:193–199, 2010), but transfer is not always observed (for reviews, see Morrison & Chein, Psychonomics Bulletin & Review, 18:46–60, 2011; Shipstead et al., Psychological Bulletin, 138:628–654, 2012). In contrast, recent WM training studies have consistently reported improvement on the trained tasks. The basis for these training benefits has received little attention, however, and it is not known which WM components and/or processes are being improved. Therefore, the goal of the present study was to investigate five possible mechanisms underlying the effects of adaptive dual n-back training on working memory (i.e., improvements in executive attention, updating, and focus switching, as well as increases in the capacity of the focus of attention and short-term memory). In addition to a no-contact control group, the present study also included an active control group whose members received nonadaptive training on the same task. All three groups showed significant improvements on the n-back task from pretest to posttest, but adaptive training produced larger improvements than did nonadaptive training, which in turn produced larger improvements than simply retesting. Adaptive, but not nonadaptive, training also resulted in improvements on an untrained running span task that measured the capacity of the focus of attention. No other differential improvements were observed, suggesting that increases in the capacity of the focus of attention underlie the benefits of adaptive dual n-back training.     

Interpretive Artists: A Qualitative Exploration of the Creative Process of Actors

Actors, dancers, and musicians generally are referred to as artists, but many do not originate the work they perform; rather, they interpret the work of originating artists. Past models of the creative process were based on originating artists. The purpose of this study was to explore the creative process of interpretive artists, specifically actors. To further characterize the creative process of actors, this study additionally investigated (a) the social influences that undermined or enhanced an actor's creativity, (b) the tension that occurs between an actor's personal and character identities, and (c) the need for spontaneity in the creative process of actors. Semistructured interviews were conducted with 3 actors. Content analysis revealed three stages of the creative process for actors: a general preparation period, rehearsal, and performance. This model was compared with a previous model of the creative process based on originating artists. Social influences seen as enhancing creativity were clear direction, trust, freedom, respect, challenge, collaboration, and unity with the audience. Undermining social influences included reward, poor direction, evaluation, distrust, peers who stopped listening, and feeling interchangeable. The tension between an actor's personal and character identities was characterized by catharsis and difficulty in delineating boundaries. The need for spontaneity was seen as crucial in the actor's creative process. It is suggested that the actor's creative process is more improvisational, characterized by process and product co-occurring, real-time social influences, tension between personal and performing identities, and the need for spontaneity.     

Early Stages of a Psychoanalytic Treatment: The Case of Laura

This case analysis describes a young woman's jouney to integrate the experiences of having an unresponsive and nonnurturant mother and an invasive, seductive, and chronically anxious father, who functioned as the loving and responsive parent. From the outset of the analysis, mother's difficulties in attachment and empathy with her daughter's needs or fears, and father's overstimulating and intrusive relationship to his daughter, were present in the patient's dreams and in the transference. The early stage of treatment reported here describes the patient's efforts to find a self-regulatory balance between states of extreme overstimulation and excitement and of withdrawal and a fear of invasion.     

Return of Genetic Results in the Familial Dilated Cardiomyopathy Research Project

The goal of the Familial Dilated Cardiomyopathy (FDC) Research Project, initiated in 1993, has been to identify and characterize FDC genetic cause. All participating individuals have been consented for the return of genetic results, an important but challenging undertaking. Since the inception of the Project we have enrolled 606 probands, and 269 of these had 1670 family members also enrolled. Each subject was evaluated for idiopathic dilated cardiomyopathy (IDC) and pedigrees were categorized as familial or sporadic. The coding regions of 14 genes were resequenced in 311 to 324 probands in five studies. Ninety-two probands were found to carry nonsynonymous rare variants absent in controls, and with Clinical Laboratory Improvement Amendment of 1988 (CLIA) compliant protocols, relevant genetic results were returned to these probands and their consented relatives by study genetic counselors and physicians in 353 letters. In 10 of the 51 families that received results >1 year ago, at least 23 individuals underwent CLIA confirmation testing for their family’s rare variant. Return of genetic results has been successfully undertaken in the FDC Research Project. This report describes the methods utilized in the process of returning research results. We use this information as a springboard for providing guidance to other genetic research groups and proposing future directions in this arena.     

Witness Vetting: What Determines Detectives' Perceptions of Witness Credibility?

During the course of a criminal investigation witness vetting, a detective's process of determining the credibility and weight of witness information, can lead to errors in an investigation that can go virtually unchallenged. Witness confidence, opportunity to view, and type of information proffered were examined in relation to detective inferences about witness reliability, accuracy, and probable cause to arrest. Experiment 1 involved 39 sworn law enforcement officers, and experiment 2 involved 43 sworn law enforcement officers and 86 mock detectives. Participants viewed a digital recording depicting a witness describing a gas station robbery (Experiment 1) or a campus mugging (Experiment 2). Witness confidence and detectives' inferences about culprit information influenced the vetting process and lent credibility to a confident witness whose accuracy was objectively unknown. Furthermore, the evidence indicates that sworn law enforcement are comparable with untrained observers in their use of social inference cues (i.e. confidence) in determining witness credibility; however, social inference can be assuaged by the rational, rule‐governed, decision framework established for witness vetting. Social inference processes inherent in the detective‐witness dyad is influenced by legal procedures in vetting witness information. Copyright © 2013 John Wiley & Sons, Ltd.     

Event‐related potential differences in children supplemented with long‐chain polyunsaturated fatty acids during infancy

Long‐chain polyunsaturated fatty acids (LCPUFA) have been shown to be necessary for early retinal and brain development, but long‐term cognitive benefits of LCPUFA in infancy have not been definitively established. The present study sought to determine whether LCPUFA supplementation during the first year of life would result in group differences in behavior and event‐related potentials (ERPs) while performing a task requiring response inhibition (Go/No‐Go) at 5.5 years of age. As newborns, 69 children were randomly assigned to infant formulas containing either no LCPUFA (control) or formula with 0.64% of total fatty acids as arachidonic acid (ARA; 20:4n6) and various concentrations of docosahexaenoic acid (DHA; 22:6n3) (0.32%, 0.64% or 0.96%) for the first 12 months of life. At 5.5 years of age, a task designed to test the ability to inhibit a prepotent response (Go/No‐Go) was administered, yielding both event‐related potentials (ERPs) and behavioral data. Behavioral measures did not differ between groups, although reaction times of supplemented children were marginally faster. Unsupplemented children had lower P2 amplitude than supplemented children to both Go and No‐Go conditions. N2 amplitude was significantly higher on No‐Go trials than Go trials, but only for supplemented children, resulting in a significant Group × Condition interaction. Topographical analysis of the ERPs revealed that the LCPUFA‐supplemented group developed a novel period of synchronous activation (microstate) involving wider anterior brain activation around 200 ms; this microstate was not present in controls. These findings suggest that LCPUFA supplementation during the first 12 months of life exerts a developmental programming effect that is manifest in brain electrophysiology. A video abstract of this article can be viewed at: https://www.youtube.com/watch?v=oM2leg4sevs .     

The Confluence of Psychiatric Symptoms and Neurodegenerative Disease: Impact on Genetic Counseling

Hereditary neurodegenerative diseases can present with a psychiatric prodrome that overlaps with psychiatric symptoms that are not primary to these diseases. When individuals present for predictive testing while experiencing such symptoms, clinicians including genetic counselors, must proceed with caution and evaluate each situation on a case-by-case basis. Legitimate reasons may exist for moving forward with testing. Additionally predicting the consequences of testing is unrealistic so that the clinicians must do their best to prepare patients for both positive and negative results. A multidisciplinary team following the Huntington disease protocol remains the gold standard care for predictive testing for such patients. We discuss 3 case histories that demonstrate the complex nature of genetic counseling and testing in the presence of psychiatric symptoms, whether emanating from the disease itself or the results of living in an affected family.