Auditory specific fear conditioning results in increased levels of synaptophysin in the basolateral amygdala

Auditory fear conditioning is one of the most well characterized models used in studies of learning and memory. In order to ensure the animals have been conditioned to fear the auditory stimulus, animals are generally tested for their response to this stimulus in a different context to that used for training. For this reason it is often unclear how much contextual fear conditioning the animals also acquire when they are trained. In this study, we have established a protocol for fear conditioning in mice which is explicit for auditory cues; mice trained using this protocol, show a very low fear response to contextual cues encountered during training. We have undertaken analysis to look for potential brain changes associated with this model by measuring levels of the synaptic vesicle protein, synaptophysin, in the basolateral nuclei of the amygdala following auditory fear conditioning. Our results show levels of synaptophysin were significantly higher in mice which learnt to associate the auditory stimulus with fear, in comparison to all non-learning control animals. These findings support the idea that synaptic plasticity associated with formation of fear conditioning to a single specific conditioned stimulus occurs within the basolateral nuclei of the amygdala. Furthermore, our results demonstrate the usefulness of this model in looking for changes in the brain specific for a defined learning event.     

Daily Hassles and African American Adolescent Females�� Psychological Functioning: Direct and Interactive Associations with Gender Role Orientation

Given that stressors may accumulate across the life span, the extent to which daily hassles are associated with African American females?? psychological functioning during the adolescent years remains an important question. Understanding the potential impact of daily hassles is important due to indications that African American women report greater daily hassles and have higher incidence rates of stress-related disorders. The current study examines the relationship between daily hassles and psychological functioning (e.g., depression and anxiety symptoms) among 103 U.S. African American adolescent females (M?=?15.50; SD?=?1.70) residing in a moderately-sized Midwestern city. Additionally, this investigation explores gender role orientation as a moderator of this relationship. Results indicated that increased daily hassles were associated with greater depressive and anxiety symptoms. Also, this investigation provides some support for the direct and moderating role of gender role orientation. A greater feminine or androgynous role orientation was associated with fewer depressive and anxiety symptoms. In addition, although not directly associated, this investigation indicated that a masculine role orientation moderated the association between daily hassles and girls?? psychological outcomes. Specifically, among African American adolescent females with a greater masculine role orientation, increased daily hassles were associated with reduced psychological functioning (e.g., greater depressive and anxiety symptoms). Neither feminine nor androgynous role orientation, however, moderated the relationship between daily hassles and psychological functioning (e.g., depressive and anxiety symptoms). Implications of findings are discussed.     

Is there a hierarchy of social inferences? The likelihood and speed of inferring intentionality, mind, and personality

People interpret behavior by making inferences about agents' intentionality, mind, and personality. Past research studied such inferences 1 at a time; in real life, people make these inferences simultaneously. The present studies therefore examined whether 4 major inferences (intentionality, desire, belief, and personality), elicited simultaneously in response to an observed behavior, might be ordered in a hierarchy of likelihood and speed. To achieve generalizability, the studies included a wide range of stimulus behaviors, presented them verbally and as dynamic videos, and assessed inferences both in a retrieval paradigm (measuring the likelihood and speed of accessing inferences immediately after they were made) and in an online processing paradigm (measuring the speed of forming inferences during behavior observation). Five studies provide evidence for a hierarchy of social inferences-from intentionality and desire to belief to personality-that is stable across verbal and visual presentations and that parallels the order found in developmental and primate research.     

Patterns of Association Among Multiple Motivations and Aspects of Achievement in Reading

The present study investigated the multivariate relationships between several aspects of motivation and achievement in reading. Canonical correlation analysis was used to examine patterns of associations for reading information texts in Phase I and for reading literary texts in Phase II. The samples were 923 and 225 seventh graders, respectively. Results revealed three multivariate patterns for information text, whereas one pattern was observed for literary text. An explanation for the difference between reading motivation for information text and literary text is provided based on distinctions between these genres. Additionally, findings showed that undermining motivations predicted students’ reading achievement more strongly than affirming motivations. The theoretical and practical implications of the study are discussed.     

The discrimination of facial expressions by typically developing infants and toddlers and those experiencing early institutional care

Early experience likely plays an important role in the development of the ability to discriminate facial expressions of emotion. We posited that compared to children reared with their biological families (n=72), abandoned children being reared in institutions (n=39) should demonstrate impairments in this ability. The visual paired comparison procedure was utilized to assess the abilities of 13- to 30-month-old children to discriminate among multiple pairs of photographs of facial expressions. Both groups exhibited a normative profile of discrimination, with no group differences evident. Such findings suggest that early institutionalization does not affect the ability of 1- to 3-year-olds to discriminate facial expressions of emotion, at least as inferred by the Visual Paired Comparison Procedure.     

Relation of emotion-related regulation to children's social competence: a longitudinal study

The differential relations of children's emotion-related regulation (i.e., effortful control and impulsivity) to their personality resiliency, adult-rated popularity, and social competence were examined in children who were 4.5-7.9 years old and who were remeasured 2 years later. Parents and teachers reported on all constructs, and children's attentional persistence was observed. Structural equation modeling was used to test the mediating role of resiliency on the relations between regulation/control and popularity using two-wave longitudinal data. The results provide some evidence of the mediating role of resiliency in the relations between effortful control and popularity, provide some evidence of bidirectional effects, and also buttress the view that emotional regulation should be differentiated into effortful and reactive forms of control.     

Maladaptive appraisals as a risk factor for posttraumatic stress: a study of trainee firefighters

This study tested the proposal that catastrophic appraisals are a risk factor for developing stress reactions after trauma. Trainee firefighters (N = 82) were assessed during training (and before trauma exposure), and 68 firefighters were subsequently reassessed 6 months after commencing firefighter duty (after trauma exposure). Initial assessment included the Clinician Administered PTSD Scale, the Traumatic Events Questionnaire, and the Posttraumatic Cognitions Inventory. The Clinician Administered PTSD Scale was again administered approximately 20 months after initial assessment and after trauma exposure. Posttraumatic stress at follow-up was predicted by pre*trauma catastrophic thinking (24% of variance). These findings accord with cognitive models predicting that a tendency to catastrophize about negative events is a risk factor for developing posttraumatic stress symptoms.     

A statewide survey of audiologists regarding auditory processing disorders

This study surveyed all licensed Arkansas audiologists (N = 127) regarding auditory processing disorders in children and adults, with 16 items covering demographic information, knowledge, identification and diagnosis, service provision, and referral. Analysis indicated 40% and 35% of the 62 respondents were "very" or "somewhat comfortable" with diagnosing auditory processing disorders in adults and children, respectively. In the current work setting, 58% did not provide auditory processing testing, 44% had never performed such testing, and 40% did not answer a question related to referral sources. The lack of consistent testing or referral probably leaves community persons with auditory processing disorders at risk for being overlooked or misdiagnosed.     

Categorical versus dimensional status of borderline personality disorder

One of the many controversies concerning the borderline personality disorder (BPD) diagnosis is whether the construct refers to a categorical or dimensional variable. The current study used Meehl's (1973) maximum covariance analysis to investigate this issue. The charts of 409 psychiatric inpatients were systematically reviewed for the presence of BPD and dysthymic symptoms. Charts of 244 inpatients were also reviewed to assess the presence of indicators of male sex, a categorical variable. The results for BPD and dysthymia were consistent with a dimensional model, whereas those for male sex were consistent with a categorical model. A dimensional model of classification of BPD is recommended, and suggestions for future research are provided.     

Infantile spasms: facial expression of affect before and after epilepsy surgery

This is a longitudinal study of facial expression of affect in 28 children with intractable infantile spasms who underwent epilepsy surgery. After a mean follow-up period of 1.8 years, there was a significant increase in positive affect, a significant decrease in neutral affect, and no change in negative affect during a nonverbal communication paradigm. These findings were unrelated to surgical (i. e., side of surgery, type of surgery) or seizure-related variables (i.e., seizure control, age at onset of illness, duration of illness, change in antiepileptic drugs). Comparison of affect in a subgroup of 16 patients with those of 32 normal subjects suggest a normal age-related increase in the use of positive affect. Both before and after surgery, the patients used the most positive affect while not communicating. They also used significantly more positive affect during while requesting objects or assistance rather than during social referencing. Intractable infantile spasms might be associated with reduction in the facial expression of positive affect and with impaired use during social communication.