The protection of patients’ rights in clinical trials

The Helsinki Declaration is a very important document regarding the protection of patients’ rights in clinical trials and one of the fundamental sources of operational principles for every ethics committee. Although they have been updated, the international guidelines for ethics committees continually fail to address certain issues pertaining to the protection of patients’ rights in clinical trials. These issues include, most significantly, the method of electing ethics committees (a free, secret ballot should be preferred to direct appointment), the avoidance of conflict of interest during the election of ethics committee members, and the necessary insurance coverage for the participants of clinical trials. Polish law should, on the other hand, be developed in such way as to not limit the effectiveness of ethics committees in protecting patients’ rights in clinical trials. The ideal solution would be to draft a uniform law concerning not only clinical trials, but all medical experiments. The opinions of experts who have been reviewing medical research projects for several years may prove to be especially valuable in this setting. This paper was presented at the 6th International Bioethics Conference on the subject of ‘The Responsible Conduct of Basic and Clinical Research’, held in Warsaw, Poland, 3–4 June 2005. The author is Chairman, Bioethics Committee of the Warsaw Regional Chamber of Physicians and Dentists.     

Connectivity among semantic associates: an fMRI study of semantic priming

Semantic priming refers to a reduction in the reaction time to identify or make a judgment about a stimulus that has been immediately preceded by a semantically related word or picture and is thought to result from a partial overlap in the semantic associates of the two words. A semantic priming lexical decision task using spoken words was presented in event-related fMRI and behavioral paradigms. Word pairs varied in terms of semantic relatedness and the connectivity between associates. Thirteen right-handed subjects underwent fMRI imaging and 10 additional subjects were tested in a behavioral version of the semantic priming task. It was hypothesized priming would be greatest, reaction time fastest, and cortical activation reduced the most for related word pairs of high connectivity, followed by related word pairs of low connectivity, and then by unrelated word pairs. Behavioral and fMRI results confirmed these predictions. fMRI activity located primarily in bilateral posterior superior and middle temporal regions showed modulation by connectivity and relatedness. The results suggest that these regions are involved in semantic processing.     

Traumatic stress, dissociation, and limbic irritability in patients with unipolar depression being treated with SSRIs

Recent evidence suggests that stressful experiences may be related to deficits in inhibitory functions and temporo-limbic epileptic-like activity. The latter may produce psychosensory seizure-like symptoms that may also appear in nonepileptic conditions. This study assesses whether the increased presence of the seizure-like symptoms in 113 unipolar depressive patients treated with SSRIs is associated with significantly more severe symptoms of depression, traumatic stress, and dissociation in comparison with 86 healthy controls. Results indicate that seizure-like symptoms in depressive patients have significant association with depression, symptoms of dissociation, and traumatic stress. This association suggests that processess generating seizure-like symptoms may be related to symptoms of depression, traumatic stress, and dissociation.     

《大学生主观幸福感量表》的编制

根据国内外关于主观幸福感的文献和已有的研究经验,编制了大学生主观幸福感问卷。以往大多数研究认为,主观幸福感由生活满意度和情绪体验两个基本成分构成,本研究认为主观幸福感还应包括社会性行为和人际关系等成分。对376名大学生进行初测,通过探索性因素分析,表明大学生主观幸福感由自我满意、家庭满意、消极情绪、积极情绪、精力、生活满意、社会性行为和人际关系8个维度构成,共41个项目。对511名大学生施测41个项目的主观幸福感问卷,进行验证性因素分析,结果表明,上述结构是合理的。     

National Survey of Client's Perceptions of Chinese Psychotherapist Practices

The present study is a cross-sectional survey that investigates ethical practices among Chinese psychotherapists from the perspective of a large representative sample of Chinese clients (N?=?1,100). In reports from clients, we found that psychotherapists did poorly in providing informed consent and had other ethical difficulties in the therapeutic setting and with dual relationships. We conclude that Chinese culture, especially Confucianism, had significant impact on the attitudes toward the psychotherapists' ethical practices, which complicated ethical dilemmas. It is important for cross-cultural psychotherapists to become sensitive to the influences of traditional Chinese culture when counseling Chinese clients.     

Do Christian Denominations Exhibit Higher Rates of Alcohol Consumption? A Study of Korean American Women in California

Although Korean American women show high levels of involvement in religious practices and high prevalence of alcohol consumption, no studies have assessed the association between religious denomination and alcohol intake among this group of women. This cross-sectional study examined the associations of religious denomination and religious commitment to alcohol consumption among Korean American women in California. Polychotomous regression models were used to provide estimates of the associations between religious denomination and religious commitment to alcohol consumption. Catholic Korean American women (OR 5.61 P < 0.01) and Independent Christian women (OR 4.87 P < 0.01) showed stronger associations to heavy alcohol consumption when compared to Conservative Christian Korean American women. Path analysis suggested that specific denominations had both direct and indirect effects on the outcome of interest, and that religious commitment and drinking models served as moderators for this phenomenon.     

A Cross-Country Evaluation of Cheating in Academia—A Comparison of Data from the US and the Czech Republic

In this study, we examine differences in cheating behaviors in higher education between two countries, namely the United States and the Czech Republic, which differ in many social, cultural and political aspects. We compare a recent (2011) Czech Republic survey of 291 students to that of 268 students in the US (Klein et al., 2007). For all items surveyed, CR students showed a higher propensity to engage in cheating. Additionally, we found more forms of serious cheating present in the Czech sample. In all cases, the differences between the US and Czech samples were statistically significant.     

Religiosity in Christian Educational Leadership

This study investigated the primary leadership orientations of Christian school leaders and their association with religiosity. To this end, this study adopted two lines of thought and research; the religiosity theory proposed by Batson, Schoenrade, and Ventis (1993) and the leadership theory proposed by Bolman and Deal (1997). Participants of this study were 206 K-12 school leaders affiliated with a Protestant church in the United States. According to the analysis, the human resource frame was the primary leadership frame of the school leaders, and the structural frame was a close second. Quest religiosity was inversely related to the four frames of structural, human resource, political, and symbolic leadership, whereas intrinsic and extrinsic religious orientations were positively related to the frames. Despite this pattern of relationship, in general, the analysis found little statistically meaningful relationship between religiosity and leadership, and this fact engenders an important question whether or not religion has any impact on Christian education, leadership, and behavior.     

Prevalence and Predictors of Posttraumatic Growth in Accidentally Injured Patients

This study examined prevalence and predictors of posttraumatic growth in 180 accidentally injured patients of mainland China in their convalescence stage, investigating its relationships with demographic and accidental injury variables, personality, posttraumatic stress disorder (PTSD) symptoms, and coping styles. Our results showed that posttraumatic growth (PTG) presented mostly in the domain of Relating to Others and indicated that PTG was significantly related to marital status, educational level, personality, coping styles, and PTSD symptoms. Avoidance of PTSD symptoms, Openness to experience, and positive coping were significant predictors of PTG. The findings emphasize that when promoting PTG of accidentally injured patients, healthcare providers should facilitate patients utilizing personal resources, understand PTG coexists with PTSD symptoms, and adjust interventions based on the coping styles the patients have adopted.     

The importance of social and ideal social dimensions in self‐congruity research

Chronic or situational self‐construal moderates the effects of four self‐congruity (SC) dimensions (i.e., actual, ideal, social, and ideal social) on brand evaluations. Past research has mainly focused on the actual and ideal SC effects; these effects have been found to be stronger than the social and ideal social SC effects. However, the findings of past research are based on samples from individualistic cultures. Individualists have a dominant independent self‐construal. We conduct two experiments to show that the social and ideal social SC effects are stronger than the actual and ideal SC effects for individuals with a dominant interdependent self‐construal. In Study 1, using samples from collectivistic cultures, four SC effects are compared. In Study 2, we examine how primed self‐construal, whether independent or interdependent, impacts the four SC effects. This research documents the importance of the social and ideal social dimensions in SC research.