加压素对记忆巩固过程作用的研究 Ⅰ.精氨酸加压素(AVP)对大鼠记忆巩固过程的易化作用及脑内游离氨基酸含量的变化

本文研究了精氨酸加压素易化记忆巩固过程的作用,测定了这一作用过程中脑内15种游离氨基酸含量的变化。 1.第三天建立实验前1小时皮下注射AVP(2μg/只)显著地延缓了大鼠主动逃避条件反应的消退过程。 2.给予AVP的动物在建立期皮层视区和海马两脑区的GABA(γ-氨基丁酸)含量及海马的异亮氨酸含量下降。在保持期两脑区的苏氨酸含量下降,赖氨酸含量上升,海马的谷氨酸含量下降,但两脑区的GABA含量都没有显著变化。 3.电击应激反应的实验结果表明,给予AVP的动物海马的GABA含量及皮层视区苯丙氨酸含量下降。单独注射AVP后1小时,两脑区的天冬氨酸含量下降。AVP注射后48小时,脑内各种氨基酸含量都没有明显变化。     

An ethnomethodological clarification of Husserl's concepts of “regressive inquiry” and “Galilean physics” by means of discovering praxioms

This paper offers an ethnomethodological clarification of Husserl's concepts of Galilean physics and regressive inquiry. It employs the reader's textual-practical operationalization of these concepts. With the use of a simple optical prism as a perspicuous case of a scientific instrument, the reader will be asked and instructed to make a self-reflexive inquiry into the practical contingencies of the prismatic field of reflection. The reader will discover that the geometric structures of the reflective field of the prism is an achievement and formalization of the reader's own operatlonalizations. I named these discoverable discovering operationspraxioms or practical axioms — the pre-scientific contingencies of the geometric structures of prismatic reflection.I would like to thank Mike Lynch, Eric Livingston, George Psathas and Shelley Schweizer-Bjelic for their comments.     

A Short Measure of the Revised Reinforcement Sensitivity Theory – RSQ17

The need for a research and practical tool, such as a short, reliable, and valid personality assessment test, suggests researchers to create shortened versions of original instruments. Reinforcement sensitivity questionnaire (RSQ) was created in line with some basic premises of revised Reinforcement sensitivity theory, which proposes three motivational and emotional systems: Behavioral inhibition system (BIS), responsible for scanning environment for potential threats, Behavioral activation system (BAS), responsible for aproaching behavior, and the Fight/Flight/Freeze system (FFFS), responsible for behavior in the present threat. RSQ comprises five scales: BIS, BAS, Fight, Flight, and Freeze. The aim of this study was to develop a short version of RSQ, which would be beneficial to both research and practical purposes. Item response theory analyses were used for item selection. The study comprised two samples of participants, whereby Sample 1 (N = 837, 34.6% male, aged 18 – 82, M = 31.63, SD = 13.54) served as the derivation sample, while Sample 2 (818 participants, 43.6% male, 18?75 years, M = 29.65, SD = 12.52) served as validation sample. Factorial validity of the short RSQ was examined on both Sample 1 and Sample 2. Convergent and divergent validity of the short RSQ was examined using RST-PQ, Jackson-5, BIS/BAS scales, and Big Five Inventory. The results point to satisfactory internal consistency, factorial validity, and construct validity of the short RSQ, suggesting that it is an adequate measure for research settings or other contexts which require the use of short personality questionnaires.     

生物医学人体受试者研究未来面临的挑战

人体受试者研究的伦理问题在今后将会愈益引起关注,如何看待知情同意的代理权？如何处理不同文化背景下的知情同意原则？在商业利益诱惑下背离本人健康利益和知情同意是否有效？受试者的利益回报,以及体试验研究要求的双盲,随机、对照等原则可能面临的新问是,都是人体受试者研究未来面临的挑战。     

FOK:是线索熟悉,还是目标提取?

以围棋定式为实验材料,检验了关于FOK判断的线索熟悉假说和目标提取假说。结果表明：在有线索可以利用的情况下,被试会依据线索的熟悉作出FOK判断;而在线索难以利用的情况下,被试就会依据目标的提取来作出FOK判断。该文还对FOK的研究方法提出了一点看法。     

情绪和认知方式对个体建议采纳的影响*

通过电影诱发被试的情绪,利用两个实验探讨了情绪和认知方式对个体建议采纳的影响。实验一采用选择任务,实验二采用估计任务,研究发现:(1)愉快情绪状态下的被试建议采纳程度高于愤怒的被试,场依存型被试建议采纳程度高于场独立型被试,女性比起男性更易采纳他人建议;(2)在估计任务中,无论场依存者还是场独立者,在愤怒状态下建议采纳程度无显著差异,且均低于愉快状态下。     

The Role of Family Functioning in Bipolar Disorder in Families

Investigated the association between family functioning and conflict and their links with mood disorder in parents and with children's risk for bipolar disorder. Participants were 272 families with a child between the ages of 5-17 years. Parents' history of psychiatric diagnoses and children's current diagnoses were obtained via semi-structured interviews. Parent report on the Family Assessment Device and the Conflict Behavior Questionnaire measured family functioning and conflict, respectively. Results revealed a small but significant indirect pathway from parental diagnosis of mood disorder to child bipolar disorder through impaired family functioning, via increased family conflict. Parental mood disorders were also significantly related to other negative outcomes in children, including unipolar depression and oppositional defiant disorder. Associations between parent diagnoses and family functioning changed depending on youth age, but not youth sex.     

《太平经》“周穷救急”的社会救济思想

东汉后期的道教经典<太平经>从民本思想出发,批判了社会上贫富不均、以强凌弱、以智诈愚等现象,怀着对民众的关爱和对弱者的同情,提出了"周穷救急"的社会救济思想,要求社会上层的统治者和富人们慈善布施,广散余财,以保障社会下层的贫民百姓能获得基本的生活资料,过上安稳的生活,从而构建一个和谐的社会.     

儒家的修身思想及其方法述论

修身思想是儒家学说中的一个重要组成部分.历代儒家学者都特别注重道德教化,把修身作为实现人生价值和达到人格完善的重要手段和途径.在儒家的思想学说中,既有关于崇高完美的理想人格追求,又有一套通过修身而实现人格完善的理论和方法.尽管由于时代和历史的局限,其中不免存在着一些错误和缺陷,但其对于人的自身修养的强调,以及所提倡的修身方法,是有其合理因素的,对此我们应当遵循"去其糟粕、取其精华"的原则,批判地加以继承,这不论对人的自我完善,还是对社会道德建设都是十分必要的.