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ISOLATING BEHAVIORAL MECHANISMS OF INTERTEMPORAL CHOICE: NICOTINE EFFECT ON DELAY DISCOUNTING AND AMOUNT SENSITIVITY 下载免费PDF全文
Many drugs of abuse produce changes in impulsive choice, that is, choice for a smaller—sooner reinforcer over a larger—later reinforcer. Because the alternatives differ in both delay and amount, it is not clear whether these drug effects are due to the differences in reinforcer delay or amount. To isolate the effects of delay, we used a titrating delay procedure. In phase 1, 9 rats made discrete choices between variable delays (1 or 19 s, equal probability of each) and a delay to a single food pellet. The computer titrated the delay to a single food pellet until the rats were indifferent between the two options. This indifference delay was used as the starting value for the titrating delay for all future sessions. We next evaluated the acute effects of nicotine (subcutaneous 1.0, 0.3, 0.1, and 0.03 mg/kg) on choice. If nicotine increases delay discounting, it should have increased preference for the variable delay. Instead, nicotine had very little effect on choice. In a second phase, the titrated delay alternative produced three food pellets instead of one, which was again produced by the variable delay (1 s or 19 s) alternative. Under this procedure, nicotine increased preference for the one pellet alternative. Nicotine‐induced changes in impulsive choice are therefore likely due to differences in reinforcer amount rather than differences in reinforcer delay. In addition, it may be necessary to include an amount sensitivity parameter in any mathematical model of choice when the alternatives differ in reinforcer amount. 相似文献
223.
Paul E. Priester Josh Scherer Jesse A. Steinfeldt Asma Jana-Masri Terri Jashinsky Janice E. Jones Cher Vang 《Pastoral Psychology》2009,58(3):315-322
This study examines the prevalence of endorsing the twelve step approach and the use of prayer, meditation, and holistic techniques
in a national sample of 139 substance abuse treatment centers. Ninety one percent of the programs endorsed a twelve step orientation.
Twenty six percent of the programs actively used prayer and 58% used meditation as a component of treatment. Thirty three
percent of the programs used some form of a self-designated holistic technique. There was a divergent range of techniques
that were used by programs, falling into four broad categories: (1) nutrition, exercise, relaxation and physical health; (2)
recreation and adventure-based activities; (3) religious and spiritual practices; and (4) the use of specific therapy modalities. 相似文献
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Rosenthal R 《Psychological science》1994,5(3):127-134
The relationship between scientific quality and ethical quality is considered for three aspects of the research process: conduct of the research, data analysis, and reporting of results. In the area of conducting research, issues discussed involve design, recruitment, causism, scientific quality, and costs and utilities. The discussion of data analysis considers data dropping, data exploitation, and meta-analysis. Issues regarding reporting of results include misrepresentation of findings, misrepresentation of credit, and failure to report results as a result of self censoring or external censoring. 相似文献
226.
Katherine A. Schneider Jill E. Stopfer June A. Peters Ellen Knell Gladys Rosenthal 《Journal of genetic counseling》1997,6(2):147-167
Complexities abound in the identification and management of families at increased risk for inherited forms of cancer. One of the ways to learn as a profession how best to provide cancer risk counseling (CRC) is to share counseling experiences. Such cases can provide insight into the issues raised by families and ways in which genetic counselors have handled complex situations. Here we describe three CRC cases initially presented at the 1995 American College of Medical Genetics meeting. The first case involves balancing the importance of informing a family of the presence of an inherited cancer syndrome with the family's right not to know. The second case illustrates the difficulties in assisting an individual to make medical management decisions in the face of uncertain risk information. The third case describes the complex interactions with a woman before and after her decision to have prophylactic surgery.
(affiliated with Long Beach Memorial Breast Center at the time of counseling) 相似文献
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In this paper, we will present a case history of a disabled network which includes a multiproblem family and the social service agencies serving it. We will describe a five-step model for effective intervention into the entire system. Social service agents frequently become overwhelmed and therefore impotent in their attempts to help multiproblem families. In such cases, agents reflect the family's dysfunction by becoming dysfunctional themselves and their actions serve to increase the family's alienation from its community by reinforcing its stigmatized self-image. Our model focuses on building boundaries and creating hierarchies which encourage individuation within the family and empowers the network to effectively meet family needs. 相似文献
230.
Three modeling therapy formats (overt modeling with a standard hierarchy of situations. covert modeling with the standard hierarchy, and covert modeling with a self-tailored hierarchy) were compared to assess their relative efficacy in developing assertive skills. Half the subjects in each treatment condition received or did not receive generalization training. Significant within-group improvement was indicated on four self-report measures. Overall, the results suggest that covert modeling was as effective as overt modeling or covert modeling plus self-tailoring for instating assertion among nonassertive college women. 相似文献