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21.
Glucose effects on memory: behavioral and pharmacological characteristics   总被引:4,自引:0,他引:4  
Recent findings indicate that post-training glucose injections can modulate memory storage for inhibitory (passive) avoidance training. Experiment I extended these findings to determine whether glucose, like other memory modulating treatments, enhances memory storage when administered after training with low footshock and impairs memory storage after high footshock training. In Experiment I, male Sprague-Dawley rats were trained in a one-trial inhibitory avoidance task using either a brief footshock (0.5 mA, 0.7 s) or slightly more intense footshock kept on until escape (0.7 mA, mean escape latency = 3.4 s). Immediately after training, each rat received a subcutaneous injection of glucose (100 mg/kg). When tested for retention performance 24 h later, the glucose-injected animals exhibited enhanced retention performance for low footshock training and impaired retention for high footshock training. Experiment II determined whether pretreatment with adrenergic antagonists blocked the effects of glucose on memory. Pretreatment with the alpha- or beta-adrenergic receptor antagonists, phenoxybenzamine, or propranolol, respectively, had no effect on acquisition or retention in animals trained with the brief footshock and did not affect glucose facilitation of that memory. In animals trained to escape footshock, phenoxybenzamine did not attenuate the amnesia produced by glucose. Propranolol-pretreated animals had impaired retention whether or not they received post-training amnestic injections of glucose; glucose had no effect on retention in these amnestic animals. These findings add further support to the view that glucose release after training and treatment may represent a physiological response subsequent to epinephrine release in modulating memory storage processing.  相似文献   
22.
D Klein  P Belcastro  R Gold 《Adolescence》1984,19(76):805-815
Several inherent limitations to secondary school sex education program evaluations are: limited generalizability, lack of longitudinal research, and no clear consensus of program outcomes. With a Bureau of Health Education, Center for Disease Control study as the criterion for program outcomes, a study was undertaken to examine the immediate and long-term impact of sex education upon program participants. Two of the 20 schools in the CDC study identified as having exemplary sex education programs provided access to their students and alumni. Inventories which measured perceived achievement of 33 sex education outcomes were piloted for reliability and validity. Each inventory examined participant changes in knowledge, understanding of self, values, interaction skills, self-esteem, and fear of sex-related activities. Students were surveyed in school; alumni were surveyed through the mail. Response rates ranged from 30 to 100 percent for students and alumni at both schools. Overall there was no statistically significant difference between the perceptions of students and alumni as to achievement of investigated outcomes. Alumni responses at one school did, however, indicate some potentially weak areas of their school's program with respect to values and interaction skills outcomes. It appears that program impact may decrease with time. Thus, isolating and addressing the factors involved may be necessary. This would assist program planners and instructors to strengthen curricula and program activities in order to enhance the overall impact of sex education. The present study supports the notion that positive gains are achieved as a result of each school's sex education program, and these gains remained over time.  相似文献   
23.
A representative nationwide survey of elderly in nursing home facilities was conducted by the Lutheran Council U.S.A. Visitation by family ministers and facility chaplains, a major study focus, was characterized by the elderly as not meeting their needs in terms of frequency and time available with clergy. Time constraints of the clergy are communicated to the elderly, who are understanding but nevertheless felt shortchanged. The elderly without visits from relatives or significant others are particularly vulnerable. Dominant themes within pastoral care visitation are highlighted.Dr. Uhlman is Director of Research and Evaluation and Reverend Steinke is Director of the Clinical Pastoral Education Program with Mental Health Services of the Roanoke Valley, 920 South Jefferson Street, Roanoke, Virginia 24016. The authors wish to acknowledge the Aid Association for the Lutheran Insurance Company and Concordia Teachers College (River Forest, Illinois), which assisted with financial costs and data analysis. Special recognition and appreciation should be noted for the elderly respondents whose participation made our experience both rewarding and enlightening.  相似文献   
24.
An experiment is reported in which 10 Ss possessing normal hearing were required to make discriminations of continuity or interruption in a longer less intense signal (Tone A) which alternated in time with a shorter more intense signal (Tone B). The signals were presented dichotically with Tone A at the right ear. Three Tone B frequencies of 300, 1000, and 4000 cps and five Tone A frequencies somewhat near each of the Tone B frequencies were employed. The results demonstrated that as Tone A was nearer to Tone B in frequency, continuity thresholds in Tone A occurred at longer durations of Tone B. The results are discussed in terms of a central neural model.  相似文献   
25.
Three different coding schemes, i.e., transformations between stimuli and responses, were used in a continuous information transmission situation. The stimuli were groups of binary digits and S was required to transform these into verbal equivalents of combinations formed by taking various sets of the English letters. Three codes, one based on communication theory, one based on Miller’s (1956) chunking hypothesis, and a combination of the first two were used. In addition, two levels of stimulus redundancy, zero and 0.5 were used. Time to complete the task and errors were the de-pendent variables. The Ss were run for twelve days. The basic result was that Ss transmitted information at a constant rate regardless of the code or redundancy level used.  相似文献   
26.
Judgments of the location of short bursts of noise in sentences were used to reveal perceptual segmentation of sentences. It was assumed that segmentation would correspond to major constituent boundaries. In order to control for correlated variables of pitch and intonation, identical acoustic material was provided with alternate constituent structures. It was found that differences in response to identical strings were predicted by the points of variation in constituent structure.  相似文献   
27.
Hardware is described that permits bidirectional transfer of data between the Commodore 64 and an IBM-compatible PC. Commercial terminal programs can be used to transmit data. The hardware, which can be constructed for less than $15, opens up several opportunities for making good use of the cost-effective C64 computer.  相似文献   
28.
In the decade since professional counselor regulation was widely debated, more than half of the states have legislated regulation, and it is sought in others. The extent to which counselors in a state currently pursuing legislation are familiar with potential consequences of legislated regulation was examined. Most counselors were found to be unfamiliar with potential negative consequences of regulation, and most were desirous of more information regarding these issues. Implications of the findings for the profession are presented.  相似文献   
29.
30.
We evaluated the effects of several choice-related variables on the work performance of adults with severe handicaps. After assessing client work preferences, three choice-related situations were presented: (a) providing clients with the opportunity to choose a work task, (b) assigning a preferred task, and (c) assigning a nonpreferred task. Results indicated that clients attended to work tasks almost twice as much when they chose their tasks and when assigned to work on preferred tasks versus when assigned to work on nonpreferred tasks. Results are discussed regarding the need to assess systematically the effects of choice-related variables.  相似文献   
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